Endoscopic Submucosal Dissection Market Size, Share & Industry Analysis By Product Type (Gastroscopes & Colonoscopes, Knives, Injection Agents, Tissue Retractors, Graspers/Clips, and Others), By Indication (Colon Cancer, Esophageal Cancer, Stomach Cancer, and Others), By End-user (Hospitals & ASCs, Specialty Clinics, and Others), and Regional Forecast, 2026-2034

The global endoscopic submucosal dissection market is experiencing significant growth due to the increasing demand for cancer removal surgeries in the gastrointestinal tract and advancements in endoscopic submucosal dissection devices and accessories, which are expected to support its adoption in the forthcoming years. As a result, key players are expanding their product portfolios and reach in both developed and developing countries worldwide.

Endoscopic Submucosal Dissection Market Driver

Rising Incidence of Gastrointestinal (GI) Cancers to Propel the Market Growth

Over the past few years, there has been a rise in the incidence of gastrointestinal cancers globally. This is driving the increase in screening and early-detection programs, which in turn is fueling the demand for minimally invasive treatments such as endoscopic submucosal dissection (ESD). These procedures shorten the recovery period compared to open surgery, which is driving their adoption and spurring market growth.

• For instance, according to data published by the National Center for Biotechnology Information (NCBI) in March 2022, around 1.1 million new cases of stomach cancer were diagnosed in 2020 worldwide.

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According to data published by the American Cancer Society, Inc., around 107,320 new cases of colon cancer were reported in 2025.

Endoscopic Submucosal Dissection Market Restraint

Shortage of Skilled Professionals to Hinder the Market Growth

ESD procedures require advanced endoscopic skills, precise control, deep knowledge of GI tract anatomy, and experience, particularly for the colon and esophagus. In several emerging and low-income countries, there is a shortage of such professionals, leading to delays that limit procedure volumes and restrict market growth.

• For instance, according to the Health Ministry Report 2024, there was a 70.0% shortage of specialists, including GI surgeons, in rural India.

Endoscopic Submucosal Dissection Market Opportunity

Increasing Adoption of ESC in Developing Regions to Offer Lucrative Growth Opportunity

In recent years, there has been a growing adoption of ESD in developing countries, including India, China, Brazil, and South Korea. Improvements in healthcare infrastructure and a rising awareness of ESD among clinicians in these countries support this. Such a scenario is anticipated to offer lucrative opportunities for key players to expand their product offerings in these countries.

Segmentation

Key Insights

The report covers the following key insights:

• Incidence of Key Cancer, by Key Country/Region, 2025
• Advancements in Endoscopic Submucosal Dissection Devices
• Key Industry Developments - (Mergers, Acquisitions & Partnerships, and Others)

Analysis by Product Type

Based on product type, the market is fragmented into gastroscopes & colonoscopes, knives, injection agents, tissue retractors, graspers/clips, and others.

The gastroscopes & colonoscopes segment is expected to account for the largest market share during the forecast period. Gastroscopes & colonoscopes are primary capital equipment required for every ESD procedure. Their demand is driven by upgrades from standard to high-resolution or magnification scopes. In response, hospitals are replacing aging systems, expanding endoscopy units and adding ESD capabilities.

• For instance, in July 2023, the American Society for Gastrointestinal Endoscopy’s (ASGE) guidelines emphasized the use of ESD for early GI lesions, indirectly increasing the demand for advanced gastroscopes and colonoscopes in U.S. centers.

Analysis by Indication

By indication, the market is categorized into colon cancer, esophageal cancer, stomach cancer, and others.

The diagnostics segment is expected to hold a significant share during the forecast period. In East Asia, the early gastric cancer screening is significantly higher. Moreover, the high en bloc resection rates and excellent outcomes are driving strong adoption of ESD, which is anticipated to drive the segment’s growth during the forecast period.

Analysis by End-user

By end-user, the market is segmented into hospitals & ASCs, specialty clinics, and others.

The hospitals & ASCs segment held the largest market share in 2025.  The growth is due to the high volume of endoscopic submucosal procedures performed in hospitals as well as ASCs. Moreover, the significant growth in the number of ASCs is also contributing to this increasing volume, driving the adoption of ESD devices.

• For instance, according to data from the Ambulatory Surgery Center Association (ASCA), as of March 2025, there were over 6,500 ambulatory surgery centers in the U.S.

Regional Analysis

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On the basis of geography, the market has been studied across Europe, North America, Latin America, Asia Pacific, and the Middle East & Africa.

North America held the largest global endoscopic submucosal dissection market share in 2025. The growth is attributed to the high incidence of GI cancer surgery in the region, which contributes to the high adoption of ESD devices. Moreover, the availability of major players in the U.S. and Canada is additionally contributing to the high penetration of these devices in the region.

Asia Pacific is expected to grow at the highest CAGR over the forecast period. The growth is attributed to the focus of key players on opening new manufacturing sites in the region, driven by the high incidence of GI cancers. Moreover, the increasing aging population and high smoking rate are increasing the prevalence of such cancers in the region, driving ESD surgery volumes.

• For instance, according to the Tobacco Prevention and Cessation Volume 7 in March 2021, the overall prevalence of smoking tobacco in India was 10.38%, while smokeless tobacco usage stands at 21.38%.

Key Players Covered

The global endoscopic submucosal dissection market is fragmented, with key companies focusing on expanding their product reach globally through partnerships, collaborations, and launches, which is expected to help them gain a significant share of the market.

The report includes the profiles of the following key players:

• Olympus Corporation (Japan)
• FUJIFILM Holdings Corporation (Japan)
• Boston Scientific Corporation (U.S.)
• Cook (U.S.)
• Medtronic (Ireland)
• KARL STORZ (Germany)
• Elektromedizin GmbH (Germany)
• PENTAX Medical (Japan)
• CONMED Corporation (U.S.)
• Ovesco Endoscopy AG (Germany)

Key Industry Developments

• January 2023: FUJIFILM Holdings Corporation launched ClutchCutter and FushKnife for therapeutic gastrointestinal applications at the 63rd Annual Conference of the Indian Society of Gastroenterology-ISGCON, Jaipur.
• April 2022: FUJIFILM Holdings Corporation launched Tracmotion, a Red Dot Award-winning Endoscopic Submucosal Dissection device, at Endocon 2024 in Delhi, enhancing precision and efficiency in gastroenterology procedures.