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The global transplantation market size was USD 5.47 billion in 2020. The global impact of COVID-19 has been unprecedented and staggering, with transplants witnessing a negative demand shock across all regions amid the pandemic. Based on our analysis, the global market exhibited a huge decline of -52.5% in 2020 as compared to the average year-on-year growth during 2017-2019. The market is projected to grow from USD 7.24 billion in 2021 to USD 14.67 billion in 2028, growing at a CAGR of 10.6% in the 2021-2028 period. The sudden rise in the growth rate is attributable to this market’s demand and growth, returning to pre-pandemic levels once the pandemic is over.
Over the past years, there has been increasing awareness regarding organ donation and registration. The widespread popularity of organ registration is projected to influence the market dynamics positively. Coupled with this, the rising prevalence of chronic diseases is further estimated to surge market growth in the coming years. In addition, support from government organizations has primarily helped the acceptance of organ donor registration. However, there is still a huge gap between organ donors and organ recipients' demand and supply. However, the technological advancements in organ transplant surgeries are projected to reduce this supply-demand gap slowly.
The Outbreak of COVID-19 Pandemic to Reduce Demand for Transplant Surgeries Worldwide
The sudden outbreak of coronavirus at the beginning of 2019 has left the global healthcare system in a huge dilemma. The overwhelming coronavirus patient admission in public and private hospitals has compelled governing bodies to delay elective and non-urgent surgeries in hospitals and ambulatory care centers. This has widely impacted this market globally. The pandemic has also led to a lower number of registers for organ transplant surgeries worldwide. The COVID-19 infection has also led to large rejections of organs from transplant donors. In May 2020, the Italian National Authority for Transplantation released a document guiding that all donor patients must be tested negative for SARS-CoV-2, and potential positive donor organs have to be discarded.
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Active Initiatives by Government and Non-Government Organizations to Increase Donor Lists
There is a massive gap in the demand and supply of organ transplant recipients and donors. This gap has led to an increase in NGOs’ and government bodies' involvement to increase awareness regarding registering for organ donation. Additionally, campaigns endorsed by celebrities have also gained traction among NGOs to increase donor registers across the globe. For instance, organ donation pledges in India grew by an astounding 16,500% in 2018 owing to endorsements and organ donation pledges by popular Bollywood actors such as Aamir Khan and Priyanka Chopra.
Increasing Prevalence of Chronic Diseases to Propel Growth
Growing prevalence and incidence of chronic diseases such as cancer, kidney failure, COPD, and lupus frequently lead to catastrophic damage to tissue and organs. According to the American Lung Association, over 9 million adults over 18 suffered from chronic bronchitis in the U.S in the year 2018. Additionally, the organization also states that in 2018 over 200,000 new lung cancer cases were recorded in the U.S.
An upsurge in organ failure has resulted in a growth in demand for transplant procedures. According to the American Journal of Lung Transplantation, the number of lung transplant surgeries in the U.S reached a record high of more than 200 in the year 2017. There was a growth of 133 lung transplants from the previous year. Consecutively, all these factors are estimated to augment the transplantation market growth in the upcoming years.
Technological Advancements in Transplant Surgeries to Boost Market Potential
According to the U.S Government's information on organ donation and transplantation, there are currently more than 107,000 men, women, and children on the national transplant waiting list as of February 2021. The increasing burden of the patient number, demanding an organ/tissue transplant, is compelling researchers worldwide to bring alternatives for organ replacement surgeries.
A new 3D printing technology focused on printing an organ/tissue precisely like the one inside the body has emerged in the transplantation industry, which is anticipated to revolutionize the market. For instance, a bioprinting company REGEMAT 3D has more than 60 active projects worldwide, and the company has its presence in over 20 countries around the globe. It has also continued its expansion in Colombia by setting up its new headquarters. Therefore, medical devices' technological advancements are anticipated to provide substantial growth opportunities for the market during the forecast period.
Shortage of Organs for the Treatment of Organ Failure to Restrict Market Growth
Globally, the scarcity of organs is the main problem. Organ donors are relatively less as compared to patients waiting for organ transplant surgery. For Instance, according to the United Network for Organ Sharing (UNOS), in 2019, in the U.S., around 115,000 people are waiting for organ transplants. Thus, the dearth of donors means 20 persons decrease each day in the U.S. while waiting for a life-saving organ transplant. There is a massive gap in the demand and supply of organs for transplant surgery. Consecutively, all the above factors are likely to hamper the market growth.
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Tissue Segment to Dominate Backed by Advent of Unique Products
Based on the segmentation of the market by product type, the division includes tissue products, immunosuppressive drugs, and preservation solutions. The tissue segment held the majority of the transplantation market share in 2020. Factors such as the advent of new, improved products offer enhanced treatment. Such products include Chondrofix Osteochondral Allograft, DeNovo NT Graft, and DuraMatrix Collagen Dura Substitute Membrane. Hence, the accessibility of such progressive products and techniques is anticipated to spur market growth.
On the other hand, the immunosuppressive drugs segment is expected to emerge as the fastest-growing segment during the projected period owing to the growing adoption of these drugs to prevent post-transplant organ or tissue rejection. Besides, the preservation solutions segment is anticipated to show substantial growth. Several government initiatives to fund stem cell research and several awareness programs are attributed to the segment's development. Moreover, an upsurge in organ failure cases and growing demand for transplant procedures are likely to aid the market growth.
Tissue Transplant Segment to Lead Fueled by Rising Number of Road Accidents
Based on application, the market is segmented into organ transplant and tissue transplant. The tissue transplant segment holds a dominant share in the market during the projected time frame. The dominance is due to the conductance of a large number of tissue replacements. In addition, the rise in the number of road accidents coupled with burn cases is likely to boost the demand for tissue products. For Example, Gemeinnützige Gesellschaft Gmbh, a non-profit organization, has carried out over 5,500 tissue transplants in Germany in the year 2018.
On the flip side, the organ transplant segment is estimated to witness a significant CAGR from 2021-2028. Factors such as the growing usage of immunosuppressive drugs and a rise in organ transplant procedures are anticipated for the segment's growth. For Instance, according to the Mayo Clinic, around 8,000 liver transplant surgeries were carried out in the U.S in the year 2017.
Surging Number of Transplant Procedures to Assist Growth of Hospitals Segment
In terms of the end-user, the market is segmented into hospitals, transplantation centers, and others. The hospital segment holds the lion’s share globally due to a larger number of transplants in these facilities. In addition, factors such as the availability of well-established databases for organ obtainability in most hospitals are likely to boost the market growth. Besides, the transplantation centers are expected to grow and witness the highest CAGR during the forecast period. Factors attributed to their growth include growing demand for transplantation procedures in advanced healthcare centers with innovative techniques.
Moreover, the government's initiatives to boost organ donation are estimated to drive the segment's growth. For Instance, the NHS carries out regular public awareness drives in the U.K to educate people on registering for organ donation. In 2019, the NHS Blood and Transplant unit launched a yearlong awareness campaign to increase organ donor registers.
The other segment is expected to witness moderate growth over the forecast period due to the lesser availability of well-developed infrastructure in emerging countries and other developing countries.
North America Transplantation Market Size, 2020 (USD Billion)
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The market size in North America stood at USD 2.29 billion in 2020. The dominance of this region is attributable to a well-developed healthcare infrastructure coupled with leading players in the region. Another major factor attributed to the region's growth is the launch of novel products in the region. In November 2020, Lupin launched Tacrolimus immunosuppressive drug in partnership with Concord Biotech in the U.S. Europe holds the second-largest market position due to its investments in R&D for the activities. This, together with the large patient population in the region, is likely to drive growth during the forecast period.
Moreover, Asia Pacific is projected to witness the highest CAGR due to the growing number of chronic diseases and the region's rising geriatric populace. According to the World Bank, Besides, Latin America, the Middle East, and Africa are likely to witness moderately slower growth due to the lesser adoption of high-cost transplants in most under-developed countries.
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Significant R&D Investments by Key Players to Improve Business Outcome
The market is highly fragmented due to key players' presence varying from start-ups to well-established ones. The key players driving the market are focused on developing novel products to attain effective transplant procedures. Moreover, partnerships, mergers, and acquisitions support merchants in growing their current product portfolio and geographical reach. For instance, in September 2020, CollPlant Biotechnologies announced the collaboration expansion of United Therapeutics Corporation.
An Infographic Representation of Transplantation Market
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The global market research report provides a detailed analysis of the market. It focuses on key aspects such as leading companies, product types, product applications, and end-users. Besides this, the report offers insights into the market trends and highlights key industry developments. In addition to the aforementioned factors, the report encompasses several factors that have contributed to the growth of the developed market in recent years.
Value (USD Billion)
Product Type; Application; End User; and Region
By Product Type
Fortune Business Insights says that the global market size was USD 5.47 billion in 2020 and is projected to reach USD 14.67 billion by 2028.
In 2020, the North American market size stood at USD 2.29 billion.
Registering a CAGR of 10.6%, the market will exhibit strong growth in the forecast period (2021-2028).
The tissue products segment is expected to lead the market during the forecast period.
The growing number of transplantation procedures globally and the introduction of advanced products by renowned players are major factors driving the market's growth.
TransMedics Inc., Care Dx, and AbbVie Inc. are the major players in the global market.
North America dominated the market in terms of share in 2020.
The increased demand for technologically advanced products is expected to drive the adoption of transplant surgeries.
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