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Cleanroom HVAC Market Size, Share & COVID-19 Impact Analysis, By Type (Modular Cleanroom, Stick Built Cleanroom, Hybrid Cleanroom, and Others), By Product (Equipment, Consumables, and Services), By Ventilation (Turbulent and Unidirectional), By Application (Pharmaceutical and Medical Device Manufacturing, Hospital, Research Institution, Automotive, Food Processing and Packaging, Semiconductor, and Others), and Regional Forecast, 2023– 2030

Last Updated: July 01, 2024 | Format: PDF | Report ID: FBI107833



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The global cleanroom HVAC market size was valued at USD 50.16 billion in 2022. The market is projected to grow from USD 52.83 billion in 2023 to USD 82.10 billion by 2030, exhibiting a CAGR of 6.5% during the forecast period.

Cleanroom HVAC is a specially developed official workspace with a completely controlled environment with no or minimal concentration of particulate matter and contaminants in the stipulated confined spaces. These spaces are developed to create a favorable and effective environment for the efficient manufacturing operations of application industries. The cleanroom HVAC holds a certain degree of critical importance as cleanroom operators need to maintain complete control over specific aspects such as temperature, room pressure, dust particulate count, and humidity to create the required atmosphere and manufacturing environment.


Surging Demand for Cleanroom HVAC Solutions from Healthcare Sector Aided Market Growth Amid the Pandemic

The prolonged lockdown implemented by various countries, including India, China, the U.S., Italy, the U.K., and others is erecting challenges that impact organizations of all sizes concerning the availability of labor, transportation of products, and others.

For instance, in January 2021, the International Labor Organization (ILA) stated that in 2020, 8.8% of worldwide working hours (i.e., 255 million full-time jobs) were lost relative to the 4th quarter of 2019.

However, in December 2020, the European Central Bank (ECB), in its economic bulletin, encapsulated that the worldwide economy sharply dropped in the 1st quarter of 2020 and recovered in the 3rd quarter with continued growth. During the pandemic, there has been an increased demand for cleanrooms, especially in the healthcare and pharmaceutical industries, to ensure the safety of patients, healthcare workers, and the general public. This has led to increased demand for cleanroom HVAC systems to maintain the required cleanliness and air quality levels.


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Efforts by Manufacturers to Develop Energy-efficient Products to Attract Wide Range of Customers

Several factors, including rising energy costs, regulatory requirements, and growing awareness of the environmental impact of energy consumption, are driving the trend toward energy efficiency in the market.

One of the main ways companies are improving energy efficiency in cleanroom HVAC systems is through advanced controls and monitoring technologies and government aid in research and development activities. These technologies allow for more precise control of temperature, humidity, and airflow, which can help reduce energy consumption by ensuring that systems are only running when necessary and are operating at optimal levels.

In November 2021, the U.S. Department of Energy (DOE) announced a USD 20 million investment in research & development projects to improve manufacturing energy efficiency. One of the projects will focus on developing new HVAC technologies for cleanrooms and other critical environments, with the goal of reducing energy consumption by up to 50%.


Increased Demand in Biotechnology to Provide Substantial Market Growth

The growth of the biotechnology sector is a significant driver for the cleanroom HVAC market growth. The increasing demand for innovative medicines, advancements in biotechnology research, and the growing aging population further aid market expansion. Biotech facilities require cleanroom environments to maintain product quality and minimize the risk of contamination. This has led to a significant increase in the biotech industry's demand for cleanroom HVAC systems.

For instance, the efforts to introduce cleanroom technology in biotechnology sector will aid the integration of cleanrooms for biologics drugs manufacturing facilities. Biologics are complex drugs made from living organisms and require specialized manufacturing processes, including cleanroom environments.

The biotech sector is experiencing significant growth due to the increasing prevalence of chronic diseases, rising demand for personalized medicine, and advancements in gene editing and cell therapy technologies. As a result, there is a growing need for developing new and advanced biotech facilities that require cleanroom environments.

For instance, gene therapy is a promising field of biotechnology that aims to treat or cure genetic diseases by modifying or replacing genes. Gene therapy requires specialized cleanroom environments to maintain product quality and minimize the risk of contamination.


High Operating and Maintenance Costs of Cleanrooms to Hinder Market Expansion

Cleanrooms require specialized HVAC systems designed to maintain the required air quality and cleanliness levels, which can be expensive to operate and maintain. The operating costs of cleanrooms can be high due to the energy-intensive HVAC systems required to maintain the desired temperature, humidity, and air quality levels. In addition, the air filtration systems used in cleanrooms require regular maintenance and replacement of filters, which can also contribute to high operating costs.


By Type Analysis

Cost-effective Operations and Economic Installations to Augment Acceptance of Modular Cleanroom Segment

By type, the market is categorized into modular cleanroom, stick built cleanroom, hybrid cleanroom, and others (portable cleanroom). Modern cleanrooms provide hassle free installation and also have a simple and swift process of infrastructure establishment. Moreover, economical operational cost of these cleanrooms attract a wide array of customers toward modern cleanroom products. These types of cleanrooms are comparatively easier to integrate add-on components and replace components, which curtails maintenance cost of these facilities and stand out as a better return of investment alternative amongst all the aforementioned cleanrooms.

Stick built cleanroom segment is projected to maintain its satisfactory performance in the market after the modular cleanrooms segment. Global acceptance of stick-built cleanroom and availability of these products are responsible for decent growth prospects for the market.

By Product Analysis

Increasing Application of Single Use Disposable Products to Elevate Growth of Consumables

On the basis of product, the market is classified into equipment, consumables, and services (installation and maintenance). To provide holistic projection of the market numbers, we have cataloged equipment and consumables into further sub segments.

The equipment segment is categorized into fan filter units, laminar air flow systems, HEPA filters, air showers and diffusers, and others (desiccator cabinet). Moreover, the consumables segment is classified into apparels, gloves, wipes, vacuum systems, disinfectants, and others (cleaning products).

The consumables segment is expected to maintain a dominating share in the global market and is also anticipated to propel forward with a swift growth pace. Extensive use of cleanrooms and unprecedented increment in the application of disposal and single use apparels and gloves can be sighted as a primary contributing factor for making consumables a major segment in terms of market share.

The high cost associated with the HVAC systems and air showers and diffusers will provide a lion’s share for the above mentioned two segments throughout the forecast period. HVAC systems and air showers and diffusers can be termed as the most integral part of the cleanroom setup which also increases the sales of these products in the market. Additionally, apparels and gloves segments will collectively hold a major portion of the market share. The increasing importance of single use apparels and gloves during the operations of cleanrooms aids the sizable market share and fast-paced performance.

By Ventilation Analysis

Better Control Over Incoming Airborne Particulates to Fuel the Sales of Unidirectional Ventilation Systems

Based on ventilation, the market is split into turbulent and unidirectional. The unidirectional segment currently holds more than 70% of the market share and by the end of forecast period, the unidirectional segment is set to maintain healthy progress prospects in terms of market share. Robust and uniformity in air flow, complete control over the volume and speed of incoming air through the HVAC ventilation, and ability to maintain the ideal surroundings in testing and critical process handling area are flourishing the unidirectional ventilation growth.

By Application Analysis

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Development of Complex Environment to Manufacture High Quality Healthcare Products to Solidify Pharmaceutical And Medical Device Manufacturing Market Growth

On the basis of application, the market is classified into pharmaceutical and medical device manufacturing, hospital, research institution, automotive, food processing and packaging, semiconductor, and others (aerospace and defense, agriculture). Pharmaceutical and medical device manufacturing now requires extensive complexity and strict containment requirements. These necessities will attract installation of cleanrooms and will provide hefty share to the aforementioned segment in the global market.

Additionally, in terms of market growth semiconductor application is projected to develop at the most promising pace, the manufacturing of semiconductor chipsets and establishment of semiconductor manufacturing facilities across the developing countries in Asia Pacific is propelling the development prospects of the fastest growing semiconductor application in the global market.


Asia Pacific Cleanroom HVAC Market Size, 2022 (USD Billion)

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On the basis of region, the market is classified across North America, Europe, Asia Pacific, the Middle East and Africa, and South America.

Substantial surge in activities of end-use industries and continuous efforts by the governments across the developing economies to create a robust healthcare ecosystem can be considered as one of the pivotal factors behind the noteworthy Asia Pacific market share. Additionally, over the recent past, Taiwan, India, and a few ASEAN countries have emerged as a prominent manufacturer in the semiconductor industries and are striving to establish themselves as one of the key players in the market, thus prompting optimistic development of the region. Moreover, India is a domestic market to the biggest vaccine producer company across the globe. This phenomenon makes India a crucial country in the pharmaceutical industry, which is driving market augmentation.

North America is estimated to maintain its position as a second highest revenue generating region in the global market throughout the forecast period. The region is also set to emerge as a fastest growing region across all regions. The U.S. will majorly contribute to the cleanroom HVAC market share and is projected to attain favorable market growth. The strong presence of prominent manufacturers in North America is also aiding the growth of the market. Additionally, the implicit efforts of these companies regarding technological developments through strong investments in research and development operations, strategic partnerships, acquisitions, and entering into collaborations and joint ventures are identified as pivotal factors boosting the development potential of North America.

In terms of market development, the semiconductor and automotive segments are set to register a skyrocketing growth prospect. The exemplary performance of the European automotive sector spearheaded by Germany and current efforts of the European Union to encourage customers for adoption of electric vehicles are making inroads for the development of electric vehicle components in a high-tech manufacturing unit, thereby causing surge in demand for cleanroom HVAC in the automotive sector. Moreover, robust research initiatives undertaken by biopharma and gene cell therapy regeneration sectors in Europe are pushing market growth. Additionally, Europe is a pioneering region in terms of adoption of ultra-novel solutions and integration of high-end technology in their manufacturing process to develop superior and quality products. Augmented production for semiconductor devices, novel medical devices, and electric automotive vehicle component are generating demand for products that provide superior equipment – cost effective, ultra-modern technology integrated, and lesser carbon footprints for manufacturing.

South Africa is projected to develop at a noteworthy pace in the market whereas in terms of market share, GCC countries are estimated to account for a considerable portion of the regional market, owing to the heavy acceptance of modern cleanroom facilities and establishment of new cleanrooms in pharmaceutical and semiconductor manufacturing in diverse geographies within the region. The application of cleanrooms in the gene and cell therapy sector has been observed to develop at a critical rate over the forecast period, strengthening the market share of the pharma sector.


High Level of Fragmentation is Expected to Emerge as a Significant Challenge for Established Players

The global market is highly fragmented, with many local players operating in various regions across the world. The high fragmentation of the market is due to a variety of factors, including diverse requirements of different industries, varying regulations and standards across regions, and specialized nature of cleanroom HVAC systems. In addition, cleanroom systems require a high level of expertise and specialization owing to their complexity and critical importance in maintaining a sterile environment. This often leads to the emergence of smaller local players who focus on providing customized solutions to meet specific needs of their customers.

Moreover, the market has relatively low barriers to entry, allowing new players to enter the market easily. This has led to proliferation of small & medium-sized companies that specialize in providing specific cleanroom solutions. However, with increasing demand for cleanroom HVAC systems in various industries, including semiconductor, pharmaceuticals, biotechnology, and electronics, there is a trend toward consolidation in the market.



  • March 2023: Owen Greenings and Mumford (OGM) announced an investment of USD 602,040 to expand cleanroom in its manufacturing facility located in Oxford.

  • January 2022: AES Clean Technology, a manufacturer of cleanroom facilities invested USD 14.2 million to open a new manufacturing facility in Pennsylvania.

  • January 2022: Clean Rooms International Launched Flow-Thru Light Troffer, which is especially designed for cleanroom application. It is suitable for class 10 to class 100,000 environments.

  • May 2022: CWS Cleanrooms acquired STAXS, a distributor of cleanroom consumables for life sciences in Benelux region with an objective to add cleanroom consumables to its service portfolio.

  • July 2022: CWS Cleanrooms completed the acquisition of GOREX Gebäudemanagement GmbH, a Germany-based company specializing in cleanroom and laboratory cleaning.


An Infographic Representation of Cleanroom HVAC Market

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The report provides a detailed analysis of the market and focuses on key aspects such as leading companies and leading applications of the product. Besides, the report offers insights into the market trends and highlights key industry developments. In addition to the factors above, the report encompasses several factors that contributed to the growth of the market in recent years.

Report Scope & Segmentation



Study Period


Base Year


Estimated Year


Forecast Period


Historical Period


Growth Rate

CAGR of 6.5% from 2023 to 2030


Value (USD Billion)


By Type

  • Modular Cleanroom

    • Softwall Cleanroom

    • Hardwall Cleanroom

  • Stick Built Cleanroom

  • Hybrid Cleanroom

  • Others (Portable Cleanroom, etc.)

By Product

  • Equipment

    • HVAC Systems

    • Fan Filter Units

    • Laminar Air Flow Systems

    • HEPA Filters

    • Air Showers and Diffusers

    • Others (Desiccator Cabinet, etc.)

  • Consumables

    • Apparels

    • Gloves

    • Wipes

    • Vacuum Systems

    • Disinfectants

    • Others (Cleaning Products, etc.)

  • Services (Installation and Maintenance)

By Ventilation

  • Turbulent

  • Unidirectional

By Application

  • Pharmaceutical and Medical Device Manufacturing

  • Hospital

  • Research Institution

  • Automotive

  • Food Processing and Packaging

  • Semiconductor

  • Others (Aerospace and Defense, Agriculture, etc.)

By Region

  • North America (U.S., Canada, and Mexico)

  • South America (Brazil, Argentina, and Rest of South America)

  • Europe (U.K., Germany, France, Italy, Russia, and Rest of Europe)

  • Asia Pacific (China, India, Japan, South Korea, Australia, Indonesia, Thailand, Malaysia, Philippines, Vietnam, and Rest of Asia Pacific)

  • Middle East and Africa (Turkey, GCC, South Africa, and Rest of Middle East and Africa )

Frequently Asked Questions

As per the Fortune Business Insights study, the market size was USD 50.16 billion in 2022.

The market is likely to grow at a CAGR of 6.5% over the forecast period (2023-2030).

The pharmaceutical and medical device manufacturing segment is expected to hold a substantial share in the market due to increasing complex operations in biopharma manufacturing.

The market size in Asia Pacific stood at USD 19.40 billion in 2022.

Increased demand of cleanrooms in biotechnology is anticipated to drive the market.

Some of the top players in the market are Ardmac, iCLEAN Technologies, and Airtech Japan.

Asia Pacific dominated the market in terms of sales in 2022.

High operating and maintenance costs of cleanrooms are hindering the market growth.

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