Super-resolution Microscope Market Analysis Size, Share & Analysis By Technology (Structured Illumination Microscopy (SIM), Stimulated Emission Depletion (STED) Microscopy, and Stochastic Optical Reconstruction Microscopy (STORM)/Photoactivation Localization Microscopy (PALM)), By Application (Neuroscience, Oncology, Virology, and Others), and Regional Forecast, 2024-2032

Super-resolution microscopy (SRM) includes multiple techniques that achieve higher resolution than traditional light microscopy. It delivers a similar visualization as an optical fluorescence microscope and diffraction-limited resolution to analyze the cellular sample. SRM approaches can achieve a resolution of around 20 times greater than that of conventional light microscopy.

The increasing application of super-resolution microscope in research studies, technological advancements in SRM, and the increasing emphasis on nanotechnology have been boosting the super-resolution microscope market growth. Furthermore, these microscopes are extensively used for imaging cancer pathobiology and has significant efficiency in the clinical diagnosis of acute kidney injuries.

• In July 2019, a research study by NCBI stated that a super-resolution microscope played an important role in clinical diagnosis and cancer's pathogenesis for detecting tissue architecture and nuclear morphology of mutant genes. Increasing application of these microscopes for the diagnosis of various diseases has been increasing its adoption.


• Similarly, in December 2021, an article by the American Society of Nephrology stated that super-resolution microscopes could optimize the mitochondrial morphology in the human biopsy specimen, which is a valuable tool in the clinical diagnosis of acute kidney injuries.


• Additionally, in August 2019, according to the article published by ACS Publication, super-resolution microscopy played a crucial role in nano-medicine research by enabling the visualization of nanostructure in vitro and analyzing the characterization of their structure & nano-bio interaction of molecules. 

However, there are certain limitations associated with a Super-resolution microscope that can limit market growth.  For instance, Vibration and spherical aberration in these microscopes cause hindrance in higher resolution.

Impact of COVID-19 on the Super-resolution Market 

The sudden outbreak of COVID-19 had slowed the super-resolution microscope market growth. During the first half of 2020, the sale of super-resolution microscopes declined due to the lockdown restriction and supply-side chain disruption. Moreover, research activities other than COVID-19 were postponed in order to control the spread of COVID-19 which slowed its adoption. Guidelines by the government in order to control the pandemic created a massive reduction in patient visits to diagnostic laboratories and hospitals across the globe, which further limited the installation of super-resolution microscopes during the pandemic period. However, during the second half of 2020 adoption of super-resolution microscopes increased in the research studies for the development of COVID-19 vaccines and for the virus diagnosis.

• For instance, in February 2022, according to the News Medical Life Sciences article, super-resolution microscopes were used to study detailed inner structure of the human coronavirus genome within the host cell for detection of COVID-19.

The increased demand for super-resolution microscopes in research and development for COVID-19 diagnosis, treatment, and prevention boosted the global super-resolution market growth. 

Key Insight

• Technological Advancements in Super-resolution Microscope.


• Key industry development.


• Impact of Covid-19 on Super-resolution Microscopes Market.

Analysis by Technology

On the basis of technology, the market is segmented into structured illumination microscopy (SIM), stimulated emission depletion (STED) microscopy, and stochastic optical reconstruction microscopy (STORM)/photoactivation localization microscopy (PALM). Stimulated emission depletion (STED) segment accounted for a significant proportion of the global super-resolution microscope market in 2021, due to its extensive application in research studies increasing its adoption in academic and research institutes.

Whereas the stochastic optical reconstruction microscopy (STORM) segment is expected grow at a significant CAGR during the forecast period. The growth of the segment is attributed to its application in the study of detailed cellular structures such as mitochondria, epithelial cell, and others, which is used for the diagnosis and detection of various disease.

• For instance, in June 2020, according to the NCBI article, stochastic optical reconstruction microscopy (STORM) played a significant role in diagnosing early cancer by detecting of the disruption of chromatin structure which initiated carcinogenesis by malignant transformation.


• Moreover, in August 2018, according to an article by News Medical Life Science, stimulated emission depletion (STED) microscopy was used in biomedical research as it can enable high-resolution imaging beyond the diffraction limit of other microscopes delivering detailed visualization of the required sample. The increasing application of STED in biomedical research is expected to contribute to market growth.

Whereas, structured illumination microscopy (SIM) is used for various applications in cell biology, neuroscience, and other detection and diagnostic purpose is expected to accelerate the market growth.  

Analysis by Region

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North America accounted for a major share in the global super-resolution microscope market. The dominance of the market in the region is attributed to the increasing healthcare expenditure and increasing focus of the market players in the region on new product launches. Additionally, the growing number of pharmaceutical & biotechnological industries and academic institutes in the region is expected to propel the market growth.

Furthermore, Europe accounted for a considerable market share in 2021 owing to the increasing chronic disease prevalence and the rising focus on research & innovations is expected to boost the market growth.

• For instance, in November 2021, according to the NCBI article, Europe registered 4.0 million cases of cancer. Such growing cases of chronic diseases have been increasing the adoption of super-resolution microscopes for efficient disease diagnosis.

Moreover, Asia Pacific is expected to grow at a significant CAGR during the forecast period due to the increasing adoption of these microscopes in academic and research institutes and increasing healthcare expenditure which has been boosting the adoption of these advanced technologies for efficient diagnosis. 

Key Players Covered

The report will include key players such as Nikon, Leica Microsystems, Bruker, Hitachi High-Tech Corporation, Applied-Precision, GE Healthcare, Thermo Fisher Scientific, Sysmex Corporation, PicoQuant, and others.

Segmentation

Key Industry Development

The increasing research and development of chronic diseases like cancer and neurological disorders have been increasing the demand for super-resolution microscopes in the market.

• In October 2020, Bruker announced the launch of Vutara VXL super-resolution fluorescence microscope for nanoscale biomedical imaging.


• In March 2018, Nikon released the N-SIM Super-Resolution Microscope, which is used to detect super-imaging live cells.


• In December 2021, Hitachi High-Tech Corporation announced the launch of FE-SEM 1 models, the SU8600 and SU8700, an advanced super-resolution microscope. This product launch is expected to increase the company's share in the market.


• In September 2019, GE Healthcare announced the launch of DeltaVision OMX Flex super-resolution microscope to visualize live cell samples.