"Designing Growth Strategies is in our DNA"

Anti-Inflammatory Biologics Market Size, Share & COVID-19 Impact Analysis, By Drug Class (Anti-Tumor Necrosis Factor (TNF), Interleukin Antagonists, Janus Kinase (JAK) Inhibitors, and Others), By Application (Rheumatoid Arthritis, Psoriasis, and Others), By Route of Administration (Oral and Injection (Subcutaneous and Intravenous)), By Distribution Channel (Hospital Pharmacy, Retail Pharmacy, and Online Pharmacy), and Regional Forecast, 2023-2030

Last Updated: May 13, 2024 | Format: PDF | Report ID: FBI102733

 

KEY MARKET INSIGHTS

Play Audio Listen to Audio Version

The anti-inflammatory biologics market size was valued at USD 93.13 billion in 2022 and is projected to grow from USD 93.32 billion in 2023 to USD 139.80 billion by 2030, exhibiting a CAGR of 5.9% during the forecast period.


Anti-inflammatory biologics is an emerging treatment for autoimmune inflammatory diseases. The prevalence of inflammatory diseases, such as psoriasis, ulcerative colitis, rheumatoid arthritis, and inflammatory bowel diseases is increasing and so is the demand for biologics. Continuous research on anti-Tumor Necrosis Factor (TNF), interleukin antagonists, Janus Kinase (JAK) inhibitors are adding to the number of potential drug candidates waiting for approval or in the clinical stage.


COVID-19 IMPACT


COVID-19 Positively Affected Market Revenue Due to High Sales of the Biologics


The COVID-19 pandemic is anticipated to positively impact the anti-inflammatory therapeutics market due to the severe inflammation induced by SARS-CoV-2. The coronavirus triggers anti-inflammatory pneumonia, particularly in severe COVID-19 cases.


The increased awareness of inflammation's role has spurred increased research and development, leading to the repurposing of existing anti-inflammatory drugs and the development of novel treatments. Market players operating in the market have experienced a growth in their biologics revenue in 2020 compared to 2019 due to the increased adoption of biologics during the pandemic.



  • For instance, in 2020, Regeneron Pharmaceuticals Inc. generated a revenue of USD 270.0 million for its drug, Kevzara, experiencing a growth of 39.0% compared to 2021.


Furthermore, the pandemic's influence on healthcare delivery has extended to the adoption of telemedicine. This shift has positively impacted this market by improving patient access to treatments.


In 2021 & 2022, the market is expected to grow at a slower pace compared to 2020. Furthermore, the loss of patent protection for various biologics is another reason for the slower growth of the market in 2021 & 2022.


Anti-Inflammatory Biologics Market Trends


Transition from Anti-Tumor Necrosis Factor (TNF) to Non-Anti-Tumor Necrosis Factor (TNF) to Treat Inflammatory Diseases


In recent years, patients of inflammatory diseases have stopped responding to anti-TNF treatments and are going for non-anti TNF therapies, such as Janus Kinase (JAK) and interleukin inhibitors. The transition is attributed to the various benefits associated with Non-Anti-Tumor Necrosis Factor.


The JAK inhibitors offer a novel mechanism of action, targeting the Janus Kinase pathway involved in the regulation of the immune response. This provides an alternative therapeutic approach for patients who do not respond adequately to TNF inhibitors or experience adverse effects.


Furthermore, the convenience of oral administration with JAK inhibitors as compared to that of injectable TNF inhibitors appeals to both patients and healthcare providers. This ease of use enhances patient adherence and overall treatment compliance.


The market players are also focusing on the development of these Non-Anti-Tumor Necrosis Factors. This has created a large volume of clinical evidence supporting the effectiveness and safety of JAK inhibitors and interleukin inhibitors, which is increasing their adoption.


Request a Free sample to learn more about this report.


Anti-Inflammatory Biologics Market Growth Factors


Rising Prevalence of Inflammatory Diseases to Favor Market Growth


Increasing prevalence of autoimmune inflammatory diseases, such as psoriasis, rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel diseases, ulcerative colitis, and others is a major factor driving the market growth. For instance, according to a study published by the NCBI in August 2021, the prevalence of psoriasis in adults aged 20 years or older was 3% in the U.S. This factor is anticipated to foster the market progress during the forecast period. In addition to this, the rapid adoption of biologics for the treatment of inflammatory diseases as well as favorable reimbursement for biological therapies is expected to favor the market growth.


Increasing Number of Potential Pipeline Candidates to Boost Market Development


Many pharmaceutical giants are actively investing in research activities for the development of biologics. This has led to an increased presence of potential drug candidates in clinical trials. The expected launch of these potential pipeline candidates is projected to provide a significant boost to the market growth. With the advent of monoclonal antibodies and technological advancements, novel biological therapies can be developed to have anti-inflammatory action. For example, in December 2019, UCB S.A. announced positive results from the phase 3 clinical study of Bimekizumab for the treatment of psoriasis. Apart from this, research to expand the application of existing biologics to other rare anti-inflammatory diseases, such as lupus, diffuse systemic sclerosis, and others is likely to augment the adoption of anti-inflammatory biologics.


RESTRAINING FACTORS


Lack of Inclination for Biologics as First Line of Treatment to Restrict Market Growth


Despite anti-inflammatory biologics being highly effective in the treatment of psoriasis and rheumatoid arthritis, lack of preference for them, and growing inclination toward Disease-Modifying Anti-Rheumatic Drugs (DMARDs) are the key reasons for hampering the market growth. DMARDs, such as methotrexate is used as the first line of treatment for rheumatoid arthritis. Similarly, in the case of psoriasis, topical drugs, such as corticosteroids and vitamin D analogues are used as the first line of treatment. In comparison, anti-inflammatory biologics are used as the third line of treatment for both the diseases. This factor is expected to reduce the patient pool for these drugs, in turn negatively impacting the market growth.


Anti-Inflammatory Biologics Market Segmentation Analysis


By Drug Class Analysis


Interleukin Antagonist accounted for the Largest Share owing to Increase Prevalence of Inflammatory Condition


Based on drug class, the market is segmented into Anti-Tumor Necrosis Factor (TNF), interleukin antagonists, Janus Kinase (JAK) inhibitors, others.


Interleukin Antagonist held the largest share in the market in 2022. The growth is attributed to its efficacy in treating inflammatory conditions, growing patient preference for targeted therapies, and continuous research and development to introduce the novel drugs.


The Anti-Tumor Necrosis Factor (TNF) segment accounted for a substantial anti-inflammatory biologics market share in 2022. The segment’s growth can be attributed to the robust sales of Humira and rising prevalence of inflammatory bowel disease and other related diseases. Furthermore, the segment is expected to benefit from the high sales of drugs, such as Remicade as they are approved for treating a broader category of inflammatory diseases as compared to other drug classes, which are approved for limited disease indications.


The Janus Kinase (JAK) inhibitors segment is gradually gaining the market share owing to increased research activities and new product launches.



  • For instance, in December 2021, AbbVie announced that the U.S. FDA had approved RINVOQ for the treatment of adults suffering from active Psoriatic Arthritis (PsA). A significant increase in the revenue of RINVOQ is expected to fuel the JAK inhibitors segment growth.


Furthermore, the segment is poised to expand owing to the rising prevalence of rheumatoid arthritis and growing adoption of monoclonal antibodies.


To know how our report can help streamline your business, Speak to Analyst


By Application Analysis


Other Applications Gained a Major Traction Due to Growing Prevalence of Chronic Diseases


Based on application, the market is segmented into rheumatoid arthritis, psoriasis, and others.


In 2022, the others segment held the highest market share owing to significant research investments, strategic partnerships, and new product launches. Other factors responsible for the expansion of this segment include the presence of potential pipeline candidates and increasing incidence of ulcerative colitis, Crohn’s disease, and ankylosing spondylitis.


The rheumatoid arthritis segment generated substantial revenue in 2022. Primary reasons for the growth of the segment are the rising prevalence of rheumatoid arthritis and availability of more anti-inflammatory biologics for this disease.



  • According to the U.S. Centers for Disease Control and Prevention, 78 million adults in the U.S. are estimated to have doctor-diagnosed arthritis by 2040. This is estimated to further fuel the segment’s growth.


By Route of Administration Analysis


Injection to Become Primary Route of Administration Owing to Presence of Key Products


On the basis of route of administration, the market is segmented into oral and injection. The injection segment can be further bifurcated into subcutaneous and intravenous.


The injection segment is estimated to dominate the market throughout the forecast period. A vast majority of the anti-inflammatory biologics are administrated via the subcutaneous or intravenous route, which is the primary reason for the dominance of this segment.


The oral segment is anticipated to record a substantial CAGR owing to the market players’ increased focus on introducing oral biologics and higher sales of products, such as Xeljanz (tofacitinib) and Otezla (apremilast).


By Distribution Channel Analysis


Hospital Pharmacy Emerged as a Primary Distribution Channel Due to High Patient Volumes in Hospitals


In terms of distribution channel, the market is segmented into hospital pharmacy, retail pharmacy, and online pharmacy.


The hospital pharmacy segment generated the maximum revenue in 2022, which can be attributed to the increasing adoption of monoclonal antibodies, rising prevalence of inflammatory diseases, and favorable health reimbursement policies.


The retail pharmacy segment is poised to grow steadily due to the increasing number of pharmacies and rising prescriptions for biologics. The online pharmacy segment is likely to grow at a healthy pace owing to increasing disposable income, active government support, and rapid adoption of e-commerce platforms.


REGIONAL INSIGHTS


North America Anti-Inflammatory Biologics Market Size, 2022 (USD Billion)

To get more information on the regional analysis of this market, Request a Free sample


The market size in North America, holding the largest regional share, was valued at USD 59.37 billion in 2022. Significant increase in the demand for anti-TNF drugs and potential pipeline candidates are the primary factors accelerating the growth of the market in North America. Moreover, strategic position of key the players and high sales of their drugs in the region are estimated to augment the market’s expansion in North America.


Europe held the second-highest market share in 2022 and is anticipated to record a substantial CAGR during the forecast period. Significant R&D investments and increasing focus of market players on the introduction of new drugs in the region are expected to boost the demand for anti-inflammatory biologics during the forecast timeframe.


The market in Asia Pacific is predicted to record the fastest CAGR during the forecast period. The market’s growth in the region is attributed to the rising prevalence of various inflammatory disorders and growing awareness regarding the treatment options available for these diseases.


In Latin America and the Middle East & Africa, the market is projected to grow due to the huge unmet needs of the patient population, improving healthcare reforms, and rising disposable income.


List of Key Anti-Inflammatory Biologics Market Companies


AbbVie Accounted for Leading Market Share Owing to Presence of Key Products in Its Portfolio


In terms of market revenue, AbbVie accounted for the leading position in the market. Higher sales of Humira, significant research investments, and established market presence are the factors responsible for the dominant share of the company in the market. Moreover, AbbVie is continuously focusing on the introduction of advanced drugs in the drug class other than Anti-Tumor Necrosis Factor (TNF), which is expected to increase its revenue in the market in the future.


Furthermore, market players, such as Pfizer Inc. Amgen Inc., Biogen, UCB S.A., and others are also having a prominent position in the market due to their high focus on the development of novel drugs. Additionally, these companies are focusing on obtaining the regulatory approvals for their drugs by reputed agencies, such as the U.S. FDA to treat inflammatory diseases.


LIST OF KEY COMPANIES PROFILED:



  • AbbVie Inc. (U.S.)

  • Merck & Co., Inc. (U.S.)

  • Bristol-Myers Squibb Company (U.S.)

  • Johnson & Johnson Services, Inc. (U.S.)

  • Pfizer Inc. (U.S.)

  • Novartis AG (Switzerland)

  • UCB S.A. (Belgium)

  • Eli Lilly and Company (U.S.)

  • Amgen Inc. (U.S.)

  • Biogen (U.S.)


KEY INDUSTRY DEVELOPMENTS:



  • February 2023 - Pfizer Inc. announced the approval of its supplemental New Drug Application (sNDA) for CIBINQO by the U.S. FDA for patients suffering from moderate-to-severe atopic dermatitis.

  • March 2022 - AbbVie announced the U.S. FDA’s approval of RINVOQ (upadacitinib) for the treatment of adults suffering from ulcerative colitis.

  • October 2022 - GSK plc provided an update on the ContRAst phase III program for otilimab, an investigational monoclonal antibody used in the potential treatment of moderate to severe rheumatoid arthritis.

  • September 2022 - Bristol Myers Squibb announced two-year results from the POETYK PSO Long-Term Extension (LTE) trial with continuous Sotyktu treatment in adult patients diagnosed with plaque psoriasis.

  • December 2021: Pfizer Inc. announced the approval of Cibinqo (abrocitinib), an oral, once-daily, Janus Kinase 1 (JAK1) inhibitor, for the treatment of Atopic Dermatitis (AD) by the European Commission (EC).


REPORT COVERAGE


An Infographic Representation of Anti-Inflammatory Biologics Market

To get information on various segments, share your queries with us



The global anti-inflammatory biologics market report offers a detailed analysis of various factors affecting the market. These include growth drivers, restraints, opportunities, threats, and key industry developments. In addition to this, the report helps in analyzing, segmenting, and defining the market based on different segments, such as drug class, application, route of administration, and distribution channel. It also provides various prominent insights, such as prevalence of psoriasis and rheumatoid arthritis in key countries, patent snapshot, pipeline analysis, new product launches, key mergers & acquisitions, joint ventures, and COVID-19 impact.


Report Scope & Segmentation






















































ATTRIBUTE



DETAILS



Study Period



2019-2030



Base Year



2022



Estimated Year



2023



Forecast Period



2023-2030



Historical Period



2019-2021



Growth Rate



CAGR of 5.9% from 2023-2030



Unit



Value (USD billion)



Segmentation


 


 


 



By Drug Class



  • Anti-Tumor Necrosis Factor (TNF)

  • Interleukins Antagonists

  • Janus Kinase (JAK) Inhibitors

  • Others



By Application



  • Rheumatoid Arthritis

  • Psoriasis



  • Others



By Route of Administration



  • Oral

  • Injection


    • Intravenous

    • Subcutaneous




By Distribution Channel



  • Hospital Pharmacy

  • Retail Pharmacy

  • Online Pharmacy



By Geography



  • North America (By Drug Class, By Application, By Route of Administration, By Distribution Channel, and by Country)


    • U.S.

    • Canada


  • Europe (By Drug Class, By Application, By Route of Administration, By Distribution Channel, and by Country/Sub-region)


    • U.K.

    • Germany

    • France

    • Spain

    • Italy

    • Scandinavia

    • Rest of Europe


  • Asia Pacific (By Drug Class, By Application, By Route of Administration, By Distribution Channel, and by Country/Sub-region)


    • Japan

    • China

    • India

    • Australia

    • Southeast Asia

    • Rest of Asia Pacific


  • Latin America (By Drug Class, By Application, By Route of Administration, By Distribution Channel, and by Country/Sub-region)


    • Brazil

    • Mexico

    • Rest of Latin America


  • Middle East & Africa (By Drug Class, By Application, By Route of Administration, By Distribution Channel, and by Country/Sub-region)


    • GCC

    • South Africa

    • Rest of Middle East & Africa







Frequently Asked Questions

The value of the market size was USD 93.13 billion in 2022.

Fortune Business Insights says that the market value is projected to reach USD 139.80 billion by 2030.

The value of the market in North America was USD 59.37 billion in 2022.

The market is projected to record a CAGR of 5.9% during the forecast period of 2023-2030.

By drug class, the interleukin antagonists segment is the leading segment in this market.

Increasing prevalence of inflammatory diseases, such as rheumatoid arthritis and rise in the number of potential pipeline products are the key factors driving the market.

AbbVie Inc. and Johnson & Johnson Services, Inc. are the top players in the market.

North America is expected to hold the highest market share.

Seeking Comprehensive Intelligence on Different Markets?
Get in Touch with Our Experts

Speak to an Expert
  • 2019-2030
  • 2022
  • 2019-2021
  • 145

Personalize this Research

  • Granular Research on Specified Regions or Segments
  • Companies Profiled based on User Requirement
  • Broader Insights Pertaining to a Specific Segment or Region
  • Breaking Down Competitive Landscape as per Your Requirement
  • Other Specific Requirement on Customization
Request Customization Banner

Client Testimonials

“We are quite happy with the methodology you outlined. We really appreciate the time your team has spent on this project, and the efforts of your team to answer our questions.”

- One of the largest & renowned medical research centers based in the U.S. on a report on the U.S. NIPT Market.

“Thanks a million. The report looks great!”

- Feedback from a consultant on a report on the U.S. Beef Market.

“Thanks for the excellent report and the insights regarding the lactose market.”

- Brazil based company specializing in production of protein ingredients.

“I liked the report; would it be possible to send me the PPT version as I want to use a few slides in an internal presentation that I am preparing.”

- Global Digital Services Agency on a report on the Global Luxury Goods Market.

“This report is really well done and we really appreciate it! Again, I may have questions as we dig in deeper. Thanks again for some really good work.”

- U.S.-based biotechnology company focussing on treatment of chronic pain.

“Kudos to your team. Thank you very much for your support and agility to answer our questions.”

- Europe-based provider of solutions to automate data centre operations.

“We appreciate you and your team taking out time to share the report and data file with us, and we are grateful for the flexibility provided to modify the document as per request. This does help us in our business decision making. We would be pleased to work with you again, and hope to continue our business relationship long into the future.”

- India-based manufacturer of industrial and specialty intermediates with a strong global presence.

“I want to first congratulate you on the great work done on the Medical Platforms project. Thank you so much for all your efforts.”

- One of the largest cosmetics company in the world.

“Thank you very much. I really appreciate the work your team has done. I feel very comfortable recommending your services to some of the other startups that I’m working with, and will likely establish a good long partnership with you.”

- U.S. based startup operating in the cultivated meat market.

“We received the below report on the U.S. market from you. We were very satisfied with the report.”

- Global hearing aids manufacturer.

“I just finished my first pass-through of the report. Great work! Thank you!”

- U.S. based solar racking solutions provider.

“Thanks again for the great work on our last partnership. We are ramping up a new project to understand the imaging and imaging service and distribution market in the U.S.”

- World’s leading advisory firm.

“We feel positive about the results. Based on the presented results, we will do strategic review of this new information and might commission a detailed study on some of the modules included in the report after end of the year. Overall we are very satisfied and please pass on the praise to the team. Thank you for the co-operation!”

- Germany based machine construction company.

“Thank you very much for the very good report. I have another requirement on cutting tools, paper crafts and decorative items.”

- Japanese manufacturing company of stationery products.

“We are happy with the professionalism of your in-house research team as well as the quality of your research reports. Looking forward to work together on similar projects”

- One of the Leading Food Companies in Germany

“We appreciate the teamwork and efficiency for such an exhaustive and comprehensive report. The data offered to us was exactly what we were looking for. Thank you!”

- Intuitive Surgical

“I recommend Fortune Business Insights for their honesty and flexibility. Not only that they were very responsive and dealt with all my questions very quickly but they also responded honestly and flexibly to the detailed requests from us in preparing the research report. We value them as a research company worthy of building long-term relationships.”

- Major Food Company in Japan

“Well done Fortune Business Insights! The report covered all the points and was very detailed. Looking forward to work together in the future”

- Ziering Medical

“It has been a delightful experience working with you guys. Thank you Fortune Business Insights for your efforts and prompt response”

- Major Manufacturer of Precision Machine Parts in India

“I had a great experience working with Fortune Business Insights. The report was very accurate and as per my requirements. Very satisfied with the overall report as it has helped me to build strategies for my business”

- Hewlett-Packard

“This is regarding the recent report I bought from Fortune Business insights. Remarkable job and great efforts by your research team. I would also like to thank the back end team for offering a continuous support and stitching together a report that is so comprehensive and exhaustive”

- Global Management Consulting Firm

“Please pass on our sincere thanks to the whole team at Fortune Business Insights. This is a very good piece of work and will be very helpful to us going forward. We know where we will be getting business intelligence from in the future.”

- UK-based Start-up in the Medical Devices Sector

“Thank you for sending the market report and data. It looks quite comprehensive and the data is exactly what I was looking for. I appreciate the timeliness and responsiveness of you and your team.”

- One of the Largest Companies in the Defence Industry
We use cookies to enhance your experience. By continuing to visit this site you agree to our use of cookies . Privacy.
X