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Vitiligo is a type of skin disease in which melanocytes, the pigment cells of the skin are destroyed, resulting in loss of skin colour or depigmentation in different areas of the body. The rate and extent of colour loss from vitiligo varies from patient to patient and can affect people of any age group. The disease can also affect the hair, eyes, and inside of the mouth. The disease can be triggered by events such as stress, sunburn or exposure to certain chemicals, or any disorder of the immune system that attacks the melanocytes.
Current treatment of vitiligo includes use of sunscreen, phototherapy, corticosteroids and drugs that affects the immune system. Calcipotriene, a form of vitamin D for topical application, can be used along with corticosteroids and light treatment. Also, ointment which contain tacrolimus or pimecrolimus, drugs can be effective on smaller patches of depigmented skin as they are calcineurin inhibitors.
Many pharmaceutical giants and academic research institutes are focusing on the development of novel treatment for vitiligo. For instance; PF-06651600, which is being studied by Pfizer Inc. is currently in phase 2 clinical trials to evaluate the safety and efficacy of PF-06651600 in the treatment of active non-segmental vitiligo.
At present, around 44% of the pipeline candidates for vitiligo are in the phase 2 stage. More than half of the studies are sponsored by academic and research institutes.
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The report on ‘Vitiligo – Pipeline Review, 2019’ provides a comprehensive overview of the drugs that are in the R&D pipeline by indication or molecule for Vitiligo. The report provides a thorough analysis of the distribution of the pipeline products by clinical trial stage, indication, company, therapy area and details such as clinical trial stage, sponsor, description on every product in the pipeline. Products in the preclinical and clinical stage along with dormant & discontinued pipeline candidates are included in the report. The report also covers additional insights such as epidemiology overview and current market scenario for Vitiligo.
The report on ‘Vitiligo – Pipeline Review, 2019’, which is built by following a robust research methodology involving primary interviews and desk research, provides a complete overview of the R&D activity and pipeline products to assist companies in developing growth strategies and identifying emerging players.