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Blood Group Typing Market Size, Share & COVID-19 Impact Analysis, By Product (Instruments and Reagents & Kits), By Test Type (ABO Tests, Antigen Typing, Antibody Screening, Cross-matching Tests, and HLA Typing), By Technique (Serology Tests and Molecular Tests), By End-user (Hospital-based Laboratories and Independent Laboratories & Blood Banks), and Regional Forecast, 2022-2029

Region : Global | Format: PDF | Report ID: FBI101767



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The global blood group typing market size was valued at USD 1.62 billion in 2021. The market is projected to grow from USD 1.96 billion in 2022 to USD 3.71 billion by 2029, exhibiting a CAGR of 9.5% during the forecast period. The global COVID-19 pandemic has been unprecedented and staggering, with blood group typing experiencing lower-than-anticipated demand across all regions compared to pre-pandemic levels. Based on our analysis, the global market exhibited a decline of 3.8% in 2020 as compared to 2019.

Blood group typing is a test to determine a person’s blood type. The surging demand for blood transfusions and organ transplantations is a foremost factor propelling the market growth. The World Health Organization (WHO) states that an increase of 10.7 million blood donations has occurred in terms of voluntary blood donations from 2008-2018. The increase in donations over the years signifies that the number of blood group typing procedures has also increased. Furthermore, due to rise in the incidence of accidents, cases of trauma and injuries have risen enormously. It is also stated that in a trauma setting, 6 out of 10 deaths occur due to excessive bleeding in the first 3 hours of the injury. Therefore, in such cases, massive transfusion as a treatment is performed. Thus, the growing number of trauma and accident cases globally drives the growth of the market.

Additionally, favorable strategic initiatives by various key players and public-private partnerships also facilitate innovation and advances in the market. Also, some recent developments in automated blood typing technologies are expected to be instrumental in impelling the blood group typing market growth. For instance, in July 2020, Japan's Tokyo University of Science team of scientists developed a lab-on-a-chip device that can tell the blood type within five minutes and allows medical staff to read the results through simple visual inspections. Such R&D initiatives are contributing to the expansion of the global market during the forecast period.


How has the COVID-19 Pandemic Impacted the Market?

The COVID-19 pandemic has resulted in a decline in the number of blood transfusions and donations, manufacturing and supply chain issues, and a decrease in the number of visits to healthcare facilities leading to reduced usage of these diagnostic products. This hindered the demand for these products on a global level. For instance, according to the French Blood Establishment (EFS), in September 2020, during the peak of the pandemic, blood donations in France were driven to historic lows as the pandemic restrictions led to the cancellation of mobile blood collections at workplaces and universities, which accounted for an estimated 80.0% of the French blood donations.

In 2020, the pandemic impacted the sales of blood group typing across the globe. Some prominent market players reported considerable sales decline in their annual revenues. For instance, critical companies in the global market, such as Bio Rad Laboratories, Inc., witnessed a decrease of 7.6% in their clinical diagnostics segments, including ID-system, and microplates during FY 2020 compared to the same period in 2019. However, the company witnessed an increase in sales of its clinical diagnostics segment by 16.1% in FY 2021. However, robust adoption of automated technologies coupled with improved patient visits is anticipated to return the market to its pre-pandemic growth levels in the forecast period.


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How does the Adoption of Automated Blood Typing Technologies Determine Market Growth Trajectory?

The global market has recently witnessed an increased focus on developing automated blood typing technologies. Automated blood typing technologies, such as Polymerase Chain Reaction (PCR) based and microarray techniques, have improved transfusion diagnostics' speed, standardization, and safety.

Automatic blood typing has several advantages over manual typing in terms of cost, efficiency, and errors. An additional benefit of these systems is it helps to overcome the shortage of healthcare personnel and less-experienced staff at transfusion testing services institutions. Therefore, many vital and emerging players are engaged in the introduction of technologies in this market. For instance, in July 2020, a team of scientists from Tokyo University of Science, Japan, developed a lab-on-a-chip device that can tell the blood type within five minutes and allows medical staff to read the results through simple visual inspections. Such rising trends are expected to contribute intensely to the market growth.


How Does the Increase in the Number of Blood Donations Elevate Market Growth? 

Over the years, there has been a rise in the number of blood donations collected globally. Due to an increase in voluntary blood donations, the demand for blood group recognition and cross-matching procedures for transfusion has increased. As per the European Blood Alliance (EBA) article (2019-2022), the National Health Service Blood and Transplant (NHSBT) collects around 1.5 million voluntary blood donations, which are processed by the authority before being delivered to hospitals and the patients who need them. NHSBT relies on 1.3 million registered donors as it provides a safe and reliable supply of blood components, diagnostic services, and stem cell services to hospitals in England. The increase in the number of these procedures due to the surge in blood donations over the forecast period is set to drive the market growth.

Furthermore, there has been an upsurge in the demand for blood and blood components across all regions for various medical and surgical applications. Also, the rising number of government initiatives to increase awareness regarding voluntary blood donations contributes to the increasing number of donations among people in the forecast period. According to an article published by Wausau Pilot & Review in June 2022, every 2 seconds, there is a need for blood or platelets in the U.S. The strong demand for these procedures is leading to the market growth.   

How are the Rising Transplantation Procedures Surging the Demand for HLA Typing?

One of the most critical drivers boosting the global market is the increasing number of transplantation procedures across the globe. The increase in the number of transplants leads to the rising number of Human Leukocyte Antigen (HLA) typing tests, contributing to market growth. As per data published by the Organ Procurement and Transplantation Network (OPTN), in 2021, 41,354 organ transplantations were done in the U.S., with an increase of 5.9% over 2020.

Furthermore, the HLA typing method is essential during renal transplantation, as recognizing a foreign HLA by the T Lymphocytes triggers the immune response. The activated T Lymphocytes initiate a series of mediators, which leads the immune system against the allograft. Therefore, the rise in kidney transplants also leads to an increase in the number of HLA typing tests. Similarly, according to the data published by International Registry on Organ Donation and Transplantation (IRODaT), the number of kidney transplants performed by living donors in Spain in 2021 was 2,627. Therefore, according to global statistics, there has been a growth in the number of organ transplants, which positively contributes to the rise in the number of HLA typing procedures, eventually boosting the market growth.


How does the Lack of Infrastructure & Trained Personnel for these Procedures in Emerging Nations Hinder Market Growth?

Despite the intense demand for blood donation and transfusion procedures among the patient population, a substantial hindrance to market growth is the lack of infrastructure for blood group typing, especially in emerging countries. For instance, in 2019 an article published by John Wiley & Sons, Inc., in Nigeria, the National Blood Transfusion Service (NBTS) was inaugurated to promote sustainable, safe blood availability to individuals. Still, in Ivory Coast, the NBTS failed to meet its mission as it lacked blood collection equipment and poor donor turnout. This same setback has also been seen in Mali and Nigeria, where the lack of infrastructure, trained personnel, and inadequate funding undermine the availability of safe blood services.

Some other contributory factors include long distances between centralized services and hospitals, infrastructure failures such as constant electricity supply, and lack of political support as hindrances for blood donation and transfusion procedures. Also, emerging nations lag in reimbursement policies for these procedures. This increases cost barriers leading to lowered testing rates. Hence, as mentioned above, these factors can restrict market growth during the forecast period.


By Product Analysis

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Reagents & Kits Segment to Emerge Dominant due to Rising Procedural Volume

The global market can be segmented based on product into instruments and reagents & kits. The reagents & kits segment dominated the market as these products are extensively used for these procedures. The mounting number of blood donations and transfusions is one of the primary reasons for segmental expansion. The instruments segment is projected to witness positive growth prospects during the forecast period. The rising usage of advanced instruments for these procedures and technological advancements and strategic initiatives is set to augment segment growth. In July 2021, Thermo Fisher Scientific Inc. and Ortho Clinical Diagnostics partnered for providing Thermo’s LabLink xL Quality Assurance Software and MAS Quality Controls via Ortho's VITROS QC Solutions to VITROS System customers across the globe.

By Test Type Analysis

Antibody Screening to Record Appreciable Growth Due to Increased Product Usage 

On the basis of test type, the global market can be segmented into ABO tests, antigen typing, antibody screening, cross-matching tests, and HLA typing. The antibody screening segment dominated the market due to increased blood transfusions, rising prevalence of chronic diseases, and prenatal testing. Pregnant patients require various screening tests during pregnancy, including blood group and antibody screening. Thus, increase in prenatal testing is augmenting the growth of the segment.

The ABO tests segment held the second leading position in 2021. The increasing usage of ABO blood typing to identify and match organ and tissue transplantation procedures is augmenting segmental growth. The antigen typing segment is anticipated to account for the third-largest market share due to the rising usage of these tests for patients requiring long-term transfusion therapy such as sickle cell disease to obtain phenotypically compatible units.

In addition, the cross-matching tests and HLA typing segments are projected to grow with a significant CAGR as they are utilized for the identification and matching of organ and tissue transplantation procedures in the region.

By Technique Analysis

Serology Tests to Register Rising Demand due to New Approvals

The market is segmented based on technique into serology tests and molecular tests. The serology tests segment dominated the global blood group typing market share due to rising initiatives for voluntary blood donations and new product launches. Serology tests are one of the traditional methods of this market and can be used for the laboratory or research process. Also, they are easy to use and readily available, which creates the demand for these products in the market. In July 2021, Ortho Clinical Diagnostics (now QuidelOrtho Corporation) announced that VITROS Immunodiagnostic Products IL-6 Reagent Pack is available in EU countries, the U.K., and several APAC and LATAM countries.

The molecular tests segment is projected to grow significantly owing to the rising popularity of molecular testing. The robust efficacy of molecular tests in detecting is the prominent factor contributing to the expansion of the segment.

By End-user Analysis

Independent Laboratories & Blood Banks Segment to Record Appreciable Growth Due to Rising Setup

Based on end-user, the market is segmented into hospital-based laboratories and independent laboratories & blood banks. The independent laboratories & blood banks segment dominates the market and is expected to grow due to an upsurge in the number of independent laboratories & blood banks, including in emerging nations. According to a news article published by the New Indian Express in March 2020, there were nearly 110,000 medical laboratories in India. The presence of laboratories in key countries is anticipated to drive the segment’s growth in the forecast period.

In terms of end-user, the hospital-based laboratories segment accounts for the second largest market share. The rising number of hospitals in major countries and favorable reimbursement policies will contribute to segmental expansion during the forecast period.


North America Blood Group Typing Market Size, 2021 (USD Billion)

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Based on region, the global market is studied across North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.

The market size in North America was valued at USD 0.60 billion in 2021 and is anticipated to lead the global market during the forecast period. The region dominates the market due to the significant demand for blood transfusions, higher adoption of automated blood typing instruments, and favorable reimbursement policies for these procedures. Furthermore, the regulatory approvals for advanced products is driving the market growth in North America. For instance, in March 2021, Grifols, S.A. installed the DG Reader Net semi-automated analyzer in North America. It is used for compatibility testing of pre-transfusion blood types.

The Europe region accounted for the second-largest market share in 2021. The market will be primarily driven by the increased number of these procedures and rising awareness amongst individuals regarding blood donations. According to an article published by the National Health Service (NHS) in June 2021, the U.K. Health Ministry has prepared a new strategy and set out the vision for the U.K. to be a world leader in terms of organ donation and transplantation. The Asia Pacific market is expected to upsurge remarkably due to increasing R&D initiatives to launch advanced blood group typing technologies. Such R&D initiatives are anticipated to give rise to novel product launches in Japan. The market in Latin America has been growing due to increasing awareness regarding blood and organ donations in Mexico and Brazil. The rising blood collection systems in Latin America effectively contributes to market growth in the forecast period. For instance, in November 2019, Grifols, S.A. started production at a new blood-collection systems plant in Campo Largo, Brazil. The new plant enabled key companies such as Grifols to expand their presence in Latin America.

The Middle East & Africa region is anticipated to witness growth prospects over the forecast period due to increasing awareness regarding blood donations and rise in the number of blood transfusions in hospital trauma centers.


Advanced Product Portfolio and Strong Sales Enabled QuidelOrtho Corporation to Gain Top Market Position in 2021

The competitive landscape reflects a semi-consolidated nature which includes the presence of several regional and international blood group typing players operating in the global market. QuidelOrtho Corporation accounted for a significant share of the global market in 2021. Consistent product approvals and launches, coupled with robust distribution agreements have enabled QuidelOrtho Corporation to be considered a market pioneer. For instance, in September 2021, QuidelOrtho Corporation launched New Immediate Spin Crossmatch (ISXM) for ORTHO VISION MAX and ORTHO VISION Analyzers for aiding in incompatibility detection between donors and recipients in blood transfusions.

At the same time, Grifols S.A. and Bio-Rad Laboratories, Inc. held prominent shares in the global market due to strategic initiatives and multiple regulatory approvals from government organizations. In March 2021, Bio-Rad Laboratories, Inc. entered into a partnership with F. Hoffmann-La Roche Ltd. Under this partnership, Bio-Rad Laboratories provided the customers of F. Hoffmann-La Roche Ltd. access to InteliQ products, Unity QC data management solutions, and customer training and support services. Other key players in the market are Quotient Limited, Agena Bioscience, Inc., and CareDx Inc. They are slowly gaining a robust market share due to strategic initiatives, including collaborations and distribution agreements to improve their market position over the forecast period.



  • March 2022: Quotient Limited received the Conformité Européenne (CE) Mark for its MosaiQ Extended Immunohematology (IH) microarray.

  • July 2022: Quotient Limited signed an agreement with InfYnity Biomarkers to expand MosaiQ's infectious disease menu, including blood screening tests.

  • April 2021: Quotient Limited announced positive results from MosaiQ Multiplex Molecular Disease Screening (MDS) microarray study and the company's progress regarding MosaiQ expanded Immunohematology (IH) microarray was updated.

  • October 2020: Calibre Scientific acquired Lorne Laboratories, which manufactures blood grouping reagents and diagnostic test kits for medical procedures.

  • July 2020: Beckman Coulter, Inc. received the 510(k) clearance from the U.S. Food and Drug Administration (FDA) for the iPK7400 automated microplate system and reagents. Thus, it will be marketed in countries across Europe, Canada, and the U.S.


An Infographic Representation of Blood Group Typing Market

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The research report comprises a detailed global blood group typing market analysis. The market is segmented by product, test type, technique, and end-user. The report focuses on crucial aspects such as market dynamics, key industry developments including mergers, acquisitions, and partnerships, technological advancements in blood group typing, number of blood donations and transfusions, prominent market players, and the COVID-19 pandemic impact on the global market. In addition, the global market analysis includes insights into the market trends and highlights pricing and other operating company profiles in HLA typing products that have contributed to the market growth in recent years.




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Value (USD Billion)


By Product, Test Type, Technique, End-user, and Geography

By Product

  • Instruments

  • Reagents & Kits

By Test Type

  • ABO Tests

  • Antigen Typing

  • Antibody Screening

  • Cross-matching Tests

  • HLA Typing

By Technique

  • Serology Tests

  • Molecular Tests

By End-user

  • Hospital-based Laboratories

  • Independent Laboratories & Blood Banks

By  Region

  • North America (By Product, By Test Type, By Technique, By End-user, and By Country)

    • U.S.

    • Canada

  • Europe (By Product, By Test Type, By Technique, By End-user, and By Country/Sub-Region)

    • Germany

    • U.K.

    • France

    • Italy

    • Spain

    • Scandinavia

    • Rest of Europe

  • Asia Pacific (By Product, By Test Type, By Technique, By End-user, and By Country/Sub-Region)

    • China

    • Japan

    • India

    • Australia

    • Southeast Asia

    • Rest of Asia Pacific

  • Latin America (By Product, By Test Type, By Technique, By End-user, and By Country/Sub-Region)

    • Brazil

    • Mexico

    • Rest of Latin America

  • Middle East & Africa (By Product, By Test Type, By Technique, By End-user, and By Country/Sub-Region)

    • GCC

    • South Africa

    • Rest of Middle East & Africa

Frequently Asked Questions

Fortune Business Insights says that the global market size was USD 1.62 billion in 2021 and is expected to reach USD 3.71 billion by 2029.

The market will exhibit steady growth at a CAGR of 9.5% during the forecast period (2022-2029).

The reagents & kits segment is expected to be the leading segment in this market during the forecast period.

The increase in the number of blood donations and transplantation procedures and the rise in trauma and accident cases are driving the market growth.

Grifols S.A., Quotient Limited, Bio-Rad Laboratories, Inc., QuidelOrtho Corporation, and CareDx Inc. are some major global market players.

North America dominated the market in 2021.

Increase in these procedures, rising government initiatives to increase blood donation awareness, and technological advancements across the globe are expected to drive the adoption of these products.

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