"Designing Growth Strategies is in our DNA"

Normal Saline for Parenteral Use Market Size, Share & COVID-19 Impact Analysis, By Type (Plastic Bottles and Glass Bottles), By Application (Intramuscular Injection and Intravenous Injection), and Regional Forecast, 2023-2030

Region : Global | Format: PDF | Report ID: FBI104520

 

KEY MARKET INSIGHTS

Play Audio Listen to Audio Version

The normal saline for parenteral use market size was valued at USD 3.44 billion in 2023 and is projected to grow USD 5.48 billion by 2030, exhibiting a CAGR of 6.9% during 2023-2030. The rising prevalence of diarrhea, especially in children, drives the market growth.


Normal saline is used extensively in hospitals for a wide range of conditions such as dehydration, electrolyte imbalance, wound dressing, sepsis, hemorrhage, and others. According to the Victorian Agency for Health Information, neonatal sepsis occurs in 1 to 8 per 1,000 live births in Victoria, Australia. Globally, the condition is diagnosed in around 1 to 50 per 1,000 live births annually. This rising incidence of sepsis among neonates is poised to surge the demand for the solution.


The increasing government guidelines and recommendations for the use of 0.9% sodium chloride and fluid resuscitations in critical conditions are further poised to provide a considerable boost to the market growth. Surviving Sepsis Campaign (SSC), a joint collaboration of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM), recommends the use of crystalloid fluids for resuscitation during septic shock, which is adopted by many hospitals and academic associations. Moreover, 0.9% NaCl is one of the most commonly used crystalloid fluids, which is propelling the global normal saline for parenteral use market growth.


COVID-19 IMPACT


Decrease in Demand for IV Fluids amid COVID-19 Hampered the Market Growth


The COVID-19 pandemic had a profound impact on the healthcare sector. It increased the burden on healthcare professionals and hospitals. In order to dedicate all the healthcare resources to the management of COVID-19 patients, governments across the globe decided to postpone or cancel elective and non-urgent surgeries.



  • According to CovidSurg, over 28.0 million elective surgeries were estimated to have been canceled globally due to the COVID-19 pandemic during the 12-week period of peak disruption. Moreover, the NHS directives led to around 2.1 million operations being postponed in England.


The sharp decline in the number of surgeries has negatively impacted the demand for IV fluids, including normal saline.



  • ICU Med’s IV Solutions product line witnessed a decrxease of 10.3% in its revenue in the first six months of 2020 when compared to the same period in 2019.       

  • Similarly, the medication delivery segment of Baxter reported a decline of 1.6% during the first half of 2020.


The pandemic also decreased patient volumes in specialty clinics and care centers, resulting in fewer hospital admissions. These factors negatively impacted the market growth.


LATEST TRENDS


Increased Demand for Saline Due to the Flu Season to Boost the Market Growth


There is an increased demand for intravenous saline products, which are used to hydrate and deliver medications to patients hospitalized during the flu season. Flu seasons that have H3N2 as the more predominant strain of the Influenza A virus as compared to H1N1 lead to more severe complications and result in a considerable increase in flu-related hospitalizations.                                                                                                              


As per European Centres for Disease Prevention and Control (ECDC) estimates in 2022, the worst season of influenza is estimated to cause up to 50 million infections and leads to around 70,000 deaths in the European Union each year. During 2018-2019, 35.52 million influenza infection cases were reported in the U.S., resulting in a total of 490,561 hospital admissions. Prolonged flu season, particularly in the U.S., is expected to increase the demand for normal saline for parenteral use to multiple folds.


Request a Free sample to learn more about this report.


DRIVING FACTORS


Increasing Usage of Normal Saline for Dehydration and Sepsis to Propel the Market Growth


IV fluids are one of the most common medical interventions used globally. Saline has become the IV fluid of choice in hospital settings for the management of various conditions such as dehydration, vomiting, diarrhea, and management of fluid resuscitation in various critical conditions. Moreover, 0.9% NaCl is by far the most commonly used IV fluids.  Furthermore, among neonates, administration of 0.9% sodium chloride is the first step in the management of sepsis, hyponatremia, hypernatremia, and fluid deficits or imbalances due to certain medical conditions.


According to the National Center for Biotechnology Information, in the U.S., around 200 million liters of saline are sold annually. In addition, over 1 million liters of 0.9% sodium chloride are administered to patients across the globe daily. This increasing uptake of saline across various medical specialties in hospitals and clinics is a major factor bolstering the market growth.                                            


Rising Number of Hospital Admissions and Surgical Procedures to Foster Market Growth


The increasing number of hospital admissions in ICUs and NICUs has resulted in an increased demand for normal saline for parenteral use. Moreover, the majority of in-patients are administered with saline solutions during their stay in hospitals. According to the NHS, there are more than 5.0 million acute hospital admissions annually, and it is expected that the majority of the patients are exposed to intravenous fluid therapy.


According to the Admissions and Transitions Optimization Program, more than half a million hospital admissions annually in the U.S. are for dehydration. Thus, growing hospital admissions coupled with the increase in the number of surgeries are anticipated to fuel the market growth.


RESTRAINING FACTORS


Studies Suggesting Replacement of Saline with Balanced Fluids May Hinder the Market Growth 


Various studies have shown that using balanced IV fluids instead of saline reduces the risk of death and kidney damage significantly among hospitalized patients. For instance, in February 2019, one such study estimated that switching from saline to balanced IV fluids can result in around 60,000 fewer deaths and 100,000 fewer cases of kidney failure in the U.S. Another study conducted by Vanderbilt University concluded that for every 100 hospitalized patients that were given balanced fluids instead of saline, there was one fewer death or severe kidney problem, which is a huge impact in the context of over 35.0 million hospitalizations that happen in the U.S. annually.


The usage of balanced fluids in healthcare facilities has also increased due to the growing awareness about the harm saline can do to a patient’s kidneys.



  • According to an article published by Cureus in April 2021, Shaw et al. stated results in a retrospective observational study of approximately 30,000 patients undergoing major abdominal surgery. The in-hospital mortality was 5.6% in the group who received isotonic saline with common complications, including acute kidney injury, postoperative infections, and acidosis.


Thus, the gradual shift towards balanced fluids is anticipated to hamper the market growth.


SEGMENTATION


By Type Analysis


Growing Preference for Plastic Bottles for Breakage Prevention to Impel the Segment Growth


With respect to type, the market is categorized into glass bottles and plastic bottles.


The plastic bottles segment is anticipated to dominate the market during the forecast period. The rising preference for plastic bottles over glass to prevent breakage during supply and increasing strategic collaborations for IV fluids are the primary reasons for the growth of this segment. For instance, in March 2018, Grifols S.A. announced a distribution agreement with Henry Schein Inc. As per the terms of the agreement, Henry Schein marketed and distributed Grifols normal saline bag in the U.S. The product is currently manufactured in Grifols manufacturing unit in Spain, having a production capacity of 50.0 million units per year.


The glass bottles segment is expected to grow at a considerable CAGR during 2023-2030. The growth is attributed to high potential advantages of glass bottles such as low solution contamination, environmental benefits, among others over plastic bottles. This, coupled with the rising incidence of dehydration and the increasing number of NICUs, is projected to propel the growth of the glass bottles segment.


To know how our report can help streamline your business, Speak to Analyst

                                                                                           


By Application Analysis


Intravenous Segment Dominated Owing to Growing Prevalence of Vomiting


On the basis of application, the market is divided into intramuscular injection and intravenous injection. The intravenous segment accounted for the major portion of the market share in 2022. Intravenous injection is the most preferred route of administration for normal saline, which is the primary reason for the dominant share of the segment. Apart from this, the rising incidence of vomiting, diarrhea, and food poisoning is expected to proliferate the intravenous segment growth.


The intramuscular injection segment is expected to grow at a substantial CAGR owing to high advantages as compared to intravenous injections such as ease of administration, low invasiveness, among others.


REGIONAL INSIGHTS


North America Normal Saline for Parenteral Use Market Size, 2022 (USD Billion)

To get more information on the regional analysis of this market, Request a Free sample


The North American market stood at USD 1.26 billion in 2022. Factors attributed to the dominant share of the region are the strategic presence of key players and the rising uptake of 0.9% NaCl. According to the FDA database, even after two years of Hurricane Maria, hospitals in the U.S. faced a shortage of saline solutions. The dearth of normal saline created an opportunity for manufacturers to invest in expanding their production capacities. This factor is expected to boost the market growth in North America.


The Asia Pacific market is anticipated to hold a second prominent position during the forecast period. The market in Asia Pacific is anticipated to grow primarily due to the rising number of hospital admissions, growing geriatric population, and an expanding patient population. According to the Asia Pacific Sepsis Alliance, the estimated national sepsis incidence in the region ranges from 120 up to 1,600 per 100,000, which is poised to propel the regional growth.


European market growth is driven by active support from governments through the recommendations from the National Institute of Health and Care Excellence (NICE) and the European Society of Intensive Care Medicine (ESICM) on 0.9% sodium chloride administration.


The markets in Latin America and the Middle East & Africa are projected to grow owing to the improving healthcare infrastructure, the high prevalence of dehydration in Sub-Saharan Africa, and a significant increase in the number of hospitals.


KEY INDUSTRY PLAYERS


Baxter Held a Leading Position Owing to the Strong Distribution Network


In terms of revenue, Baxter held a dominating position in the market in 2022. The company is a leader in IV fluids and has an established distribution network and customer base. This is one of the key factors for the prominent position of the company in the market. On the other hand, a firm hold in China and high manufacturing capacity are factors responsible for the second leading position of the Kelun Group.


Moreover, manufacturers such as ICU Medical, Fresenius Kabi AG, SSY Group Limited, and others are focusing on R&D and strategic collaborations to strengthen their market position. This is expected to intensify market competition and boost their global normal saline for parenteral use market share during the forecast period.     


LIST OF KEY COMPANIES PROFILED:



  • Baxter (U.S.)

  • Kelun Group (China)

  • B. Braun Melsungen AG (Germany)

  • Fresenius Kabi AG (Germany)

  • SSY Group Limited (China)

  • ICU Medical (U.S.)

  • Double-Crane Pharmaceutical Co., Ltd. (China)

  • Otsuka Pharmaceutical Co., Ltd. (Japan)

  • Cisen Pharmaceutical Co., Ltd. (China)

  • Pharmally International Holding Co., Ltd. (China)


KEY INDUSTRY DEVELOPMENTS:



  • August 2022 - Assure Infusions, Inc., announced the construction of a manufacturing plant in Bartow, Florida. The center is fully automated with advanced robotics to make IV fluids that are in high demand in the U.S. healthcare system.

  • February 2022 - B. Braun SE, a German infusion therapy company received the FDA’s approval to begin operations at its new I.V. saline solution manufacturing facility in Daytona Beach, Florida.

  • October 2020 - The Laugfs Holdings Limited announced its planning to commence operations of its intravenous (IV) solution (saline) manufacturing plant located in the Koggala Export Processing Zone (EPZ) in Sri Lanka.

  • February 2020 - Eurolife Healthcare Pvt. Ltd., announced the acquisition of intravenous infusion business of TEVA Pharmaceutical Industries Ltd., in Hungary, for the development and commercialization of intravenous infusions plant in the U.S. and European markets.

  • July 2019 - Eurolife Healthcare Pvt Ltd, a specialty pharmaceuticals company, acquired Isreal-based Teva's intravenous infusion (IV) unit in Hungary for the expansion of its operations in the Europe and U.S. market.


REPORT COVERAGE


An Infographic Representation of Normal Saline for Parenteral Use Market

To get information on various segments, share your queries with us



The report includes an elaborative analysis of numerous factors affecting the global market. Information on trends, drivers, opportunities, threats, and restraints of the market can further help stakeholders gain valuable insights into the market. The report also offers a detailed competitive landscape by presenting information on key players, market share by manufacturers, and their strategies.


Report Scope & Segmentation






















































ATTRIBUTE



DETAILS



Study Period



2019-2030



Base Year



2022



Estimated Year



2023



Forecast Period



2023-2030



Historical Period



2019-2021



Growth Rate



CAGR of 6.9% from 2023-2030



Unit



Value (USD Billion), and Volume (Units)



Segmentation



By Type, By Application, and Region



By Type




  • Plastic Bottles

  • Glass Bottles



By Application




  • Intramuscular injection

  • Intravenous injection



 


 


By Geography


 




  • North America (By Type, Application, and Country)

    • U.S.

    • Canada



  • Europe (By Type, Application, and Country)

    • Germany

    • France

    • U.K.

    • Italy

    • Russia

    • Rest of Europe



  • Asia Pacific (By Type, Application, and Country)

    • China

    • Japan

    • South Korea

    • India

    • Australia

    • Taiwan

    • Indonesia

    • Thailand

    • Malaysia

    • Rest of the Asia Pacific



  • Latin America (By Type, Application, and Country)

    • Mexico

    • Brazil

    • Colombia

    • Argentina

    • Rest of Latin America



  • Middle East & Africa (By Type, Application, and Country)





    • Turkey

    • Saudi Arabia

    • UAE

    • Rest of the Middle East & Africa





Frequently Asked Questions

Fortune Business Insights says that the market stood at USD 3.24 billion in 2022.

Fortune Business Insights says that the market is projected to reach USD 5.48 billion by 2030.

The value of the North America market was USD 1.26 billion in 2022.

The market is projected to grow at a CAGR of 6.9% during the forecast period (2023-2030).

Based on type, the plastic bottles segment is the leading segment in the market.

An increase in the usage of normal saline for dehydration and sepsis and the growing number of hospital admissions and surgical procedures are the key factors driving the global market growth.

Baxter and Kelun Group are the top players in the global market.

Seeking Comprehensive Intelligence on Different Markets?
Get in Touch with Our Experts

Speak to an Expert
  • Oct, 2023
  • 2022
  • 2019-2021
  • 118

    CHOOSE LICENSE TYPE

  • $4850
    $5850
    $6850

Personalize this Research

  • Granular Research on Specified Regions or Segments
  • Companies Profiled based on User Requirement
  • Broader Insights Pertaining to a Specific Segment or Region
  • Breaking Down Competitive Landscape as per Your Requirement
  • Other Specific Requirement on Customization
Request Customization Banner

Healthcare Clients

Grifols
Galemed
Johnson
Siemens Healthineers
Fresenius

Client Testimonials

“This report is really well done and we really appreciate it! Again, I may have questions as we dig in deeper. Thanks again for some really good work.”

- U.S.-based biotechnology company focussing on treatment of chronic pain.

“Kudos to your team. Thank you very much for your support and agility to answer our questions.”

- Europe-based provider of solutions to automate data centre operations.

“We appreciate you and your team taking out time to share the report and data file with us, and we are grateful for the flexibility provided to modify the document as per request. This does help us in our business decision making. We would be pleased to work with you again, and hope to continue our business relationship long into the future.”

- India-based manufacturer of industrial and specialty intermediates with a strong global presence.

“I want to first congratulate you on the great work done on the Medical Platforms project. Thank you so much for all your efforts.”

- One of the largest cosmetics company in the world.

“Thank you very much. I really appreciate the work your team has done. I feel very comfortable recommending your services to some of the other startups that I’m working with, and will likely establish a good long partnership with you.”

- U.S. based startup operating in the cultivated meat market.

“We received the below report on the U.S. market from you. We were very satisfied with the report.”

- Global hearing aids manufacturer.

“I just finished my first pass-through of the report. Great work! Thank you!”

- U.S. based solar racking solutions provider.

“Thanks again for the great work on our last partnership. We are ramping up a new project to understand the imaging and imaging service and distribution market in the U.S.”

- World’s leading advisory firm.

“We feel positive about the results. Based on the presented results, we will do strategic review of this new information and might commission a detailed study on some of the modules included in the report after end of the year. Overall we are very satisfied and please pass on the praise to the team. Thank you for the co-operation!”

- Germany based machine construction company.

“Thank you very much for the very good report. I have another requirement on cutting tools, paper crafts and decorative items.”

- Japanese manufacturing company of stationery products.

“We are happy with the professionalism of your in-house research team as well as the quality of your research reports. Looking forward to work together on similar projects”

- One of the Leading Food Companies in Germany

“We appreciate the teamwork and efficiency for such an exhaustive and comprehensive report. The data offered to us was exactly what we were looking for. Thank you!”

- Intuitive Surgical

“I recommend Fortune Business Insights for their honesty and flexibility. Not only that they were very responsive and dealt with all my questions very quickly but they also responded honestly and flexibly to the detailed requests from us in preparing the research report. We value them as a research company worthy of building long-term relationships.”

- Major Food Company in Japan

“Well done Fortune Business Insights! The report covered all the points and was very detailed. Looking forward to work together in the future”

- Ziering Medical

“It has been a delightful experience working with you guys. Thank you Fortune Business Insights for your efforts and prompt response”

- Major Manufacturer of Precision Machine Parts in India

“I had a great experience working with Fortune Business Insights. The report was very accurate and as per my requirements. Very satisfied with the overall report as it has helped me to build strategies for my business”

- Hewlett-Packard

“This is regarding the recent report I bought from Fortune Business insights. Remarkable job and great efforts by your research team. I would also like to thank the back end team for offering a continuous support and stitching together a report that is so comprehensive and exhaustive”

- Global Management Consulting Firm

“Please pass on our sincere thanks to the whole team at Fortune Business Insights. This is a very good piece of work and will be very helpful to us going forward. We know where we will be getting business intelligence from in the future.”

- UK-based Start-up in the Medical Devices Sector

“Thank you for sending the market report and data. It looks quite comprehensive and the data is exactly what I was looking for. I appreciate the timeliness and responsiveness of you and your team.”

- One of the Largest Companies in the Defence Industry
We use cookies to enhance your experience. By continuing to visit this site you agree to our use of cookies . Privacy.
X