"Designing Growth Strategies is in our DNA"

Digital PCR Market Size, Share & COVID-19 Impact Analysis, By Type (Droplet Digital PCR, Chip-based Digital PCR, and Others), By Product (Instruments and Reagents & Consumables), By Indication (Infectious Diseases, Oncology, Genetic Disorders, and Others), By End-user (Hospital & Clinics, Pharmaceutical & Biotechnology Industries, Clinical Laboratories, and Academic & Research Organizations), and Regional Forecast, 2023-2030

Region : Global | Format: PDF | Report ID: FBI102014

 

KEY MARKET INSIGHTS

Play Audio Listen to Audio Version

The digital PCR market size was valued at USD 485.1 million in 2022 and is projected to grow from USD 584.5 million in 2023 to USD 2,379.9 million by 2030, exhibiting a CAGR of 22.2% during 2023-2030. North America dominated the global market with a share of 43.99% in 2022.


A digital polymerase chain reaction is a biotechnological advancement of conventional technology. It is a high-throughput absolute quantitative method that provides a sensitive and reproducible way of measuring the amount of DNA or RNA in a sample.


The rise in prevalence of infectious diseases, cancer, and genetic disorders, the introduction of products, increasing acquisitions, and the growing adoption of the technology by laboratories are some of the key factors expected to drive the market growth during the forecast period. Moreover, rising technological advancements in digital devices are projected to contribute to the market growth during the forecast period.


COVID-19 IMPACT


COVID-19 Pandemic Propelled the Market Growth due to Increase in SARS CoV-2 Testing


The impact of COVID-19 resulted in considerably high growth of the market in 2020. This is attributed to the vast spread of the virus, thereby increasing the demand for effective diagnostics to control its spread. The global market witnessed a humongous growth rate of 38.6% in 2020 as compared to 18.1% in 2019.


The reallocation of healthcare resources for COVID-19 treatment increased the number of people going for the COVID-19 diagnosis and the adoption of the device in clinical laboratories, and research institutes, thereby fueling the demand for the devices. Furthermore, the positive impact was due to the strong increase in COVID-19 testing in high-burden countries globally. Additionally, during the initial days of the pandemic, the resources were devoted to fight the coronavirus pandemic due to the strong infectious nature of the disease. The market players witnessed growth in the revenue generated during 2020.



  • For instance, Bio-Rad Laboratories, Inc., a key player in the market, registered a revenue of USD 2,545.6 million in 2020, an increase of 10.1% as compared to 2019. The growth is attributed to the increased adoption of devices in diagnostics centers for the diagnosis of COVID-19.


Decline in the number of COVID-19 cases among the population post pandemic limited the use of COVID-19 test kits and use of digital PCR devices across healthcare settings.



  • According to Qiagen N.V. annual report 2021, sales in digital PCR related segment fell by 10.0% to USD 390.8 million due to a very significant decline in COVID-19 testing demand in 2021.


However, the resumption of routine medical diagnosis at hospitals and diagnostic centers in 2021 augmented patient visits to healthcare settings. Moreover, rising emphasis of key players on production and launch of new dPCR assays & equipment for extensive biopharma applications further propelled the adoption of these devices. Thus, these factors further augmented the demand for these tests in 2021 at a considerable pace as compared to 2020.



  • In October 2021, Stilla launched Naica, a digital polymerase chain reaction system that features six fluorescent channels. The Naica system supports cell & gene therapy research, cancer and liquid biopsy studies, and the detection of infectious diseases in wastewater and food.


LATEST TRENDS


Request a Free sample to learn more about this report.


Shift of Healthcare Providers from Droplet to Chip-based Tests to Boost Market


The shift from droplet to chip-based tests for the diagnosis of various diseases has been pivotal in the advancement of the devices. In commercially available droplet digital test kits, the droplets have to be transferred manually, leading to underestimation of the targets. Moreover, ddPCR kits also pose a risk of cross-contamination during the transfer of the sample. On the other hand, in a chip-based technology, droplets always run in channels, reducing the risk of cross-contamination.


This innovation is expected to increase its adoption for the diagnosis of various diseases in the near future. Moreover, the increasing incidence of infectious diseases and the growing prevalence of cancer are expected to shift healthcare providers to chip-based devices. This is further projected to propel the digital PCR market growth during the forecast period.


DIGITAL PCR MARKET GROWTH FACTORS


Technological Advancements in dPCR to Enhance Market Growth


Digital polymerase chain reaction is the refinement of conventional technology that can be used to quantify and clonally amplify nucleic acids directly. Increasing research and development activities and growing demand for innovative devices have led to the introduction of various PCR technologies offering great benefits. The introduction of innovative devices based on techniques such as droplet, chip-based, beam, and crystal reaction, by key market players is anticipated to drive market growth.



  • In November, 2022, Shenzhen New Industries Biomedical Engineering Co., Ltd. launched a new product in the Snibe Molecular portfolio, the Molecision S6 digital PCR system, at MEDICA 2022. The Molecision S6 is an automated, integrated digital PCR system that provides a full-platform solution for research/in vitro diagnostics.


Such technological advancements are expected to fuel the market during the forecast timeframe (2023-2030).


Several Benefits of dPCR over Real-time Polymerase Chain Reaction to Boost Market Globally


Tests based on digital technique help to deliver a complete measure of target nucleic acid molecules than the relative measure achieved from real-time devices. This absolute DNA quantification allows for reproducibility, sensitivity, and precision, further enabling researchers to quantify smaller differences and precisely measure minor variants.


Additionally, despite the wide application of real-time devices chain reaction, it is not a preferred technique for detecting various parasitic infectious diseases such as malaria and COVID-19 due to multiple types of genomes present in the virus and extremely low template concentration available in the sample. Digital droplet devices overcome those issues and deliver accurate results with better comparability of results from different groups.



  • For instance, in March 2022, according to an article by Clinical Microbiology Review for the detection and diagnosis of SARS-CoV-2, tests based on digital technology have been extensively used over real-time polymerase chain reaction due to various benefits associated with it.


Various advantages associated with these digital devices over real-time devices are expected to increase the adoption of tests and instruments based on digital technology during the forecast period.


RESTRAINING FACTORS


High Cost of Instruments, and Presence of Other Alternatives such as NGS May Limit Market Growth


Despite various advantageous applications of digital polymerase chain reaction, a few limitations are associated with its use, which can hamper its adoption in the market.


Certain limitations, such as higher cost of these digital devices as compared to other options, may limit its adoption. This factor gives rise to multiple alternative options in the market. For instance, counting PCR is an alternative to the digital technique for absolute quantification. It quantifies viral load, copy number variation, and gene expressions. Such an alternative is expected to limit the growth of these digital devices in the market.



  • For instance, in August 2022, according to the Frontiers Media S.A. article, limitations of digital PCR, such as the high cost of instrument, and its limited versatility of reagents as compared to NGS, led to its limited adoption across general biochemistry laboratories.


Additionally, trained personnel can only handle these digital droplet devices to perform and quantify the results. Many equipment and reagents are not easily available for microfluidic technologies, limiting their adoption in many underdeveloped countries that are more vulnerable to viral infections.


Such limitations associated with the use of these digital devices coupled with the presence of other effective alternatives can restrain the overall market growth in the coming years.


SEGMENTATION


By Type Analysis


To know how our report can help streamline your business, Speak to Analyst


Droplet dPCR Segment to Hold a Major Share due to Increasing Product Launches for Infectious Disease Diagnosis


By type, the market is divided into droplet digital PCR, chip-based digital PCR, and others.


In 2022, the droplet dPCR segment held the highest market share. It is anticipated to expand at a substantial CAGR during the forecast period, 2023-2030. The growth is attributed to the increasing emphasis of market players on the development and commercialization of dPCR for infectious disease diagnostics.



  • In April 2023, Bio-Rad Laboratories, Inc., launched its new QX600 Droplet Digital PCR System. This device utilizes the same droplet generation and processing protocols as the QX200 system, and enables easy adoption of its advanced multiplexing capabilities.


Furthermore, the increasing prevalence of infectious diseases and the advantages of these devices in the diagnosis of diseases are expected to boost the segmental growth during the forecast period.



  • For instance, in June 2022, as per an article by NCBI, digital droplet PCR is more sensitive than reverse transcription quantitative real-time polymerase chain reaction and is usually considered the superior choice in detection of viral pathogens in clinical specimens.


The chip-based segment is projected to expand at a moderate CAGR during the forecast timeframe. The segmental growth is attributed to the sensitivity of chip-based tests in detecting strain’s specificity with less variability compared to the current standard of plate count enumeration techniques and quantitative polymerase chain reaction.


By Product Analysis


Instruments to Hold a Major Share due to Increasing Adoption of Digital Technologies


Based on product, the market is segmented into instruments, and reagents & consumables.


The instruments segment accounted for the largest global digital PCR market share in 2022 and is expected to expand at a substantial CAGR during the forecast period. The largest share of the segment is attributed to the increasing initiatives of the market players for the launch of new products and rising applications of this device in the market.



  • In August 2023, F. Hoffmann-La Roche AG launched a digital PCR system, to fight against cancer and other diseases. The Digital LightCycler System is a next-generation system that helps clinical researchers better predict cancer, genetic disease or infection.


The reagents & consumables segment is projected to expand at the highest CAGR during the forecast timeframe. The growth of the segment is due to increasing commercialization of these digital device kits for diagnosis purposes. Furthermore, due to the COVID-19 pandemic, governments provided emergency use authorization to certain kits based on digital techniques for the diagnosis of COVID-19, which is anticipated to further boost the market growth in the long run.



  • In May 2020, the FDA granted emergency use authorization (EUA) for Bio-Rad's SARS-CoV-2 ddPCR Kit in the U.S. The kit is a COVID-19 diagnostic tool with high sensitivity and precision beyond that of qPCR assays.


By Indication Analysis


Clinically Proven Effectiveness of Digital Polymerase Chain Reaction in Infectious Diseases to Increase Demand


Based on indication, the market is segmented into infectious diseases, oncology, genetic disorders, and others.


The genetic disorders segment dominated the market in 2022 and is expected to expand at a moderate CAGR during the forecast timeframe, 2023-2030. The growth of the segment is attributed to the increasing adoption of these devices to identify gene alterations due to its high sensitivity and specificity in detection.



  • According to an article published by National Library of Medicine in 2023, the sensitivity of the RT-qPCR rapid test was 37.9%, the specificity was 65.5% as compared to RT-PCR rapid tests.


The oncology segment is projected to expand at a substantial CAGR during the forecast timeframe. The growth of the segment is attributed to the increasing prevalence of cancer diseases and the growing adoption of these digital devices over other devices in cancer research.



  • According to an article published by America Cancer Society in 2022, around 1,918,030 new cancer cases were diagnosed in the U.S.


The infectious diseases segment is anticipated to expand at the highest CAGR during the forecast period. The clinically proven potential advantages of these droplet digital devices in the diagnosis of infectious diseases, including viral, bacterial, and parasitic infections are expected to boost the adoption of these devices, thereby propelling segmental growth. 


By End-user Analysis


Academic & Research Organizations to Continue Dominance due to Higher Adoption of Digital Technologies for Research Activities


Based on end-user, the market is segmented into hospitals & clinics, pharmaceutical & biotechnology industries, clinical laboratories, and academic & research organizations.


The academic & research organizations segment held the largest market share and is expected to expand at a moderate CAGR during the forecast period. The segment's growth is attributed to the increasing use of these devices in research studies in various fields, including oncology, genetic diseases, and others.



  • In February 2023, Thermo Fisher Scientific Inc., announced the launch of its new digital PCR research solution, the Applied Biosystems QuantStudio Absolute Q AutoRun dPCR suite.


The clinical laboratories segment is projected to expand at the highest CAGR during the forecast timeframe. The segment's growth is attributable to the increasing prevalence of infectious diseases and the rising use of these digital devices for the diagnosis of various types of these diseases. Furthermore, with the outbreak of COVID-19, many market players increased their focus on developing and commercializing COVID-19 diagnostics kits.



  • In March 2020, Bio-Rad Laboratories, Inc. and Biodesix, Inc., a diagnostics company in lung disease, announced their partnership to bring the COVID-19 droplet digital polymerase chain reaction test to the FDA for an Emergency Use Authorization (EUA) approval to support the escalating need for testing in the U.S. Such partnerships for new product approvals related to COVID-19 contributed to the segmental growth in 2020.


REGIONAL INSIGHTS


North America Digital PCR Market Size, 2022 (USD Million)

To get more information on the regional analysis of this market, Request a Free sample


The North America market was valued at USD 213.4 million in 2022 and is projected to expand at a substantial CAGR during the forecast period. The growth is due to the highly alert and economically stable population. Moreover, the increasing adoption of technologically advanced and high-cost diagnostics in the region is also expected to propel the regional market growth during the forecast period.



  • According to research statistics published by SDi report in December 2022, the adoption of dPCR among the 248 scientists surveyed in the U.S. labs was over 40%.


Europe is anticipated to expand at a moderate CAGR during the forecast timeframe. The growth is attributable to strong infectious diagnostics volume in key European countries and the rising expenditure on research & development in Europe.



  • In March 2022, Stilla Technologies, announced a new project with investment of USD 31.3 million by the European Investment Bank. The project focuses on accelerating the development of next-generation genetic tests by providing a ground-breaking and flexible solution.


The market in Asia Pacific is expected to grow at the highest CAGR during the forecast period. The market growth across the region is attributed to the improvement in healthcare infrastructure in Asian countries, the high burden of chronic and infectious diseases in the region, and increasing consciousness of individuals in terms of better treatment outcomes.



  • For instance, according to the data provided by the National AIDS Control Organization in April 2022, in response to an RTI query, over 17 lakh people contracted HIV in India in the last 10 years. Such increasing prevalence of infectious diseases has been increasing the demand for effective diagnosis in the region, thereby spurring the market growth in Asia Pacific.


The market in Latin America and the Middle East & Africa is expected to expand at a significant CAGR during the forecast period. The growth is attributable to the growing number of clinical studies to evaluate the efficacy of these devices and the increasing commercialization of such products in the region. Furthermore, increasing efforts to enhance the healthcare infrastructure of these countries are expected to further support market growth across the region.


KEY INDUSTRY PLAYERS


Diverse Portfolio of Leading Players and Strong Focus on Partnerships and Acquisitions to Strengthen their Market Position


The market is consolidated due to large market shares of key companies operating in the market.


The key companies operating in the market are Bio-Rad Laboratories, Inc., Thermo Fisher Scientific Inc., and Qiagen. In 2022, these three companies together accounted for a major share of the market.


Bio-Rad Laboratories, Inc. dominated the market with the highest market share. The company’s market dominance is due to its strong droplet digital test product portfolio covering instruments and consumables. Moreover, the company’s strong market share is due to the acquisitions of other digital devices manufacturers in the historical years. Moreover, other major players, such as Qiagen N.V., are now focusing on inorganic strategies such as collaborations with new dPCR manufacturers for production and expansion of existing product portfolio globally. These factors are further propelling the company growth in the market.



  • In August 2022, Bio-Rad Laboratories, Inc. announced the acquisition of Curiosity Diagnostics, Sp. Z. O. o., a Poland-based developer of innovative technology solutions for the medical diagnostic and healthcare markets.

  • In July 2022, Qiagen announced a series of enhancements through collaborations for its QIAcuity series of digital PCR instruments designed to drive greater use among customers, particularly those involved in the biopharma industry.


Other prominent players in the global market include Stilla, Sysmex Corporation, JN Medsys, and Standard BioTools Inc. (Fluidigm Corporation). These companies are focusing on strategic initiatives to gain more market shares during the forecast period.



  • In March 2023, Stilla and AtilaBiosystems entered into an agreement to market co-labelled digital PCR kits.


LIST OF KEY COMPANIES PROFILED IN DIGITAL PCR MARKET:



KEY INDUSTRY DEVELOPMENTS:



  • In October 2022, Standard BioTools Inc. announced the launch of the X9 Real-Time PCR System, an innovative high-capacity genomics instrument offering superior efficiency.

  • In April 2022, Stilla and Promega Corporation announced their co-marketing agreement that combined sample preparation with the latest Maxwell systems and digital polymerase chain reaction on the six-color Naica system. This collaboration strengthened both companies’ digital workflow solutions.

  • In March 2022, Stilla announced its partnership with 12 distributors across the EMEA region. With this partnership, the company expanded its presence in the EMEA region.

  • In September 2021, Thermo Fisher Scientific Inc., announced the launch of Applied Biosystems QuantStudio Absolute Q DPCR System.

  • In August 2021, QIAGEN and GT Molecular announced the collaboration to offer a complete SARS-CoV-2 wastewater detection solution based on QIAcuity Digital PCR technology.


REPORT COVERAGE


An Infographic Representation of Digital PCR Market

To get information on various segments, share your queries with us



The research report provides a detailed competitive landscape and market dynamics. It focuses on key aspects such as the prevalence of chronic disease, regulatory scenarios by key countries/regions, and an overview of microfluidic consumables in the market. Furthermore, the report provides information on key industry developments, pricing analysis of consumables by key companies, and detailed product mapping of consumables supplied by key companies. In addition, the report includes insights related to technological advancements in the devices and the impact of COVID-19 on the market.


Report Scope & Segmentation


























































  ATTRIBUTE 



 DETAILS



Study Period



2019-2030



Base Year



2022



Estimated Year



2023



Forecast Period



2023-2030



Historical Period



2019-2021



Growth Rate  



CAGR of 22.2% from 2023-2030



Unit



Value (USD million)



By Type


 




  • Droplet Digital PCR

  • Chip-based Digital PCR

  • Others



By Product


 




  • Instruments

  • Reagents & Consumables



By Indication


 




  • Infectious Diseases

  • Oncology

  • Genetic Disorders

  • Others



By End-user


 




  • Hospitals & Clinics

  • Pharmaceutical & Biotechnology Industries

  • Clinical Laboratories



  • Academic & Research Organizations



By Geography


 




  • North America (By Type, Product, By Indication, End-user, and Country)

    • U.S.

    • Canada



  • Europe (By Type, Product, By Indication, End-user, and Country/ Sub-region)

    • U.K.

    • Germany

    • France

    • Italy

    • Spain

    • Rest of Europe



  • Asia Pacific (By Type, Product, By Indication, End-user, and Country/Sub-region)

    • China

    • Japan

    • India

    • Australia

    • Southeast Asia

    • Rest of Asia Pacific



  • Latin America (By Type, Product, By Indication, End-user, and Country/ Sub-region)

    • Brazil

    • Mexico

    • Rest of Latin America



  • Middle East & Africa (By Type, Product, By Indication, End-user, and Country/ Sub-region)

    • GCC

    • South Africa

    • Rest of Middle East & Africa





Frequently Asked Questions

Fortune Business Insights says that the global market stood at USD 485.1 million in 2022 and is projected to reach USD 2,379.9 million by the end of 2030.

The market is expected to expand at a CAGR of 22.2% during the forecast timeframe (2023-2030).

The droplet digital polymerase chain reaction segment is the leading segment in the market by type.

The growing adoption of digital techniques over other conventional methods and the rising incidence of chronic and infectious diseases are some of the factors driving the market.

Bio-Rad Laboratories, Inc., Thermo Fisher Scientific Inc., and Qiagen are the top players in the market.

Seeking Comprehensive Intelligence on Different Markets?
Get in Touch with Our Experts

Speak to an Expert
  • Jul, 2023
  • 2022
  • 2019-2021
  • 130

    CHOOSE LICENSE TYPE

  • $4850
    $5850
    $6850

Personalize this Research

  • Granular Research on Specified Regions or Segments
  • Companies Profiled based on User Requirement
  • Broader Insights Pertaining to a Specific Segment or Region
  • Breaking Down Competitive Landscape as per Your Requirement
  • Other Specific Requirement on Customization
Request Customization Banner

Client Testimonials

“This report is really well done and we really appreciate it! Again, I may have questions as we dig in deeper. Thanks again for some really good work.”

- U.S.-based biotechnology company focussing on treatment of chronic pain.

“Kudos to your team. Thank you very much for your support and agility to answer our questions.”

- Europe-based provider of solutions to automate data centre operations.

“We appreciate you and your team taking out time to share the report and data file with us, and we are grateful for the flexibility provided to modify the document as per request. This does help us in our business decision making. We would be pleased to work with you again, and hope to continue our business relationship long into the future.”

- India-based manufacturer of industrial and specialty intermediates with a strong global presence.

“I want to first congratulate you on the great work done on the Medical Platforms project. Thank you so much for all your efforts.”

- One of the largest cosmetics company in the world.

“Thank you very much. I really appreciate the work your team has done. I feel very comfortable recommending your services to some of the other startups that I’m working with, and will likely establish a good long partnership with you.”

- U.S. based startup operating in the cultivated meat market.

“We received the below report on the U.S. market from you. We were very satisfied with the report.”

- Global hearing aids manufacturer.

“I just finished my first pass-through of the report. Great work! Thank you!”

- U.S. based solar racking solutions provider.

“Thanks again for the great work on our last partnership. We are ramping up a new project to understand the imaging and imaging service and distribution market in the U.S.”

- World’s leading advisory firm.

“We feel positive about the results. Based on the presented results, we will do strategic review of this new information and might commission a detailed study on some of the modules included in the report after end of the year. Overall we are very satisfied and please pass on the praise to the team. Thank you for the co-operation!”

- Germany based machine construction company.

“Thank you very much for the very good report. I have another requirement on cutting tools, paper crafts and decorative items.”

- Japanese manufacturing company of stationery products.

“We are happy with the professionalism of your in-house research team as well as the quality of your research reports. Looking forward to work together on similar projects”

- One of the Leading Food Companies in Germany

“We appreciate the teamwork and efficiency for such an exhaustive and comprehensive report. The data offered to us was exactly what we were looking for. Thank you!”

- Intuitive Surgical

“I recommend Fortune Business Insights for their honesty and flexibility. Not only that they were very responsive and dealt with all my questions very quickly but they also responded honestly and flexibly to the detailed requests from us in preparing the research report. We value them as a research company worthy of building long-term relationships.”

- Major Food Company in Japan

“Well done Fortune Business Insights! The report covered all the points and was very detailed. Looking forward to work together in the future”

- Ziering Medical

“It has been a delightful experience working with you guys. Thank you Fortune Business Insights for your efforts and prompt response”

- Major Manufacturer of Precision Machine Parts in India

“I had a great experience working with Fortune Business Insights. The report was very accurate and as per my requirements. Very satisfied with the overall report as it has helped me to build strategies for my business”

- Hewlett-Packard

“This is regarding the recent report I bought from Fortune Business insights. Remarkable job and great efforts by your research team. I would also like to thank the back end team for offering a continuous support and stitching together a report that is so comprehensive and exhaustive”

- Global Management Consulting Firm

“Please pass on our sincere thanks to the whole team at Fortune Business Insights. This is a very good piece of work and will be very helpful to us going forward. We know where we will be getting business intelligence from in the future.”

- UK-based Start-up in the Medical Devices Sector

“Thank you for sending the market report and data. It looks quite comprehensive and the data is exactly what I was looking for. I appreciate the timeliness and responsiveness of you and your team.”

- One of the Largest Companies in the Defence Industry
We use cookies to enhance your experience. By continuing to visit this site you agree to our use of cookies . Privacy.
X