"Designing Growth Strategies is in our DNA"

Dermatophytic Onychomycosis Treatment Market Size, Share & Industry Analysis, By Product Type (Tablets and Nail Paints), By Route of Administration (Oral and Topical), By Type (Prescribed and Over-the-Counter (OTC)), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Channels), and Regional Forecast, 2024-2032

Last Updated: June 24, 2024 | Format: PDF | Report ID: FBI103310

 

KEY MARKET INSIGHTS

Play Audio Listen to Audio Version

The global dermatophytic onychomycosis treatment market size was valued at USD 4.97 billion in 2023 and is projected to grow from USD 5.34 billion in 2024 to USD 9.52 billion by 2032, exhibiting a CAGR of 7.5% during the forecast period (2024-2032). Onychomycosis (OM) is a fungal infection of the nail resulting in discoloration and thickening of the nail. It accounts for about one-third of the total fungal infections in the world. Furthermore, around 70%-80% of the total onychomycosis infections are caused by dermatophytes. This rising prevalence has resulted in an increasing demand for drugs used for dermatophytic onychomycosis treatment.



  • For instance, according to an NCBI article published in 2022, onychomycosis accounts for about 50% of nail diseases and is prevalent among 5.5% of the total population across the globe.


Moreover, the increasing prevalence of diabetes leads to high risks of developing nail fungus infections. According to research, the risk of developing onychomycosis increases with age; the rising geriatric population is the major factor driving the market growth. The increasing research, rapid adoption of nail lacquers, and rising new launches of generic drugs indicated for dermatophytic onychomycosis treatment are a few factors further expected to boost the global dermatophytic onychomycosis treatment market growth during the forecast period.


Onychomycosis is the most common nail disorder across the globe. Clinical examination, dermoscopy, and mycological examination are mostly recommended for all patients with suspected onychomycosis, which requires clinical visits. However, during the pandemic, the market witnessed a decline due to reduced patient visits and deferred diagnosis, owing to temporary closure of dermatology clinics.


Furthermore, the implementation of nationwide lockdown, stringent regulations for non-essential healthcare services, and shifted focus toward managing the increased COVID-19 cases negatively impacted the market growth.



  • For instance, according to an article published in 2021 by NCBI, there was a reduction in patient visits in many dermatology clinics in Turkey during the pandemic. The decrease in visits was observed among patients mainly suffering from superficial fungal infections, dermatoses, and others.


However, the market regained normalcy in the post-pandemic scenario, owing to the reopening of clinics and increased telemedicine usage by healthcare facilities to diagnose and provide treatment to patients suffering from dermatophytic onychomycosis.


Dermatophytic Onychomycosis Treatment Market Trends


Gradual Shift toward Topical Solutions is the Latest Trend


One of the major market trends is the growing preference for topical treatment solutions. Oral anti-fungal drugs are associated with liver damage and are not prescribed to patients with liver and heart diseases. As a result, effective topical treatments might be the preferred choice under certain conditions but not in all cases. On the other hand, the growing problem of anti-fungal resistance to existing oral drugs is one of the factors shifting the physician's preference toward topical drugs. According to a 2017 survey conducted by Moberg Pharma AB on dermatologists and podiatrists in the U.S., seven out of 10 doctors avoid prescribing oral terbinafine owing to the associated liver damage risk. Furthermore, dermatologists and podiatrists worldwide feel that there is a great need for better topical solutions than the existing ones. A gradual shift toward topical solutions has created significant market opportunities for topical drugs and has led to robust R&D for the development of effective nail lacquers.


Request a Free sample to learn more about this report.


Dermatophytic Onychomycosis Treatment Market Growth Factors


Rising Prevalence of Dermatophytic Onychomycosis to Drive the Market Growth


One of the key factors driving the growth of the market is the rising prevalence of onychomycosis. The prevalence of toenail onychomycosis infection is much higher than that of fingernails. The rising prevalence of nail fungal infections caused by dermatophytes and a considerable upsurge in the number of prescriptions for dermatophytic onychomycosis treatment are expected to fuel the market growth.


According to a press release by Moberg Pharma AB, around 10% of the general population across the globe is suffering from onychomycosis, with approximately 35 to 40 million Americans having nail fungus. This rising prevalence is expected to favor the market growth during the forecast period.


In addition, the rising prevalence of diabetes is another reason for the increasing occurrence of dermatophytic infection. As per the International Diabetes Federation, around 537 million adults aged between 20-79 years were living with diabetes in 2021, and the number is projected to increase to reach 643 million by 2030. Thus, the rising burden of diabetes among the population increases the risk of developing the infection, and is anticipated to surge the demand for dermatophytic onychomycosis drugs.  


Presence of Potential Pipeline Candidates to Foster the Market Growth


The rising prevalence of onychomycosis, as well as the lack of effective treatment, has encouraged significant R&D investment by pharmaceutical companies for the development of novel therapeutics. Currently, many available topical dermatophytic onychomycosis treatment solutions are unable to penetrate deep inside the nail bed, and thus cannot completely cure the infection. Thus, several companies are actively working to overcome this challenge by conducting research on compounds with deeper penetration into the nails for efficient and effective dermatophytic onychomycosis treatment.


For example, Hexima, a biotechnological company, is conducting a phase I/IIa clinical study on HXP124, a plant defensin anti-fungal molecule for the treatment of nail fungus. HXP124 has shown greater penetration rates when compared to Kerydin and Jublia.


Thus, the increased research spending and the launch of potential drug candidates are projected to provide significant momentum to the market.


RESTRAINING FACTORS


Lack of Awareness among Patients May Impede the Market Growth


The major factor hindering the market growth is the lack of awareness among the population regarding the infection. People usually neglect the symptoms such as thickening of the nails, decolorization, and separation of the nails from the nail bed caused due to dermatophytic onychomycosis infection. Due to this, the nail fungal infection remains undiagnosed. In addition, many people refrain from treatment or seeking doctor's help due to very limited awareness about the infection.


According to a study published in the NCBI in the year 2019, the adherence rate for oral and topical onychomycosis treatment is 45% and 24%, respectively. Poor adherence is due to long treatment duration and lack of awareness among the patients. Thus, the ignorance from patients has resulted in many people being left untreated, which, in turn, is restricting the growth of the market.


Dermatophytic Onychomycosis Treatment Market Segmentation Analysis


By Product Type Analysis


Nail Paints Segment to Dominate owing to Growing Jublia Uptake


Based on product type, the market is segmented into tablets and nail paints. The nail paints segment is estimated to dominate the market during the forecast period. The increasing adoption and growing preference toward topical nail lacquers when compared to oral anti-fungal drugs coupled with increasing uptake of Jublia, is expected to augment the segment growth during the forecast period. However, decreased sales of Clenafin, especially in Japan, owing to the COVID-19 pandemic, has negatively impacted the revenue of the nail paints segment.


The tablets segment is anticipated to grow considerably during the forecast period due to rising government efforts to switch to generic drugs for dermatophytic onychomycosis treatment. Furthermore, terbinafine and griseofulvin are considered to be gold standards among oral drugs for dermatophytic onychomycosis treatment. This is expected to favor the tablets segment growth during the forecast period.


To know how our report can help streamline your business, Speak to Analyst


By Route of Administration Analysis


Topical Segment to Dominate due to Significant R&D Investment for Drug Development


On the basis of route of administration, the market is segmented into oral and topical. The topical segment accounted for the maximum market share in 2023. The growth of the segment is mainly due to the fact that several companies are involved in the development of a topical formulation for the treatment of onychomycosis using the nano-delivery platform technology.  In addition, some of the pharmaceutical companies are submitting new drug applications for the topical anti-fungal treatment.  For instance, in January 2024, Vanda Pharmaceuticals was granted the U.S. FDA approval to move forward with an investigational new drug called VTR-297, which is a topical anti-fungal candidate intended for the treatment of onychomycosis.


On the other hand, oral drugs are associated with adverse side effects, such as liver damage, and thus many dermatologists and podiatrists prefer prescribing topical solutions for dermatophytic onychomycosis treatment. This, coupled with increasing research for the development of topical drugs, is expected to accelerate the growth of the tablets segment.  Oral medications have more cure rates, owing to higher penetration and higher effectiveness when compared to topical solutions, which is the primary reason responsible for the growth of the oral segment. However, as most oral antifungals can be taken only through prescription and people were avoiding hospital visits amid the COVID-19 pandemic, the revenue of the oral segment declined during 2020-2021.


By Type Analysis


Over-the-Counter Segment Dominated due to Surging Sales of Ciclopirox


Based on type, the market is bifurcated into prescribed and Over-the-Counter (OTC). The OTC segment dominated the market in 2023, mainly due to the gradual shift toward nail paints and increasing sales of ciclopirox for dermatophytic onychomycosis treatment.


Furthermore, the growing prevalence of onychomycosis, rising number of podiatrists, and presence of favorable health reimbursement policies are the major factors driving the prescribed segment expansion. However, reduction in hospital visits due to government’s stringent regulations to close the non-emergency outpatient department in hospitals during the pandemic has negatively impacted the prescribed segment growth, which was continued in 2020 and 2021.


By Distribution Channel Analysis


Retail Pharmacies Generated Maximum Revenue due to Rising Sales of OTC Drugs


By distribution channel, the market is segmented into online channels, retail pharmacies, and hospital pharmacies. The retail pharmacies segment generated maximum revenue in 2023 owing to increasing sales of OTC drugs and the rising prevalence of diabetes and fungal nail infection. In addition, the expansion of retail pharmacies in developing nations, launch of various retail pharmacy stores, and others are anticipated to accelerate the segment growth in the coming years.



  • For instance, in September 2022, Apollo Pharmacy, one of the prominent omnichannel pharmacy retailers in India, established its 5000th store in Chennai. Such factors are anticipated to increase patient access to onychomycosis drugs, supporting market growth.


Post the COVID-19 pandemic, there has been an increasing preference toward online pharmacies for procurement of medicines. This is expected to provide remarkable growth to the online channels segment during the forecast period. In addition, benefits such as no waiting lines, significant discounts offered by the e-pharmacy, and others also increase patients' shift toward these channels, which is expected to bolster the segment growth during the forecast period.


The hospital pharmacies segment is expected to expand considerably during the forecast period due to increasing number of privately owned clinics and rising number of dermatologists and podiatrists.


REGIONAL INSIGHTS


North America Dermatophytic Onychomycosis Treatment Market Size, 2023 (USD Billion)

To get more information on the regional analysis of this market, Request a Free sample


North America dominated the global dermatophytic onychomycosis treatment market share and was valued at USD 2.20 billion in 2023. Increasing number of prescriptions for onychomycosis, rising research, and surging demand for Jublia and Kerydin are the key factors for the growth of the market in North America. According to a press release by Moberg Pharma AB, the total number of annual prescriptions written for onychomycosis treatment in North America is around 5 million, which, in turn, is expected to drive the market growth in North America. Also, increasing submission of new drug applications to regulatory authorities is one of the additional factors responsible for the regional market’s growth. For instance, in April 2020, Bausch Health Companies Inc. announced that the U.S. FDA had given approval to its supplemental new drug application for JUBLIA (efinaconazole) topical solution. This drug is used for the treatment of dermatophytic onchomycosis.


The Europe onychomycosis treatment market is anticipated to grow owing to increasing prevalence of onychomycosis coupled with favorable health reimbursement policies in the region. The regional expansion can also be credited to the growing preferences for generic drugs and improved Over-the-Counter (OTC) drug distribution for dermatophytic onychomycosis treatment. According to the Journal of the European Academy of Dermatology and Venereology, onychomycosis prevalence in Europe is 4.3%. Thus, due to the above-mentioned factors, the market is expected to grow in Europe.


In Asia Pacific, the market is poised to grow at the fastest CAGR during the forecast period owing to new product launches, rising prevalence of diabetes, and increasing geriatric population. In March 2020, Kaken Pharmaceuticals Co., Ltd., a Japan-based pharmaceutical manufacturer, launched Jublia in Hong Kong. This launch and other factors are expected to foster the market growth in Asia Pacific.


Moreover, improving distribution channels, rising patient awareness, and increasing health expenditure are factors propelling the market growth in the rest of the world.


List of Key Companies in Dermatophytic Onychomycosis Treatment Market


Bausch Health Holds the Leading Position owing to High Jublia Sales


Bausch Health Companies, Inc. accounted for the largest global market share owing to higher sales of Jublia. The product has a cure rate of 15%-18% compared to other nail lacquers and exhibits minimal side effects compared to oral drugs for dermatophytic onychomycosis.


Furthermore, favorable health reimbursement for Jublia is the main reason for the company's dominant share. On the other hand, Pfizer is ranked second in the market due to increasing demand for Kerydin. However, the market share of both companies is estimated to decline due to the patent loss of Jublia, launch of generics, and the economic crises created by the COVID-19 pandemic.



  • For instance, in July 2021, Lupin launched Tavaborole Topical Solution, a generic equivalent to Kerydin Topical Solution in the U.S. The product was meant for the treatment of onychomycosis of the toenails caused by Trichophyton rubrum or Trichophyton mentagrophytes.


LIST OF KEY COMPANIES PROFILED:



KEY INDUSTRY DEVELOPMENTS:



  • December 2022: Bausch Health Companies Inc. announced the filing of a patent for a method aiming at treating onychomycosis. This patent filing has strengthen company's position in the global market.

  • July 2021 – Zydus Lifesciences received the U.S. FDA approval to market efinaconazole topical solution for the treatment of onychomycosis. Through this approval, the company strengthened its position across the country.

  • July 2021 – Almirall S.A. and Kaken Pharmaceutical entered into a license and distribution agreement in which Kaken Pharmaceutical granted exclusive rights to Almirall for the development and commercialization of topical antifungal efinaconazole in Europe. Through this move, Almirall S.A.  expanded its geographical footprint in Europe.

  • April 2021 – Aleor Dermaceuticals received tentative U.S. FDA approval for an efinaconazole topical solution intended for the treatment of fungal toenail infections.

  • March 2020 – Kaken Pharmaceuticals Co., Ltd. announced the Hong Kong launch of Jublia. Such launches are expected to expand the company’s geographical presence.

  • April 2020 – Bausch Health Companies Inc. received the U.S. FDA approval for a 10% topical solution, Jubila, to treat patients aged six years and above suffering from onychomycosis.


REPORT COVERAGE


An Infographic Representation of Dermatophytic Onychomycosis Treatment Market

To get information on various segments, share your queries with us



The market research report presents a comprehensive assessment of the global market by offering valuable insights, facts, industry-related information, and historical data. Furthermore, the report offers in-depth analysis and information as per market segments, helping our readers to get a comprehensive overview of the global market. It also provides various key insights such as pipeline analysis, regulatory & reimbursement overview, new product launches, and recent mergers, acquisitions, and partnerships.


To gain extensive insights into the market, Request for Customization


Report Scope & Segmentation










































ATTRIBUTE



DETAILS



Study Period



2019-2032



Base Year



2023



Estimated Year



2024



Forecast Period



2024-2032



Historical Period



2019-2022



CAGR



Growth rate of 7.5% from 2024 to 2032



Unit



Volume (K Units)



Segmentation



By Product Type



  • Tablets

  • Nail Paints


By Route of Administration



  • Oral

  • Topical


By Type



  • Prescribed

  • Over-the-Counter (OTC


By Distribution Channel



  • Hospital Pharmacies

  • Retail Pharmacies

  • Online Channels


By Geography



  • North America (By Product Type, By Route of Administration, By Type, By Distribution Channel, and By Country)

    • U.S.

    • Canada



  • Europe (By Product Type, By Route of Administration, By Type, By Distribution Channel, and By Country/Sub-region)

    • U.K.

    • Germany

    • France

    • Italy

    • Spain

    • Scandinavia

    • Russia

    • Rest of Europe



  • Asia Pacific (By Product Type, By Route of Administration, By Type, By Distribution Channel, and By Country/Sub-region)

    • Japan

    • China

    • India

    • Australia

    • New Zealand

    • Southeast Asia

    • Rest of Asia Pacific








Frequently Asked Questions

The value of the global market was USD 4.97 billion in 2023.

Fortune Business Insights says that the market value is projected to reach USD 9.52 billion by 2032.

The value of the market in North America was USD 2.20 billion in 2023.

The market is projected to record a CAGR of 7.5% during the forecast period of 2024-2032.

The nail paints segment is the leading segment in the market.

The rising prevalence of dermatophytic onychomycosis and the presence of potential pipeline candidates are the key factors driving the market growth.

Bausch Health Companies Inc. and Pfizer Inc. are the major players in the market.

North America is expected to hold the largest market share during the forecast period.

The gradual shift toward topical treatment options is the key trend in the market.

Seeking Comprehensive Intelligence on Different Markets?
Get in Touch with Our Experts

Speak to an Expert
  • 2019-2032
  • 2023
  • 2019-2022
  • 136

Personalize this Research

  • Granular Research on Specified Regions or Segments
  • Companies Profiled based on User Requirement
  • Broader Insights Pertaining to a Specific Segment or Region
  • Breaking Down Competitive Landscape as per Your Requirement
  • Other Specific Requirement on Customization
Request Customization Banner

Client Testimonials

“We are quite happy with the methodology you outlined. We really appreciate the time your team has spent on this project, and the efforts of your team to answer our questions.”

- One of the largest & renowned medical research centers based in the U.S. on a report on the U.S. NIPT Market.

“Thanks a million. The report looks great!”

- Feedback from a consultant on a report on the U.S. Beef Market.

“Thanks for the excellent report and the insights regarding the lactose market.”

- Brazil based company specializing in production of protein ingredients.

“I liked the report; would it be possible to send me the PPT version as I want to use a few slides in an internal presentation that I am preparing.”

- Global Digital Services Agency on a report on the Global Luxury Goods Market.

“This report is really well done and we really appreciate it! Again, I may have questions as we dig in deeper. Thanks again for some really good work.”

- U.S.-based biotechnology company focussing on treatment of chronic pain.

“Kudos to your team. Thank you very much for your support and agility to answer our questions.”

- Europe-based provider of solutions to automate data centre operations.

“We appreciate you and your team taking out time to share the report and data file with us, and we are grateful for the flexibility provided to modify the document as per request. This does help us in our business decision making. We would be pleased to work with you again, and hope to continue our business relationship long into the future.”

- India-based manufacturer of industrial and specialty intermediates with a strong global presence.

“I want to first congratulate you on the great work done on the Medical Platforms project. Thank you so much for all your efforts.”

- One of the largest cosmetics company in the world.

“Thank you very much. I really appreciate the work your team has done. I feel very comfortable recommending your services to some of the other startups that I’m working with, and will likely establish a good long partnership with you.”

- U.S. based startup operating in the cultivated meat market.

“We received the below report on the U.S. market from you. We were very satisfied with the report.”

- Global hearing aids manufacturer.

“I just finished my first pass-through of the report. Great work! Thank you!”

- U.S. based solar racking solutions provider.

“Thanks again for the great work on our last partnership. We are ramping up a new project to understand the imaging and imaging service and distribution market in the U.S.”

- World’s leading advisory firm.

“We feel positive about the results. Based on the presented results, we will do strategic review of this new information and might commission a detailed study on some of the modules included in the report after end of the year. Overall we are very satisfied and please pass on the praise to the team. Thank you for the co-operation!”

- Germany based machine construction company.

“Thank you very much for the very good report. I have another requirement on cutting tools, paper crafts and decorative items.”

- Japanese manufacturing company of stationery products.

“We are happy with the professionalism of your in-house research team as well as the quality of your research reports. Looking forward to work together on similar projects”

- One of the Leading Food Companies in Germany

“We appreciate the teamwork and efficiency for such an exhaustive and comprehensive report. The data offered to us was exactly what we were looking for. Thank you!”

- Intuitive Surgical

“I recommend Fortune Business Insights for their honesty and flexibility. Not only that they were very responsive and dealt with all my questions very quickly but they also responded honestly and flexibly to the detailed requests from us in preparing the research report. We value them as a research company worthy of building long-term relationships.”

- Major Food Company in Japan

“Well done Fortune Business Insights! The report covered all the points and was very detailed. Looking forward to work together in the future”

- Ziering Medical

“It has been a delightful experience working with you guys. Thank you Fortune Business Insights for your efforts and prompt response”

- Major Manufacturer of Precision Machine Parts in India

“I had a great experience working with Fortune Business Insights. The report was very accurate and as per my requirements. Very satisfied with the overall report as it has helped me to build strategies for my business”

- Hewlett-Packard

“This is regarding the recent report I bought from Fortune Business insights. Remarkable job and great efforts by your research team. I would also like to thank the back end team for offering a continuous support and stitching together a report that is so comprehensive and exhaustive”

- Global Management Consulting Firm

“Please pass on our sincere thanks to the whole team at Fortune Business Insights. This is a very good piece of work and will be very helpful to us going forward. We know where we will be getting business intelligence from in the future.”

- UK-based Start-up in the Medical Devices Sector

“Thank you for sending the market report and data. It looks quite comprehensive and the data is exactly what I was looking for. I appreciate the timeliness and responsiveness of you and your team.”

- One of the Largest Companies in the Defence Industry
We use cookies to enhance your experience. By continuing to visit this site you agree to our use of cookies . Privacy.
X