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Covid-19 Vaccine – Pipeline Review, 2020: Medicagos Virus-Like Particle to Prove Beneficial for Controlling the Pandemic

April 17, 2020 | Healthcare

The coronavirus pandemic, also known as the Covid-19 pandemic, has exhibited far-reaching consequences beyond the spread of the infection and futile efforts to quarantine it. Concerns have now shifted towards unveiling an effective vaccine to control this infamous pandemic. According to the Johns Hopkins University & Medicine’s Coronavirus Resource Center, as of April 13th, there were around 120,000 deaths and more than 1.9 million cases attributed to coronavirus. Experts believe that it would take approximately 12-18 months to create a new vaccine. Hence, several companies are participating in the rat race to develop one owing to the rapid spread of the disease. This information is given in a recent report, titled, “Covid-19 Vaccine– Pipeline Review, 2020” by Fortune Business Insights™.


Sinovac to Conduct Human Clinical Trial on SARS-CoV-2 Vaccine Candidate


In April 2020, Sinovac Biotech Ltd., a biopharmaceutical company headquartered in China, bagged approval to conduct a human clinical trial on SARS-CoV-2 vaccine candidate. It is inactive. The development of this vaccine began by the end of January 2020. Scientists working in Sinovac were racing to finish the comprehensive preclinical studies by collaborating with prominent research institutions in China. Amongst those studies, an animal challenge study proves that the vaccine candidate is capable of protecting animals without the requirement of antibody-dependent enhancement. Besides, this candidate would be able to neutralize virus strains from numerous countries. It would also support the potential of this vaccine to prevent the spread of Covid-19 worldwide.


Researchers of Imperial College Develop mRNA Vaccine Candidate to Combat Against Covid-19


In March 2020, the officials of Imperial College London, a world-class university with a mission to benefit society through excellence in business, medicine, engineering, and science, announced that the researchers of the department of infectious disease are taking ground-breaking efforts in developing a mRNA vaccine to fight against Covid-19. The academic institution claims to possess the technology required to create a vaccine with top speed that has never been witnessed before. mRNA vaccines are anticipated to be cheaper and faster to manufacture backed by their synthetic nature. They also do not contain any attenuated or live virus. The candidate vaccine was developed just within 14 days of receiving the sequence from China. The officials are planning to move towards clinical trial in the upcoming summer as it was being tested on animals since February 10th


To get a detailed report summary and research scope of this market, click here:


https://www.fortunebusinessinsights.com/covid-19-vaccine-pipeline-review-2020-102651


Medicago Discovers New Virus-Like Particle (VLP) of Covid-19


In March 2020, Medicago, a leading clinical-stage biopharmaceutical company headquartered in the U.S., declared the production of a Virus-Like Particle (VLP) of Covid-19. It was developed only 20 days after procuring the SARS-CoV-2 gene. It is considered to be the first step in creating a vaccine for controlling the pandemic. The VLP will soon undergo preclinical testing for efficacy and safety. Once it is done, the experts of the company would try to begin human trials of the vaccine till summer 2020 (July/August). But this will be done only after discussing thoroughly with the concerned health agencies.


The company is also developing antibodies against SARS-CoV-2 by using its technology platform. To do so, it has joined hands with the Infectious Disease Research Centre under Laval University. The centre is headed by Dr. Gary Kobinger who had previously helped in the development of treatment options and a vaccine for Ebola. The SARS-CoV-2 antibodies may potentially be used to treat people affected by the virus. The Canadian Institutes for Health Research (CIHR) is currently funding the research in part.


Fortune Business Insights™ provides a list of all the companies who are persistently striving to conduct research and development activities for creating a new vaccine for Covid-19:



  • Sanofi

  • Johnson & Johnson

  • GlaxoSmithKline

  • Pfizer

  • Medicago

  • Altimmune

  • Takis Biotech

  • INOVIO Pharmaceuticals, Inc.


A few of the most recent industry developments:



  • April 2020: Takis Biotech, a provider of high quality services in infectious diseases, immunology, oncology based in Rome, and Applied DNA Sciences Inc., an American high-technology company teamed up to include a fifth vaccine candidate under their Covid-19 vaccine development program. All the vaccines are likely to be produced this month at Applied DNA’s facility in New York. These vaccine candidates have been already approved by Italy’s Ministry of Health. It would enable the companies in moving these candidates towards preclinical animal testing. It would occur in late April 2020.

  • March 2020: Altimmune, a biotechnology company headquartered in the U.S., announced that it has successfully completed designing a vaccine for Covid-19. The company has also finished synthesis of this intranasal and single-dose vaccine. It was developed by utilizing the company’s in-house technology and it is presently boosting the development of vaccine toward manufacturing and animal testing. As per the company officials, this new vaccine would be capable of protecting human from respiratory infections that mainly affect the lower and upper airways.


Further Report Findings-



  • More than 160 COVID-19 vaccine and treatment candidates are under research and development, as of April 13th.

  • It has become very crucial to develop a vaccine as soon as possible owing to the impact on the economy due to the lockdown, rising death toll, and rapid spread of the outbreak.

  • The first ever case was reported on January 23rd in the U.S.

  • Till date, only 4 vaccine candidates have reached the stage of human clinical trials.

COVID-19 VACCINE PIPELINE REVIEW 2020

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