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Orthobiologics Market Size, Share and Global Trend by Product Type (Viscosupplements, Bone Growth Stimulators, Demineralized Bone Matrix, Synthetic Bone Substitutes, Stem Cells, Allografts), Application (Spinal Fusion, Maxillofacial & Dental, Soft Tissue Repair, Reconstructive & Fracture Surgery), End User (Hospitals, Ambulatory Surgical Centers, Speciality Clinics) and Geography Forecast till 2026

Region : Global | Latest Update: Jul, 2019 | Published Date: Apr, 2019 | Report ID: FBI100173| Status : Published



The Global Orthobiologics Market was valued at US$ 5,830.1 Mn in 2018 and is estimated to reach US$ 8,261.6 Mn by the end of 2026, exhibiting a CAGR of 4.5% The economic burden due to orthopedic injuries and osteoarthritis is increasing at a significant rate. According to the Centers for Disease Control and Prevention, over 30 Mn people in the U.S. are affected by osteoarthritis, making it a major concern for healthcare providers. Orthobiologics have considerably impacted orthopedic surgeries.

Orthobiologics, which was earlier used for regenerative medicines, has now expanded its area of application to spinal fusion, dental, maxillofacial, cartilage repair, knee arthroscopies and many others. Owing to the increasing demand and rapid adoption of the newly introduced products such as Medtronic’s Infuse, a bone morphogenetic protein, are primary reasons for the surge in orthobiologics markets.

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Viscosupplements to Dominate the Global Orthobiologics Market 

Belonging to the first generation of orthobiologics, viscosupplements dominated the orthobiologics market in 2018 with a share of 32.1% in the global market. Viscosupplements are injections of hyaluronic acid, which are directly administered into the joints. Viscosupplements are extensively used in the treatment of knee osteoarthritis, which is one of the major problems among the geriatric population. High product costs, entries of the new manufacturers, and recent marketing approvals are the factors attributed to the expansion of viscosupplements. Furthermore, improving reimbursement guidelines for viscosupplements are also favoring the viscosupplements segments.

In terms of applications, the orthobiologics market is categorized into spinal fusion, maxillofacial & dental, soft tissue repair, reconstructive & fracture surgery, and others. Spinal fusion accounted for the highest market share in 2018, owing to the increased use of synthetic matrices and allografts in spine fusion surgeries. Soft tissue repair segment witnessed the highest growth due to the increased cases of sports injuries and demand for orthobiologics for cartilage repair. Hospitals, ambulatory surgical centres, and speciality clinics are the major end users of the orthobiologics products.

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Growing Trend of Orthopedic Surgery in Outpatient Settings to Favor North America Orthobiologics Market

The orthobiologics market in North America was valued at US$ 2,326.2 Mn in 2018 and is estimated to dominate the market throughout the forecast period. Business strategies of leading manufacturers in the U.S., favorable reimbursement policies, increasing prevalence of degenerative bone diseases and growing trend of orthopedic surgeries in outpatient settings are the factors that may boost the orthobiologics market in North America during 2019-2026. In terms of revenues, Europe is projected to be the second dominant region with a significant share in the global orthobiologics market owing to the new marketing approval for Cingal, a viscosupplements in Europe. Asia Pacific is expected to register the highest CAGR during the forecast period which is attributable to the increasing demand for viscosupplements in India and rising number of standalone orthopedic clinics. 

North America Orthobiologics Market, 2018

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Medtronic and Sanofi Account to lead the Orthobiologics Market

Medtronic has emerged as the leading player in the global orthobiologics market mainly due to the successful launch and rapid adoption for Infuse bone morphogenetic protein. Medtronic is estimated to hold the highest share in the forecast duration owing to the higher cost and strong sales force for Infuse and FDA approval received for the use of Infuse in new spine surgery indication in April 2018. Other players operating in the global orthobiologics market are DePuy Synthes (Johnson & Johnson Services, Inc.), Stryker, Zimmer Biomet, Sea Spine, Bioventus, RTI Surgical Holdings, Inc., Musculoskeletal Transplant Foundation, Wright Medical Group N.V., and Anika Therapeutics, Inc.

Report Overview 

Rising number of soft tissue injuries, reconstructive and regenerative surgeries have resulted in increased demand for orthobiologic products. Orthobiologics are the products that are used during surgeries to aid quick healing of orthopedic injuries. Orthobiologics are made from products ranges from growth stimulators to synthetic bone substitutes.

The report provides qualitative and quantitative insights on the orthobiologics industry and detailed analysis of market size and growth rate for all possible segments in the market. The market is segmented based on product type, application, end user, and geography. In terms of product type, the global orthobiologics market is segmented into viscosupplements, bone growth stimulators (Bone Morphogenetic Proteins and Platelet-Derived Growth Factors), demineralized bone matrix (DBM), synthetic bone substitutes, stem cells, allografts, and others. On the basis of application, the market is categorized into spinal fusion, maxillofacial & dental, soft tissue repair, reconstructive & fracture surgery, and others. The end users for orthobiologic products includes hospitals, ambulatory surgical centres, and specialty clinics. Geographically, the market is segmented into five major regions, which are North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The regions are further categorized into countries.

Along with this, the report provides elaborative analysis of the market dynamics and competitive landscape. Various key insights provided in the report are the prevalence of soft tissue injuries for key countries, number of spinal fusion surgery for key countries, regulatory scenario in key countries, new product launch, key mergers and acquisitions. recent industry developments, and others.

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By Product Type

·      Viscosupplements

·      Bone Growth Stimulators

o    Bone Morphogenetic Proteins (BMP)

o    Platelet-Derived Growth Factors

·      Demineralized Bone Matrix (DBM)

·      Synthetic Bone Substitutes

·      Stem Cells

·      Allografts

·      Others

By Application

·      Spinal Fusion

·      Maxillofacial & Dental

·      Soft Tissue Repair

·      Reconstructive & Fracture Surgery

·      Others

By End User

·      Hospitals

·      Ambulatory Surgical Centers

·      Speciality Clinics

By Geography

·      North America (USA and Canada)

·      Europe (UK, Germany, France, Italy, Spain, Scandinavia and Rest of Europe)

·      Asia Pacific (Japan, China, India, Australia, Southeast Asia and Rest of Asia Pacific)

·      Latin America (Brazil, Mexico and Rest of Latin America)

·      Middle East & Africa (South Africa, GCC and Rest of Middle East & Africa)


  • Zimmer Biomet
  • Genzyme Corporation (Sanofi)
  • DePuy Synthes (Johnson & Johnson Services, Inc.)
  • Stryker
  • Medtronic
  • Wright Medical Group N.V.
  • Anika Therapeutics, Inc.
  • SeaSpine
  • Bioventus
  • RTI Surgical Holdings, Inc.
  • Musculoskeletal Transplant Foundation
  • Other players

Orthobiologics Market Size, Share and Global Industry Trend Forecast till 2026
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