Bioseparation Systems Market Size, Share, and Industry Analysis, By Product Type (Chromatography Systems, Filtration Systems, Centrifuges, Magnetic Separation Systems, and Others), By Application (Clinical, Diagnostics, and Research), By End-user (Biopharmaceutical and Biotechnological Companies, Diagnostics Centers, CROs & CDMOs, and Others), and Regional Forecast, 2025-2032

The global bioseparation systems market is witnessing significant growth due to rising research and development activities and the growing demand for biopharmaceutical products. The systems refer to the integral components utilized in the biotechnology and biopharmaceutical manufacturing. These systems focus on the isolation and purification of biological molecules and the separation of complex biological mixtures. The systems isolate and purify biological molecules such as proteins, nucleic acid, and cells from the complex mixtures. These systems are used in  various application areas, such as cell and gene therapies, vaccine production, diagnostics, and the biopharmaceutical analysis.

Further, key players are launching new products, propelling the growth of the market.

• For instance, in April 2024, Waters Corporation launched the Alliance iS Bio HPLC System. This system addressed the operational and analytical challenges of biopharma quality control (QC) laboratories and combined advanced bio-separation technology. Such launches promote the growth of the market.

Bioseparation Systems Market Driver

Significant Product Launches by Key Players to Drive Industry Growth

The market is witnessing strong demand for protein purification due to an increase in the production of vaccines, gene therapies, molecular diagnostics, genomic and proteomic research, drug discovery, and others. In such applications, bioseparation systems are used. Furthermore, the systems offer enhanced purity, safety, and precise separation of biological samples. Such a wide range of applications of the systems have shifted the focus of key players to launch advanced products for bioseparation, driving the growth of the market.

• For instance, in September 2022, Astrea Bioseparations launched the Nereus LentiHERO lentiviral vector (LVV) purification technology with AstraAdept, the company’s proprietary nanofiber material. This technology aimed to address the challenges associated with purifying the large and fragile products used in cell and gene therapy. Such product launches boost market growth.

Download Free sample to learn more about this report.

According to data published by the World Health Organization (WHO), there is a growing burden of cancer, with a 77.0% increase from over 20.0 million cases in 2022 to 35.0 million cases in 2050.

Bioseparation Systems Market Restraint

Shortage of Skilled Professionals May Hamper the Growth of the Market

Despite the increasing demand for advanced treatment and diagnostics products, the shortage of skilled professionals in laboratories hampers the expansion of the bioseparation systems market. The systems require highly specialized knowledge to operate, maintain, and optimize complex technologies. Further, the lack of adequately trained personnel limits the efficient utilization of these systems, leading to inefficiencies in operations and increased turnaround time for experiments. Such factors hamper the growth of the market.         

• For instance, in September 2023, according to an article published by Labiotech UG, around 60,000 job vacancies in the biopharmaceutical sector indicate a labor shortage of 8.0% in the industry.

Such a large number of vacancies for skilled professionals hampers the growth of the market.

Bioseparation Systems Market Opportunity

In recent years, the advancements in cell and gene therapy have bolstered the scenarios for the bioseparation systems market. The rising demand for personalized treatment options for various chronic diseases, genetic diseases, and autoimmune diseases, leads to increased research and development activities for cell and gene-based therapy. Such scenarios boost research activities and the adoption of bioseparation systems for best outcomes. Additionally, increasing collaboration activities, facility launches among key players to expand the facilities, and launches in gene and cell therapy are expected to propel the growth of the market during the forecast period.

• For instance, in October 2023, Bayer AG established its first cell therapy launch facility in Berkeley, California. This site aimed to launch groundbreaking cell therapy products and innovation in product development and manufacturing. Such scenarios promote the growth of the bioseparation systems market during 2024-2032.

Key Insights

The report covers the following key insights:

• Overview: Technological Advancements in Bioseparation Systems
• New Product Launches, By Key Players
• Key Industry Developments - Mergers, Acquisitions, Partnerships
• Impact of COVID-19 on the Market

Segmentation

Analysis by Product Type

Based on product type, the market is divided into chromatography systems, magnetic separation systems, filtration systems, centrifuges, and others.

The chromatography systems segment held a substantial share of the market. The growth of the segment is attributed to the versatility of these systems. The systems are present in different types, such as high-performance liquid chromatography (HPLC), affinity chromatography, size-exclusion chromatography, and others that are used for bioseparation processes. These systems are precise and accurate and play a crucial role in ensuring the purity and quality of biopharmaceutical products.

Additionally, an increase in strategic activities among key players in the market for advanced product offerings is expected to propel the growth of the segment.

• For instance, in March 2023, Thermo Fisher Scientific Inc. unveiled a new line of low-flow HPLC columns µPAC Neo HPLC Columns. These are used to improve separation performance and stability of biologically complex samples. Further, these columns enable the accurate discovery of disease biomarkers, identification of peptides to determination of protein quantities, and post-translational modifications. Such launches promote the growth of the segment in the market.

Analysis by Application

Based on application, the market is divided into clinical, diagnostics, and research.

The clinical segment held a significant share of the global bioseparation systems market. The segment growth is augmented by the increasing demand for personalized medicines for chronic diseases. In addition, rising research and development activities for launching gene- and cell-based therapies and vaccine production for infectious diseases are driving the segment growth.

Furthermore, an increase in fundraising initiatives for product launches in the bioseparation systems for purifying large and fragile products used in cell and gene therapy boosts the segment growth.

• For instance, in March 2023, TeraPore Technologies, a developer of advanced nanofiltration membrane systems for biomanufacturing, secured USD 10.0 million in new financing. This funding is used to launch its IsoBlock virus filter, which offers high-capacity, high-yield bioseparation solutions that enable controllable, consistent purification processes for the manufacturing of novel therapeutics and biologics. Such initiatives boost the growth of the segment.

Analysis by End-user

Based on end-user, the market is segmented into biopharmaceutical and biotechnological companies, diagnostics centers, cros & cdmos, and others.

The biopharmaceutical and biotechnological companies segment held a significant portion of the market. The segment growth is augmented by the presence of advanced facilities and skilled professionals, as well as capital for performing research activities. The companies are involved in the research of innovative drugs, vaccines, and other products that require bioseparation systems for purification of the sample. Such scenarios promote the adoption of the systems in biopharmaceutical and biotech companies.

• For instance, in August 2024, Precigen, Inc., a biopharmaceutical company involved in the development of innovative gene and cell therapies, announced the strategic reprioritization of its clinical portfolio and streamlining of resources to focus on the commercialization of the PRGN-2012 AdenoVerse gene therapy for respiratory papillomatosis. Such scenarios promote the growth of the segment in the market.

Regional Analysis

To gain extensive insights into the market, Download for Customization

Based on region, the market has been studied across Europe, North America, Asia Pacific, Latin America, and the Middle East & Africa.

North America accounted for a significant share of the global bioseparation systems market in 2023. The regional growth is attributed to the presence of key players in the market with advanced product offerings. Further, the presence of advanced facilities for research and development of new therapies and drugs leads to the growth of the region.

Europe has a substantial share of the bioseparation systems market owing to the presence of key biopharmaceutical and biotech companies, with expanded facilities for research and development. In addition, the presence of key players with strategic activities and advanced product offerings boosts the growth of the region.

• For instance, in January 2022, Eppendorf acquired Koki Holdings Co., Ltd to expand its product portfolio with centrifuges offered by Koki Holdings.

Such activities boost the regional market growth.

The Asia Pacific is expected to grow during the forecast period due to the increasing demand for gene-based medicine and rising bioanalytical processes for clinical studies. Furthermore, the presence of various regional players with advanced product offerings and launches is expected to expand the regional growth during the forecast period.

• For instance, in June 2024, VFL Sciences, India, launched the GreatSpin range of centrifuges. These advanced centrifuges are designed for a wide range of applications in research and clinical laboratories for sample separation, cell culture, and others. Such launches promote the regional growth.

Key Players Covered

The global bioseparation systems market is fragmented, with a large number of regional and multinational players.

The report includes the profiles of the following key players:

• Thermo Fisher Scientific Inc. (U.S.)
• Agilent (U.S.)
• Sartorius AG (Germany)
• Shimadzu (Japan)
• Waters Corporation(U.S.)
• Cytiva (U.S.)
• 3M (U.S.)
• YMC CO., LTD. (Japan)
• Merck KGaA (Germany)
• Beckman Coulter, Inc.  (U.S.)

Key Industry Developments

• In June 2024, Cytiva launched Supor Prime sterilizing grade filters. It is used to achieve higher yields, reduce premature blockages, and limit the costs associated with filtration losses.
• In October 2020, Thermo Fisher Scientific Inc. launched the Gibco CTS Rotea Counterflow Centrifugation System. It is a closed-cell therapy processing system that enables cost-effective and scalable cell therapy development and manufacturing.