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Protease Enzyme Market Size, Share & Industry Analysis, By Source (Plant, Animal, Microbial), By Application (Cardiovascular, Oncology, Autoimmune, Skin Disorders, Orthopedics, Others), By End User (Hospitals & Specialty Clinics, Academic & Research Institutes, Pharmaceutical & Biotechnology Industries) and Regional Forecast, 2024-2032

Region :Global | Report ID: FBI103121 | Status : Ongoing



A protease, also called a peptidase or proteinase, is an enzyme that catalyzes proteolysis - a process of breakdown of proteins into smaller polypeptides or single amino acids. Based on the catalytic types the protease enzymes are categorized into serine, cysteine, aspartic, and metallo proteases. Protease enzymes are used in food industry, detergent industry and as well as in healthcare research. Protease enzyme is an organic ingredient and serves as an excellent alternative to chemical additives. Protease enzymes are used in pharmaceutical industries in larger quantities in order to treat multiple disorders associated with the heart, lungs, digestive tract, eye abnormalities, soreness and skin ulcers. The adoption of advanced technologies in the pharmaceutical industries is one of the major factor rising the adoption of protease enzyme application and hence driving the market growth.

Rising prevalence of cardiovascular disorders such as myocardial infraction, acute coronary syndrome and others is one of the major factor rising the demand for the protease enzyme based drugs and therapies for the treatment. Hence anticipated to drive the growth of the market during the forecast period of 2020-2027. Additionally, the protease enzymes are used to for the scar tissue repair and osteoarthritis. Rising prevalence of osteoarthritis is subsequently rising demand for the treatment and hence anticipated to drive the growth of the market. For instance, in United States the prevalence of osteoarthritis in adults above 60 year of age is approximately 12.0%. Additionally, according to the JMSCR, the osteoarthritis prevalence in India 22.0% to 39.0% of the total population. Bromelain is derived from the group of digestive enzymes and is approved treatment for osteoarthritis. These are some of the factors driving the growth of the protease enzyme market.

However, lack of FDA approvals for protease enzymes-based treatments, and lengthier process for the manufacturing of protease enzyme-based drugs and therapies leading to high cost of final products, are some of the major factors expected to hamper the market growth.

Up Arrow

Key Market Driver -

Rising prevalence of osteoarthritis, cardiovascular disorders

Down Arrow

Key Market Restraint -

Lack of FDA approvals

Market Segmentation:

Globally, the protease enzyme market is segmented on basis of source, application, end user and region. Based on the source, the market is segmented into plant, animal and microbial. Based on the application, the market is classified into cardiovascular, autoimmune, oncology, skin disorders, orthopedics and others. Based on the end user, the market is segmented into hospitals & specialty clinics, academic & research institutes, and pharmaceutical & biotechnology industries. Geographically, the Protease Enzyme market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East and Africa.

Key Players Covered:

The major companies in the global protease enzyme market Blirt.eu, Merck KGaA, Bio-Rad Laboratories, Inc, R&D Systems, Inc., Agilent Technologies, Inc., Novus Biologicals, Thermo Fisher Scientific Inc., and others.

Key Insights:

  • Prevalence of Key Disease Conditions, By Key Regions/ Key Countries, 2019

  • Pipeline Analysis, Key Players

  • New Product Launches

  • Key Industry Developments such as Mergers & Acquisitions

Regional Analysis:

Geographically, the protease enzyme market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the market owing rising prevalence of cardiovascular and orthopedic disorders, and increasing number of regulatory approvals for enzyme-based treatment and therapies. Europe is the second-largest contributor to the market owing to rising awareness among people regarding biological treatments, and increased healthcare expenditure. Additionally, increased investment by key market players in the development of protease enzyme-based treatment is one of the additional factor anticipated to propel the growth of the market in the region. Asia Pacific is anticipated to experience moderate growth in the market owing to rise in geriatric population, an increase in healthcare awareness, and an increase in government initiatives towards the healthcare sector. Latin America and Middle East are also anticipated to grow at a significant CAGR during the forecast period of 2020-2027.

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By Source

  • Plant

  • Animal

  • Microbial

By Application

  • Cardiovascular

  • Oncology

  • Autoimmune

  • Skin Disorders

  • Orthopedics

  • Others

By End User

  • Hospitals & Specialty Clinics

  • Academic & Research Institutes

  • Pharmaceutical & Biotechnology Industries

By Geography

  • North America (USA, Canada)

  • Europe (UK, Germany, France, Italy, Spain, Scandinavia, and Rest of Europe)

  • Asia Pacific (Japan, China, India, Australia, Southeast Asia, and Rest of Asia Pacific)

  • Latin America (Brazil, Mexico, Rest of Latin America)

  • Middle East & Africa (South Africa, GCC, and Rest of Middle East & Africa)

Protease Enzyme Industry Developments

  • In October 2019, Vericel Corporation and MediWound Ltd., initiated NexoBrid extended treatment to treat burnt patients with deep partial- and full-thickness burns in the U.S.

  • Ongoing
  • 2023
  • 2019-2022

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