Acute Bacterial Skin And Skin Structure Infections (ABSSSI) Treatment Market Size, Share and Industry Analysis By Infection Type (Hospital-acquired ABSSSI, Community-acquired ABSSSI), By Route of Administration (Oral, Parenteral), By Distribution Channel (Hospitals Pharmacy, Retail Pharmacy, Online Pharmacy) and Regional Forecast 2025-2032

The global acute bacterial skin and skin structure infections (ABSSSI) treatment market size was valued at USD 12.50 billion in 2024. The market is projected to grow from USD 13.68 billion in 2025 to USD 25.66 billion by 2032, Exhibiting a CAGR of 9.4% during the forecast period (2024-2032). North America dominated the acute bacterial skin and skin structure infections treatment market with a market share of 45.6% in 2024.

Acute bacterial skin and skin structure infections are referred to as bacterial infection of the skin and associated tissues. These infections can be complicated skin infections or uncomplicated skin infections.

Antibiotics are used for the treatment of skin and skin structure infections but an increase in antimicrobial resistance between gram-positive and negative bacteria with methicillin-resistant Staphylococcus aureus has become quite challenging in treating ABSSSI. So, the development of novel drugs to fight against resistant microbes is the need of the hour.

Additionally, the prevalence of bacterial skin infections is rising in emerging nations such as China, India, and some regions of Latin America and Middle East & Africa. Extensive research in the development of new treatment options and a huge number of potential pipeline drugs in late and mid-stage development are anticipated to create a profitable environment for acute bacterial skin and skin structure infections treatment market growth during the forecast period.

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"Unmet needs in the treatment of acute bacterial skin and skin structure infections (ABSSSI) globally, is driving the demand for anti-MRSA treatment options in the market."

Growing economic burden of aucte bacterial skin and skin structure infections (ABSSSI) including direct and indirect cost of treatment, along with prolonged treatment duration and lack of effective drugs in treating skin infections, has presented significant unmet needs in the global acute skin and skin structure infections (ABSSSI) treatment market growth. This is providing huge opportunities for major players to enter the ABSSSI treatment market by introducing new drugs against MRSA, with an aim to fight the resistant bacteria thus lowering the economic burden of the treatment cost. This coupled with increasing prevalence of hospital-acquired ABSSSI and demand for effective drugs, will fuel the ABSSSI treatment market growth in the future.

Global Acute Bacterial Skin and Skin Structure Infections Treatment Market Overview

Market Size & Forecast:

• 2024 Market Size: USD 12.50 billion
• 2025 Market Size: USD 13.68 billion
• 2032 Forecast Market Size: USD 25.66 billion
• CAGR: 9.4% (2025–2032)

Market Share:

• North America led the global ABSSSI treatment market with a 45.6% share in 2024, driven by intensive R&D activities, rapid adoption of novel anti-MRSA drugs, and strong presence of leading pharmaceutical companies.
• By Infection Type, Hospital-Acquired ABSSSI is anticipated to be the fastest-growing segment, owing to rising cases of MRSA-resistant infections and the increasing burden of healthcare-associated infections.
• By Route of Administration, Parenteral segment dominated the market in 2024, due to superior therapeutic efficacy, faster action against resistant bacteria, and increasing penetration of advanced injectable formulations.

Key Country Highlights:

• United States: The largest revenue-generating country, driven by strong pipeline development, regulatory approvals, and increasing incidence of MRSA-associated ABSSSI cases. Major pharmaceutical players like Merck & Co. and Pfizer dominate the landscape.
• Europe: Holds the second-largest share due to rising antimicrobial resistance surveillance programs, early adoption of novel therapeutics, and favorable reimbursement structures.
• Asia Pacific: Expected to register the highest CAGR during the forecast period, supported by increasing prevalence of skin infections, improving healthcare infrastructure, and growing awareness of ABSSSI treatment options in countries like China and India.
• Latin America & Middle East & Africa: Currently smaller in market share but anticipated to grow steadily due to rising infection rates, increased access to advanced therapeutics, and efforts to combat antimicrobial resistance.

Market Segmentation

Hospital-acquired ABSSSI are caused upon admission to a hospital that was not present in the patient before hospitalization. These infections have become a tremendous concern to healthcare providers as they are among the top causes of death worldwide. Methicillin-resistant Staphylococcus aureus (MRSA) been the cause for most infections as well as the growing resistance against this bacterium is leading to the rise of hospital acquired acute bacterial skin and skin structure infections Community-acquired ABSSSI accounted for a significant market share in 2024. Among the infection type, hospital-acquired ABSSSI is anticipated to be the fastest growing segment during the forecast period.

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On the basis of route of administration, the global acute bacterial skin and skin structure infections treatment market segments include oral and parenteral. The parenteral route accounted for maximum share in 2024 owing to penetration of novel products against the resistance of MRSA, therapeutic benefits offered by parenteral treatment, and shorter curative time as compared to oral administration. On the basis of distribution channel, the market segments include hospital pharmacy, retail pharmacy and online pharmacy.

Regional Analysis

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"Extensive R&D and New Product Launch Enables North America to Hold a Higher Share in the Global acute bacterial skin and skin structure infections treatment Market"

North America generated an acute bacterial skin and skin structure infections treatment market revenue of USD 5.70 Billion and is expected to dominate the market throughout the forecast period.  Focus on extensive research activity by the top pharmaceutical companies in the development of anti-MRSA drugs for ABSSSI treatment and novel product launch is responsible for the generation of higher ABSSSI treatment market revenue.

Moreover, approval of several pipeline candidates is also responsible for driving the North America acute bacterial skin and skin structure infections treatment market during the forecast period. Europe holds the second position in terms of market revenue for the year 2018. Asia Pacific acute bacterial skin and skin structure infections treatment market is anticipated to witness a higher CAGR during the forecast period.

Key Market Drivers

"Merck & Co., Inc and Pfizer Inc., to Account for Maximum Market Share in Terms of Revenue"

Merck & Co., Inc is a leading player in the global acute skin and skin structure infections treatment market. Merck & Co., Inc is expected to retain its position in the forecast period owing to its acquisitions of companies manufacturing ABSSSI drugs responsible for increasing Merck’s product portfolio, efficient customer reach, and strong brand presence. This company, together with Pfizer Inc., currently accounts for maximum market share in terms of  ABSSSI treatment market revenue. Other players operating in the global ABSSSI treatment market are MELINTA THERAPEUTICS, INC., ALLERGAN, Paratek Pharmaceuticals, Inc., and Others.

List of Companies Profiled

• Merck & Co., Inc.
• Pfizer Inc.
• MELINTA THERAPEUTICS, INC.
• ALLERGAN
• Paratek Pharmaceuticals, Inc.
• Cumberland Pharmaceuticals Inc.
• Teva Pharmaceutical Industries Ltd.
• Other prominent players

Report Coverage 

The ABSSSI are bacterial skin infections having a minimum lesion surface area of 75 cm². Typical bacterial pathogens responsible for the cause of acute bacterial skin and skin structure infections are Streptococcus pyogenes and Staphylococcus aureus including methicillin-resistant S. aureus.

The treatment include antibacterials like vancomycin, dalbavancin, oritavancin, linezolid, clindamycin, daptomycin, and others. Increasing prevalence of MRSA associated ABSSSI and unmet demands in emerging nations is expected to significantly drive the global acute bacterial skin and skin structure infections treatment market revenue during the forecast period.

The report provides qualitative and quantitative insights on the ABSSSI treatment industry trends and detailed analysis of market size and growth rate for all possible segments in the market. The ABSSSI treatment market segments include infection type, route of administration and distribution channel.

On the basis of infection type, the global acute bacterial skin and skin structure infections (ABSSSI) treatment market is further segmented into hospital-acquired ABSSSI and community-acquired ABSSSI. On the basis of the route of administration, the global market is segmented into oral and parenteral.  

On the basis of distribution channel, the global acute bacterial skin and skin structure infections treatment Industry is segmented into hospital pharmacy, retail pharmacy and online pharmacy. Geographically, the ABSSSI treatment market is segmented into five major regions, which are North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. The regions are further categorized into countries. 

Along with this, the report on global acute bacterial skin and skin structure infections treatment market analysis comprises of market dynamics and competitive landscape. Additionally, the report offers insights on the prevalence of bacterial skin infections in key countries, new product launch, pipeline analysis, and recent industry developments such as mergers & acquisitions.

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SEGMENTATION

Key Industry Developments

•   In February 2019, Paratek Pharmaceuticals, Inc., launched NUZYRA intravenous and oral antibiotic in the treatment of ABSSSI.
•   In January 2018, Melinta Therapeutics, Inc., launched BAXDELA for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI).
•   In May 2016, Allergan, launched TEFLARO an antibiotic for the treatment of acute bacterial skin and skin structure infections (ABSSSI).