"Designing Growth Strategies is in our DNA"
Dravet syndrome is referred to as a severe type of epilepsy that is characterized by the often triggering through the occurrence of fevers or high temperature. Dravet syndrome is an extremely rare dysfunction of the brain and is often a lifelong condition. The time of the onset of the disease is the first year of childhood in an otherwise healthy infant, and as time progresses, several other types of seizures occur.
According to the Dravet Foundation, it was determined that the Dravet syndrome occurs in 1 in 15,700 infants born in the U.S. The Food and Drug Administration (FDA) approval of stiripentol (Diacomit) for the treatment of patients suffering from the Dravet syndrome aged two years and older and are already taking clobazam.
To gain extensive insights into the market, Request for Customization
In June 2018, the FDA also approved epidiolex (cannabidiol), the first FDA approved drug containing a purified drug substance derived from marijuana. These recent approvals are further contributing to the accelerated growth of the market, due to the greater research & development efforts being undertaken. These factors are anticipated to contribute to the positive Dravet syndrome market growth.
One of the key market drivers of the Dravet syndrome market growth is the recent regulatory approvals for the treatment and management of the disorder. Some of the recent regulatory approvals include stiripentol (Diacomit) and also epidiolex for the management of a variety of symptoms associated with the disorder.
At the same instance, several newer applications for the regulatory approval such as the submission of a new drug application (NDA) by Zogenix for its drug candidate ZX008 (Fintepla), is also anticipated to contribute towards the accelerated growth of the market. Apart from these, several drug candidates are also undergoing clinical trials at various stages.
The factor that is expected to inhibit the growth of the market is the adverse effects associated with Dravet syndrome products. For instance, some of the side effects include increased drowsiness, agitation, impaired coordination, loss of muscle tone, nausea, depressive thoughts, and feelings, amongst others. This may make the medications unsuitable for some kinds of patients. Regulatory and clinical hurdles might also impact the global Dravet syndrome market growth due to delays in product approvals.
The major companies covered in the global Dravet syndrome market report include Epygenix Therapeutics, Inc., Ovid Therapeutics, GW Pharmaceuticals plc., Takeda Pharmaceutical Company Limited., Zogenix and PTC Therapeutics, and other players.
· Vagus Nerve Stimulation (VNS)
By Distribution Channel
· Hospital Pharmacies
· Retail Pharmacies
· Online Pharmacies
· North America (USA and Canada)
· Europe (UK, Germany, France, Italy, Spain, Scandinavia and Rest of Europe)
· Asia Pacific (Japan, China, India, Australia, Southeast Asia and Rest of Asia Pacific)
· Latin America (Brazil, Mexico and Rest of Latin America)
· Middle East & Africa (South Africa, GCC and Rest of Middle East & Africa)
As per the current Dravet syndrome market trends, at present, drugs account for the largest proportion of the market, and this is because of the recent regulatory approvals and the majority of the treatment options consisting of drugs of classes of anticonvulsants, benzodiazepines, cannabinoids, and others. Vagus Nerve Stimulations (VNS) are also approved as a form of treatment, and in some instances, there are used in patients who do not respond to medications alone.
The global Dravet Syndrome market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America followed by Europe, are the two largest markets for Dravet Syndrome at present, and they are expected to account for a large proportion of the market in the forecast period as well. In 2018, the Food and Drug Administration (FDA) approved stiripentol and epidiolex, for the treatment of the Dravet syndrome. In the Asia Pacific region, Japan is expected to provide the largest market opportunity. This is due to the increased awareness of the disorder, the ongoing R&D efforts, and the prevalence of the disorder in the country. Additionally, Dravet Syndrome market in Latin America and the Middle East and Africa is in the nascent stage; however, unmet needs for Dravet syndrome treatment is expected to drive the market growth in this region.
“This report is really well done and we really appreciate it! Again, I may have questions as we dig in deeper. Thanks again for some really good work.”- U.S.-based biotechnology company focussing on treatment of chronic pain.
“Kudos to your team. Thank you very much for your support and agility to answer our questions.”- Europe-based provider of solutions to automate data centre operations.
“We appreciate you and your team taking out time to share the report and data file with us, and we are grateful for the flexibility provided to modify the document as per request. This does help us in our business decision making. We would be pleased to work with you again, and hope to continue our business relationship long into the future.”- India-based manufacturer of industrial and specialty intermediates with a strong global presence.
“I want to first congratulate you on the great work done on the Medical Platforms project. Thank you so much for all your efforts.”- One of the largest cosmetics company in the world.
“Thank you very much. I really appreciate the work your team has done. I feel very comfortable recommending your services to some of the other startups that I’m working with, and will likely establish a good long partnership with you.”- U.S. based startup operating in the cultivated meat market.
“We received the below report on the U.S. market from you. We were very satisfied with the report.”- UGlobal hearing aids manufacturer.
“I just finished my first pass-through of the report. Great work! Thank you!”- U.S. based solar racking solutions provider.
“Thanks again for the great work on our last partnership. We are ramping up a new project to understand the imaging and imaging service and distribution market in the U.S.”- World’s leading advisory firm.
“We feel positive about the results. Based on the presented results, we will do strategic review of this new information and might commission a detailed study on some of the modules included in the report after end of the year. Overall we are very satisfied and please pass on the praise to the team. Thank you for the co-operation!”- Germany based machine construction company.
“Thank you very much for the very good report. I have another requirement on cutting tools, paper crafts and decorative items.”- Japanese manufacturing company of stationery products.
“We are happy with the professionalism of your in-house research team as well as the quality of your research reports. Looking forward to work together on similar projects”- One of the Leading Food Companies in Germany
“We appreciate the teamwork and efficiency for such an exhaustive and comprehensive report. The data offered to us was exactly what we were looking for. Thank you!”- Intuitive Surgical
“I recommend Fortune Business Insights for their honesty and flexibility. Not only that they were very responsive and dealt with all my questions very quickly but they also responded honestly and flexibly to the detailed requests from us in preparing the research report. We value them as a research company worthy of building long-term relationships.”- Major Food Company in Japan
“Well done Fortune Business Insights! The report covered all the points and was very detailed. Looking forward to work together in the future”- Ziering Medical
“It has been a delightful experience working with you guys. Thank you Fortune Business Insights for your efforts and prompt response”- Major Manufacturer of Precision Machine Parts in India
“I had a great experience working with Fortune Business Insights. The report was very accurate and as per my requirements. Very satisfied with the overall report as it has helped me to build strategies for my business”- Hewlett-Packard
“This is regarding the recent report I bought from Fortune Business insights. Remarkable job and great efforts by your research team. I would also like to thank the back end team for offering a continuous support and stitching together a report that is so comprehensive and exhaustive”- Global Management Consulting Firm
“Please pass on our sincere thanks to the whole team at Fortune Business Insights. This is a very good piece of work and will be very helpful to us going forward. We know where we will be getting business intelligence from in the future.”- UK-based Start-up in the Medical Devices Sector
“Thank you for sending the market report and data. It looks quite comprehensive and the data is exactly what I was looking for. I appreciate the timeliness and responsiveness of you and your team.”- One of the Largest Companies in the Defence Industry