"Designing Growth Strategies is in our DNA"
The global sickle cell disease treatment market size was valued at USD 2.25 billion in 2022. The market is projected to grow from USD 2.73 billion in 2023 to USD 9.84 billion by 2030, exhibiting a CAGR of 20.1% during the forecast period.
Sickle Cell Disease (SCD) is an inherited disorder causing diseases, such as hemoglobin sickle cell disease, hemoglobin SS disease, sickle cell anemia, and others causing deformation of red blood cells. This leads to early death of cells, causing blood shortage, and also inhibits blood flow, causing blockage. The treatment procedure includes blood transfusions, medication, and bone marrow transplants.
The global sickle cell disease treatment market growth is attributed to the increasing prevalence of SCD, rising awareness regarding the disease, and increasing focus of the key players on launching new effective drugs for sickle cell disease treatment.
Decreased Bone Marrow Donations and Scarcity of Donors Hampered Market Growth amid the Pandemic
The outbreak of COVID-19 had no impact on the pharmacotherapy segment of the market due to the branded pharmaceutical treatment medication commercialization from 2019-2020.
However, the blood transfusion and bone marrow transplant segments experienced a decline in growth in 2020 compared to the prior year due to the reallotment of healthcare solutions for COVID-19 treatment. Furthermore, since the number of people opting for sickle cell disease treatment was reduced, the market was affected negatively.
Furthermore, the market experienced significant growth post-COVID-19 outbreak. This was due to the increased sales of sickle cell disease treatment drugs.
Increasing Gene Therapy Adoption Bolstered the Development of Effective SCD Treatments
Gene therapy has emerged as the ultimate cure for various chronic diseases. In the case of hereditary diseases, gene therapy is a revolution that targets the root cause of a disease. With increasing research on the correction of genetic mutation for the treatment of the disease, market players have shifted their R&D focus toward gene therapy.
Similarly, CRISPR Therapeutics and Vertex Pharmaceuticals have been conducting clinical trials on CRISPR-Cas9 gene-edited therapy CTX001. It is currently in phase 3 clinical and is estimated to be completed in October 2024. Positive clinical studies on CTX001 suggest that the pipeline candidate can become a blockbuster drug when it is launched in the market. Due to this factor, the global market is expected to witness growth in the coming years.
Request a Free sample to learn more about this report.
Increasing Prevalence along with High Severity Related to the Disease to Surge the Demand for Effective Treatment Procedures
Globally, millions of people are affected by sickle cell disease. The growing prevalence of sickle cell disease is driving market expansion.
Youngsters and adults with sickle cell disease frequently experience the extreme consequence known as Vaso-occlusive Crisis (VOC). The increasing need for emergency medical care among patients due to sudden acute discomfort instances is boosting market expansion.
Increasing emphasis on the introduction of drugs to decrease the acuteness of these illnesses by leading market players is supporting market expansion.
The increasing prevalence of SCD and the efficacy of the products for the disease treatment in reducing the chances of VOCs are increasing its adoption among patients.
Advent of Novel Treatment Solutions to Contribute to Market Growth
Prior, only bone marrow transplantation and blood transfusion were included in SCD management. The growing incidence of sickle cell disease and increasing awareness about it boosted the adoption of efficient treatment procedures.
Major players increased their focus on the launch of new products for the treatment of this disease and to meet the demands of the patients.
After the launch of Endari, a few more companies emerged in the market with new product launches, including Oxbryta (Global Blood Therapeutics), Adakveo (Novartis), Zynteglo (bluebird bio, Inc.), and PYRUKYND (Agios Pharmaceuticals, Inc.).
Additionally, by offering quick product approvals, the FDA and European Medicines Agency (EMA) are also playing a major role. The FDA grants fast approval to medications for severe illnesses to address an unmet medical need.
The growing prevalence of SCD and the expected new drug introductions are anticipated to foster market growth over the forecast period.
Lack of SCD Treatment Options in Emerging Countries to Limit Market Growth
The pharmacotherapy of sickle cell disease treatment consists of hydroxyurea and a few branded drugs. Hydroxyurea is considered the first line of disease treatment and is recommended by many healthcare professionals. However, the lack of availability of treatment options in the developing countries across the globe stands out as a restraining factor.
Moreover, blood transfusions for SCD management are also dependent on donor availability. There are chances of inappropriate screening, leading to increased blood transfusion-transmitted infections, even though donors are accessible.
Public and private funding in African countries is insufficient to improve the healthcare facilities and care required by patients suffering from the disease.
Furthermore, combined with the lack of awareness about the disease among the population in emerging economies can limit the global market growth during the forecast period.
Blood Transfusion Segment Led Backed by its Efficiency in Treatment Modality for Stroke Management
The market is divided into blood transfusion, bone marrow transplant, and pharmacotherapy, in terms of treatment modality. The pharmacotherapy segment is segregated into branded products and hydroxyurea.
The blood transfusion segment generated the highest revenue in 2022 and is expected to grow at a stagnant CAGR during the forecast period. Blood transfusion is the most efficient treatment method to manage strokes, which is one of the severe symptoms of SCD. The increasing number of episodes of strokes among SCD patients has increased the blood transfusion treatment demand. This factor is responsible for the segment’s dominance.
Furthermore, the pharmacotherapy segment is expected to grow at the fastest CAGR during the forecast period. The high growth rate of the segment is due to the launch of new branded pharmacotherapy drugs and increasing government initiatives on early launches of these drugs. Moreover, limited treatment options currently available in the market are also responsible for the segment’s growth in the forecast period. The government in countries, such as the U.S., India, and others supports research activities for sickle cell disease treatment through funding and designations such as orphan drugs, fast track, and priority review, among others. These factors are expected to accelerate the introduction of new labeled pharmacotherapy drugs and provide significant momentum to the pharmacotherapy segment.
To know how our report can help streamline your business, Speak to Analyst
Hospitals Segment Dominated Attributable to Rising Prevalence of Patients Visiting Hospitals
Based on end-user, the market is segmented into hospitals, specialty clinics, and others.
The hospitals segment held significant global sickle cell disease treatment market share in 2022. The large share of the segment is attributed to the increasing prevalence of SCD and the rising number of hospital admissions for sickle cell disease treatment.
The specialty clinics segment is estimated to grow at a significant CAGR during the forecast period. This segment’s growth is attributable to the increasing number of specialty clinics providing sickle cell disease treatment and care.
The U.S. market generated a revenue of USD 1.44 billion in 2022. The dominance of the market in the country is attributed to better access to SCD treatment, potential pipeline candidates, strong government support, and rising collaborations to improve the treatment of the disease.
Europe accounted for a significant market share in 2022 and is projected to witness a considerable growth during the forecast period. The market growth in Europe is attributed to favorable reimbursement policies, increasing prevalence of the disease, and increasing market players’ emphasis on the expansion of their offerings in the region.
The market in the rest of the world is expected to expand at a significant CAGR in the projected years. Market expansion in the region is driven by the highest SCD incidence in the Middle East & Africa, the Mediterranean regions, and South America and rising disposable income. Moreover, the increasing awareness about SCD and the strong pipeline of branded drugs are also expected to fuel the market growth in the region.
Companies with Strong Sickle Cell Disease Treatment Sales to Dominate the Competition
Global Blood Therapeutics Inc. (Pfizer Inc.), Novartis AG, and Emmaus Medical, Inc. are the prominent players in the market and captured a considerable global market share in 2022.
Global Blood Therapeutics Inc. (Pfizer Inc.) accounted for a significant market share in 2022 due to the company’s strong sales from Oxbryta for SCD treatment.
Similarly, Novartis AG held a considerable share of the market in 2022 due to increasing focus on partnerships with several government organizations. This partnership may allow the company to address the unmet needs of the patient population. Moreover, the company’s emphasis on the expansion of the availability of its product globally is also responsible for its significant position in the market.
Furthermore, the blood transfusion segment also generated significant revenues due to increasing SCD complications, such as stroke, which can be prevented through blood transfusion therapy.
An Infographic Representation of Sickle Cell Disease Treatment Market
To get information on various segments, share your queries with us
The market research report provides a detailed competitive landscape. It includes the prevalence of sickle cell disease and key industry developments such as partnerships, mergers, and acquisitions. Additionally, it focuses on key points such as new product launches in the market. Furthermore, the report covers regional analysis of different segments and company profiles of key sickle cell disease treatment players, including business overview, financial data, and SWOT analysis for each company. Moreover, the report includes market trends and the impact of COVID-19 on the market. The report consists of quantitative and qualitative insights contributing to the market's growth.
CAGR of 20.1% from 2023-2030
Value (USD Billion)
By Treatment Modality, End-user, and Geography
By Treatment Modality
Fortune Business Insights says that the global market stood at USD 2.25 billion in 2022 and is projected to reach USD 9.84 billion by 2030.
The market is expected to exhibit a CAGR of 20.1% during the forecast period (2023-2030).
The pharmacotherapy segment is set to lead the market by treatment modality.
The key factors driving the market are the wave of innovation in SCD therapeutics, increasing prevalence of SCD, and approval of advanced pharmacotherapy drugs to manage the disease.
Global Blood Therapeutics Inc. (Pfizer Inc.), Novartis AG, and Emmaus Medical, Inc. are the top players in the market.
“This report is really well done and we really appreciate it! Again, I may have questions as we dig in deeper. Thanks again for some really good work.”- U.S.-based biotechnology company focussing on treatment of chronic pain.
“Kudos to your team. Thank you very much for your support and agility to answer our questions.”- Europe-based provider of solutions to automate data centre operations.
“We appreciate you and your team taking out time to share the report and data file with us, and we are grateful for the flexibility provided to modify the document as per request. This does help us in our business decision making. We would be pleased to work with you again, and hope to continue our business relationship long into the future.”- India-based manufacturer of industrial and specialty intermediates with a strong global presence.
“I want to first congratulate you on the great work done on the Medical Platforms project. Thank you so much for all your efforts.”- One of the largest cosmetics company in the world.
“Thank you very much. I really appreciate the work your team has done. I feel very comfortable recommending your services to some of the other startups that I’m working with, and will likely establish a good long partnership with you.”- U.S. based startup operating in the cultivated meat market.
“We received the below report on the U.S. market from you. We were very satisfied with the report.”- UGlobal hearing aids manufacturer.
“I just finished my first pass-through of the report. Great work! Thank you!”- U.S. based solar racking solutions provider.
“Thanks again for the great work on our last partnership. We are ramping up a new project to understand the imaging and imaging service and distribution market in the U.S.”- World’s leading advisory firm.
“We feel positive about the results. Based on the presented results, we will do strategic review of this new information and might commission a detailed study on some of the modules included in the report after end of the year. Overall we are very satisfied and please pass on the praise to the team. Thank you for the co-operation!”- Germany based machine construction company.
“Thank you very much for the very good report. I have another requirement on cutting tools, paper crafts and decorative items.”- Japanese manufacturing company of stationery products.
“We are happy with the professionalism of your in-house research team as well as the quality of your research reports. Looking forward to work together on similar projects”- One of the Leading Food Companies in Germany
“We appreciate the teamwork and efficiency for such an exhaustive and comprehensive report. The data offered to us was exactly what we were looking for. Thank you!”- Intuitive Surgical
“I recommend Fortune Business Insights for their honesty and flexibility. Not only that they were very responsive and dealt with all my questions very quickly but they also responded honestly and flexibly to the detailed requests from us in preparing the research report. We value them as a research company worthy of building long-term relationships.”- Major Food Company in Japan
“Well done Fortune Business Insights! The report covered all the points and was very detailed. Looking forward to work together in the future”- Ziering Medical
“It has been a delightful experience working with you guys. Thank you Fortune Business Insights for your efforts and prompt response”- Major Manufacturer of Precision Machine Parts in India
“I had a great experience working with Fortune Business Insights. The report was very accurate and as per my requirements. Very satisfied with the overall report as it has helped me to build strategies for my business”- Hewlett-Packard
“This is regarding the recent report I bought from Fortune Business insights. Remarkable job and great efforts by your research team. I would also like to thank the back end team for offering a continuous support and stitching together a report that is so comprehensive and exhaustive”- Global Management Consulting Firm
“Please pass on our sincere thanks to the whole team at Fortune Business Insights. This is a very good piece of work and will be very helpful to us going forward. We know where we will be getting business intelligence from in the future.”- UK-based Start-up in the Medical Devices Sector
“Thank you for sending the market report and data. It looks quite comprehensive and the data is exactly what I was looking for. I appreciate the timeliness and responsiveness of you and your team.”- One of the Largest Companies in the Defence Industry