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Diabetic peripheral neuropathy is referred as the damage of nerves, which is caused due to excessive blood sugar and diabetes. There are certain types of diabetic neuropathy such as peripheral neuropathy, proximal neuropathy, autonomic neuropathy, and focal neuropathy. Loss of sensations, acute pains or cramps, muscle weakness, loss of reflexes, and loss of balance are some of the commonly observed symptoms of diabetic peripheral neuropathy amongst others. According to the American Diabetes Association, an estimated 50.0% of diabetes patients suffer from neuropathy each year in the U.S.
At the initial phase of diabetic peripheral neuropathy, the pain is not severe, hence over the counter drugs are recommended for the treatment of initial phase of diabetic peripheral neuropathy. Currently, acetaminophen, non-steroidal anti-inflammatory drugs, and anti-depressants are widely prescribed by the physicians for the treatment of diabetic peripheral neuropathy.
Pharmaceutical companies and other drug manufacturers are prominently focusing on studying and developing new treatment options for diabetic peripheral neuropathy. For instance; ABX-1431, which is being studied by Abide Therapeutics, is currently in phase-1 clinical trials to check its efficacy and tolerability for the treatment of diabetic peripheral neuropathy.
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At present, around 75% of the pipeline candidates for diabetic peripheral neuropathy are in the phase-2 and phase-3 stage. Majority of the studies have been sponsored by pharmaceutical companies and other drug manufacturers.
The report on ‘Diabetic Peripheral Neuropathy – Pipeline Review, 2019’ provides a comprehensive overview of the drugs that are in the R&D pipeline by indication or molecule for Diabetic Peripheral Neuropathy. The report provides a thorough analysis of the distribution of the pipeline products by clinical trial stage, indication, company, therapy area and details such as clinical trial stage, sponsor, description on every product in the pipeline.
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