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The global ophthalmic disease therapeutics market size was USD 33.56 billion in 2022. The market is projected to grow from USD 35.57 billion in 2023 to USD 54.87 billion by 2030, exhibiting a CAGR of 6.4% during the forecast period.
Ophthalmic disease therapeutics include drugs and therapies for the treatment of several ocular conditions such as glaucoma, dry eye disease, retinal diseases, and others. The increasing prevalence of these conditions among the population along with rising healthcare burden caused due to these conditions is expected to boost the demand for novel therapies and approaches for the management of these diseases.
Along with this, increasing research & development activities among market players to develop novel therapies and effective drugs for the ophthalmic disease therapeutics is expected to spur the ophthalmic disease therapeutics market growth.
However, the lack of awareness regarding the conditions along with limited availability of effective drugs and novel therapies for the treatment of ophthalmic disease is expected to restrain the growth of the market.
Reduced Number of Patient Visits During Pandemic Resulted into a Slower Growth of the Market
The COVID-19 impact on the market growth was negative during the forecast period. The temporary shutdown of the orthopedic clinics, higher focus of healthcare providers toward COVID-19 patients is one of the major factors responsible for the slower growth of the market during the pandemic.
The lockdown restrictions imposed by the government authorities across the regions resulted in cancellation or postponement of services associated with several ophthalmic conditions and resulted in reduced number of patient visits to the hospitals and clinics. This led to decreased demand for ophthalmic disease therapeutics among the patient population globally.
The major players operating in the market witnessed a decline in their revenues owing to the demand gap due to the COVID-19 pandemic. However, the decline in the revenues was solely not associated with the pandemic but several factors including loss of patents for branded drugs, increasing generic competition, and divestiture of the business by several companies led to decline of the revenue.
However, with the uplifting of lockdown restrictions, the number of ophthalmic clinic visits significantly increased in 2021 recovering the missed and canceled appointments for various indications. This resulted in a slow recovery of the market in 2021 globally.
Also, a few players witnessed growth in their revenue in 2021 owing to recovery of the market from the COVID-19 pandemic and increased demand for ophthalmic disease therapeutics products.
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Rising Technological Advancements in Drug Delivery Options
The focus of research & development activities by various healthcare agencies and market players is shifting toward the development of innovative drug delivery systems. The challenges of the current ocular drug delivery systems owing to the anatomy and physiology of the eye is one of the major factors contributing to the shifting focus of the market players.
Also, research institutes are increasing their focus to develop and introduce novel approaches for drug delivery and this is leading to increasing clinical studies. According to a 2021 report published by the Department of Ophthalmology of Penn Medicine, the researchers discovered that the use of an engineered, artificial protein coating can improve the ophthalmological drug uptake.
Similarly, the increasing focus on novel therapies and expansion of product portfolio are some of the major factors contributing to the shifting preference of the patient population.
Also, the rising partnerships and collaborations among market players and research organizations to develop innovative and more effective gene therapies for the conditions is expected to support the shifting preference of the patient population toward novel therapies.
Rising Prevalence of Ophthalmic Conditions to Surge the Demand for Innovative Drugs
The growing prevalence of ophthalmic conditions such as glaucoma, retinal diseases, dry eye disease, and others among the population is one of the major factors contributing to the rising patient population globally. The prevalence of these ophthalmic conditions is found to be higher in the geriatric population.
The rising awareness among the general population regarding the ocular conditions owing to increasing number of initiatives carried out by various healthcare agencies, government bodies, and market players is resulting in higher diagnosis and treatment rate among the population.
Along with these factors, the rising healthcare expenditure and increasing number of ophthalmologists in the developed and emerging countries are some other factors that are expected to augment the demand for ophthalmic disease therapeutics in the market.
Thus, these factors coupled with increasing focus of the market players to develop and introduce novel drugs, and therapies for the treatment of the conditions is expected to boost the demand and adoption of these drugs in the market during the forecast period.
Increasing Clinical Trials and Pipeline Candidates for Innovative Drugs and Therapies to Propel the Market Demand
The rising prevalence of ophthalmic disease among the population is one of the factors contributing to the growing demand for effective drugs and treatment for the condition. This is resulting in increasing focus of market players and research organizations to develop and launch innovative therapies for the treatment of the condition.
The rising efforts of the market players in the R&D activities to develop novel therapies for the treatment of the condition is expected to exhibit a higher demand for ophthalmic disease therapeutics in the market during the forecast period. The increasing focus and robust efforts of the key players operating in the market to develop and launch novel therapies for catering the unmet demand for the rising patient population is expected to increase the consumption of the ophthalmic drugs.
Thus, increasing patient population undergoing treatment along with rising number of approvals and launches of innovative drugs and therapies are expected to spur the market growth during the forecast period.
High Cost of Biologics and Overall Treatment Cost is Limiting the Adoption of the Product
There are several clinical benefits of biologics and biosimilars such as higher effectiveness, safety, and others. However, certain limitations such as higher cost of biologics, higher out-of-pocket spending, and others. Higher cost of biologics owing to its several benefits and various costs associated with its development and approvals is a crucial factor limiting the adoption of these drugs in the emerging countries.
Other challenges for the healthcare system especially in the emerging countries such as China, Brazil, Mexico, and African countries is lower awareness of the conditions among the population resulting in lower rate of diagnosis of the conditions. Therefore, the increasing gap between the patient population and treatment for the conditions along with higher out-of-pocket expenditure is expected to slow the adoption of ophthalmic disease therapeutics.
The lack of awareness regarding various ophthalmic conditions among the general population in the emerging countries such as Mexico, Saudi Arabia, and other African countries, lack of reimbursement policies in these countries are some of the other factors anticipated to restrain the market growth in these countries during the forecast period.
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Anti-VEGF is Expected to Grow in the Market Owing to Rising R&D Activities by Market Players
On the basis of drug class, the market is segmented into anti-inflammatory, anti-infectives, anti-VEGF, anti-glaucoma, and others. The anti-glaucoma is further sub-segmented into beta blockers, prostaglandins analogs, alpha adrenergic agonists, carbonic anhydrase inhibitors, combination drugs, and others.
Anti-inflammatory segment held the largest share in 2022 owing to factors such as increasing patient pool undergoing treatment of ocular allergies and inflammation.
Anti-VEGF segment is expected to register at a significant CAGR during the forecast period. The increasing prevalence of retinal disorders such as diabetic retinopathy, age-related macular degeneration, and others along with rising diagnosis rate of these conditions among the population is resulting in growing demand for anti-VEGF therapy in the regions.
Also, the rising number of approvals and launches of the products is contributing to the growth of the segment globally.
On the other hand, the rising prevalence of glaucoma along with increasing R&D focus of the market players, collaborations among these players to develop, and introduce anti-glaucoma therapies to cater the rising demand for these among the patient population is expected to fuel the segmental growth in the market.
The growing diagnosis rate of ocular infections and retinal diseases among the population is an important factor responsible for the rising demand for these drugs.
Semisolid Segment is Projected to Dominate Owing to Increasing Clinical Benefits of the Products
On the basis of dosage form, the market is segmented into liquid, solid, and semisolid. Semisolid segment is expected to grow at a higher CAGR owing to the rising number of approvals and launches of products such as ointment, suspensions, gels, and others. Rising applications of ointment including inflammatory conditions, infections, and dry eye due its increased effectiveness is leading to rising adoption of the semisolid products. Along with this, increasing focus of the key players to gain approvals and introduce more products is another factor contributing to the growth of the segment.
Liquid segment dominated the market in 2022 owing to its increasing adoption among the patient population due to several benefits such as easy to use, increased time period of contact between the product and the substance, increased solubility, and others. The rising prevalence of ophthalmic conditions and increasing patient population undergoing treatment with eye drops, eye solutions, and others is expected to spur the segmental growth.
On the other hand, solid segment is expected to grow in the market owing to the rising focus of the market players to develop innovative products including the oral drugs or various ophthalmic conditions.
Thus, the increasing patient population along with rising diagnosis rate and demand for therapies is leading to rising focus of the players to launch drugs with different routes of administration.
On the basis of disease indication, the market is segmented into glaucoma, dry eye disease, retinal diseases, allergy & infections, and others.
Retinal diseases dominated the market in 2022. The rising prevalence of retinal diseases such as diabetic macular edema, macular degeneration and diabetic retinopathy, and others among the population is one of the major factors responsible for the growing patient population. This combined with the increasing number of initiatives for rising awareness about these conditions among the population is resulting in growing diagnosis rate of the conditions and higher demand for therapeutic products.
Dry eye disease segment is expected to grow at a higher CAGR during the forecast period owing to the increasing focus of the key players to develop and introduce drugs for the treatment of the condition.
Glaucoma segment is expected to grow due to the rising prevalence of the condition especially in the geriatric population. The rising patient pool suffering from angle-closure glaucoma globally is one of the major factors anticipated to boost the demand for therapies among the patient population.
On the other hand, the adoption of treatment for glaucoma, eye allergies & infections, and others is rising among the patient population. This along with increasing prevalence of these conditions is leading to rising focus of the market players to develop and introduce novel and effective therapies for the treatment.
On the basis of distribution channel, the market is segmented into hospital pharmacies and retail & online pharmacies.
The retail & online pharmacies segment dominated the market in 2022 and is expected to register a higher CAGR during the forecast period. The rising number of patient visits to the ophthalmology clinics for the treatment of various ophthalmic is one of the major reasons contributing to the growth of the segment. The increasing number of digital users and increasing preference of the patients to procure medications online in both developed and emerging countries is an important factor contributing to the growth of the segment.
On the other hand, hospital pharmacies segment is expected to grow owing to increasing inpatient admissions for hospitals. This is leading to a rising number of procurement of the drugs from the hospital pharmacies which is anticipated to propel the segmental growth.
North America Ophthalmic Disease Therapeutics Market Size, 2022 (USD billion)
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On the basis of region, North America accounted for the highest share and generated a revenue of USD 13.79 billion in 2021. The region is anticipated to dominate the market in the upcoming years owing to growing prevalence of various ophthalmic disorders along with higher diagnosis and treatment rate. Moreover, growing healthcare expenditure supporting eye care and eye health in the region, presence of adequate reimbursement for various ophthalmic disorders promotes the adoption of advanced, and novel treatment in the key countries in the region.
Additionally, a conducive environment provided for the research and development of various innovative drugs to cure ophthalmic diseases along with growing approval of new drugs are some other factors contributing to the growth of the market.
On the other hand, Europe accounted for the substantial share in the market. Rising launch of biologics and biosimilar intended for the treatment of various eye diseases, rising emphasis on the proper management of ophthalmic conditions, and growing efforts by the key players operating in the market to expand their geographical footprint. The launch of new products, among others are a few factors primarily contributing to the market growth.
Market in Asia Pacific is expected to grow at a comparatively higher CAGR during the forecast period owing to rising prevalence of geriatric population prone to develop various ophthalmic conditions. Growing strategic initiatives by the companies present in the region to increase the penetration of various drugs in the regional market, rising awareness among the patient population regarding new and recent treatments, and others are some factors supporting the market growth.
Further, Latin America is expected to grow during the forecast period. The rising prevalence of various eye related disorders, the increasing awareness regarding the diseases among the general population, and rising efforts of the key players to introduce new drugs in the region are some of the major factors responsible for the growth of the market in the region.
Similarly, improving healthcare infrastructure and growing collaboration and partnerships among the key companies to improve the access of various ophthalmic drugs are a few factors augmenting the market growth of ophthalmic disease therapeutics in Latina America and the Middle East & Africa region.
Thus, all these factors are expected to augment the growth of the market in these regions.
Regeneron Pharmaceuticals Inc. to Lead the Market with Strong Product Portfolio
This is a consolidated market comprising a few players with a range of products, including prescription products as well OTC products. The increasing sales of the drug EYLEA in the U.S. and other markets is one of the major reasons contributing to the growing ophthalmic disease therapeutics market share of Regeneron Pharmaceuticals Inc. Also, the rising R&D expenditure of the market player for the ophthalmic product is another factor contributing to the higher market share of the company.
Santen Pharmaceutical Co. Ltd., is increasing its focus on the approval and introduction of the products globally with strategic mergers and acquisitions. This along with strong emphasis on R&D to develop and launch novel therapies for various ophthalmic conditions to cater to the rising demand from the population is expected to contribute to the company’s market hold.
The growing investment of other players in research and development activities for the development of novel drugs and therapies for the condition is resulting into increasing number of pipeline candidates for the treatment of ophthalmic disease. These factors are expected to increase the market share of these companies in the future.
An Infographic Representation of Ophthalmic Disease Therapeutics Market
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The research report covers a detailed analysis and overview. It focuses on key aspects such as competitive landscape, drug class, dosage form, disease indication, distribution channel, and region. Besides this, it offers insights into the market drivers, market trends, market dynamics, COVID-19 impact on the market, and other key insights. In addition to the factors mentioned above, the report encompasses several factors that have contributed to the growth of the market in recent years.
CAGR of 6.4% from 2023-2030
Value (USD billion)
By Drug Class, Dosage Form, Disease Indication, Distribution Channel, and Region
By Drug Class
By Dosage Form
By Disease Indication
By Distribution Channel
Fortune Business Insights says that the global market stood at USD 33.56 billion in 2022 and is projected to reach USD 54.87 billion by 2030.
In 2022, the market value stood at USD 33.56 billion.
The market will exhibit steady growth at a CAGR of 6.4% during the forecast period (2023-2030).
Currently, anti-inflammatory segment is leading by drug class. Anti-VEGF segment will lead the market during the forecast period.
Rising prevalence of ophthalmic disease, increasing diagnosis of the condition, increasing research and development activities by the major market players, and rising number of approvals and launches of ophthalmic disease therapeutics products are the key drivers of the market.
Regeneron Pharmaceutical Inc., AbbVie Inc., Santen Pharmaceutical Co. Ltd., and Novartis AG are the major players in the market.
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