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The joint pain injections market was USD 4.79 billion in 2022 and is projected to grow from USD 5.16 billion in 2023 to USD 9.20 billion by 2030, exhibiting a CAGR of 8.6%. The growing number of treatments is attributed to the favorable reimbursement policies in developed countries.
The increasing prevalence of osteoarthritis, rheumatoid arthritis, and musculoskeletal disorders in the general population is responsible for the increasing number of patients suffering from joint pain and related complications. The rising awareness among the patient population regarding the condition and available treatment options are some of the major factors responsible for the rising demand for intra-articular injections for the treatment of joint pain in developed and emerging countries. Additionally, the growing awareness of the benefits of intra-articular injections in treating joint pain is responsible for the increasing demand for joint pain injections.
Therefore, these factors along with robust efforts of the key market players to develop and introduce novel therapies for the treatment of osteoarthritis are anticipated to propel the demand and adoption of joint pain injections.
Deferral of Elective Procedures During COVID-19 Hampered the Market Growth
The emergence of COVID-19 significantly hampered the demand for joint pain injections worldwide. The key players operating in the market reported a decline in their revenues during the period due to significant decrease in product sales.
The significant decline in the revenues for the pain injections industry was attributed to the reduced number of patient visits for treatment, declined number of elective procedures, and reallocation of healthcare resources for COVID-19 management.
Moreover, the increased adoption of alternative treatment options, such as oral drugs, and others, during the pandemic is another factor that contributed to the decline of the market.
There was a disruption in business activities, such as manufacturing and logistics, due lockdown restrictions in major markets for pain injections. Therefore, a significant decline in growth was reported by major players in 2020. For instance, Bioventus Inc. recorded a 6% decline in revenues from OA joint pain treatment and joint preservation business segment in 2020 compared to 2019. The decline in revenues from joint pain injections was attributed to a decrease in the number of procedures performed in 2020.
However, with the ease of lockdown restrictions in 2021, the diagnosis rate of the condition among the population increased, and procedures and treatment services by healthcare providers globally were resumed. The market players witnessed growth in revenue as compared to 2020. For instance, Bioventus witnessed a growth of around 29.5% in its pain treatment segment in 2021 as compared to the previous financial year.
Thus, with the rising prevalence of osteoarthritis and other musculoskeletal conditions among the population globally and the rising number of product approvals and launches, the global market is expected to grow in the near future.
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Rising Preference for Minimally Invasive Joint Pain Procedures among Healthcare Providers
The growing prevalence of osteoarthritis and other musculoskeletal disorders among the population especially in the geriatric population is leading to rising demand for joint pain injections. The rising geriatric population is another factor fueling the increasing demand for joint pain injections globally.
The increasing benefits of these injections such as their quick and painless process, minimally-invasive nature, rapid adsorption of the drug, longer relief period for patients, and others are resulting in increasing adoption of these injections among the healthcare provider.
Also, major players operating in the market are involved in the development of innovative treatment solutions such as platelet-rich plasma injections and plasma matrix therapy. Additionally, ongoing research activities highlight benefits associated with novel treatments, which support the adoption of innovative products.
Additionally, the drugs currently available in the market such as hydrocortisone injections are generally administered in three or five injections. This factor is responsible for higher treatment costs and lack of adherence to the treatment. Therefore, key players operating in the market introduce single injection therapy. Single injection therapy is a more effective and saving option for treating joint pain. Also, according to RxList Inc., Monovisc, which is a hyaluronic acid visco-supplement single injection used for the therapy of joint pain associated with osteoarthritis, is equivalent to three injection therapy of Orthovisc by Anika Therapeutics, Inc.
Therefore, the introduction of innovative products in the market is responsible for increasing the shift of preference toward injections for joint pain management.
Growing Prevalence of Osteoarthritis and Obesity in General Population to Surge Product Demand
The rapid rise in the prevalence of osteoarthritis and other musculoskeletal disorders globally is the result of several factors, including the continuous rise in the geriatric population, and the shift toward the adoption of a sedentary lifestyle, in both developed and emerging countries worldwide.
Thus, the presence of a large patient pool suffering from osteoarthritis and the growing awareness for early diagnosis & treatment are responsible for increasing demand for pain treatment products, including joint pain injections.
Increasing per capita expenditure on healthcare in developed countries and new product launches by market players bolster the demand for intra-articular injections in the global market.
Rising R&D Activities Among Major Players & Pipeline Candidates to Fuel the Product Demand
The rising prevalence of arthritis and other musculoskeletal disorders and increasing diagnosis rate among the general population are expected to fuel the demand for joint pain injections in the market.
The increasing R&D activities among the key players operating in the market to strengthen their product portfolio and develop novel products to cater to the rising demand among the patient population in the market is anticipated to augment the adoption of these products in the market.
The growing number of pipeline candidates by major players in the market is another crucial factor expected to propel the market growth.
All the factors mentioned above along with rising partnerships and collaborations among major players and startups to develop and introduce novel products and therapies for various musculoskeletal disorders are projected to drive market growth.
High Cost of Injections and Lack of Reimbursement Policies to Limit Adoption in Emerging Countries
The rising prevalence of musculoskeletal disease and the surge in demand for effective treatment are propelling the demand for these products. However, the high costs of these injections and stringent regulations for product approvals are some of the major factors estimated to limit the joint pain injections market growth.
Also, rising awareness about cost-effective alternatives for pain management among the patient population is another factor anticipated to hinder the demand for these injections in the market.
Limited reimbursement policies for these products in developing countries are anticipated to limit the adoption of these injections among the patient population. Moreover, lack of awareness about these products in developing countries is accountable for the lower adoption of intra-articular injections in the treatment of joint pain.
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Clinically Proven Benefits Increases Preference toward HA-based Injections Globally
Based on product, the market is segmented into corticosteroid injections, hyaluronic acid (HA) injections, platelet rich plasma injections, and others.
The HA injections segment accounted for the largest global joint pain injections market share in 2022. The growing number of patients with osteoarthritis pain and the rising awareness about clinical benefits offered by HA injections are responsible for the growing adoption of these products among osteoarthritis patients with moderate to severe pain.
Additionally, the rising number of product approvals for HA injections, also referred to as viscosupplements/gel injections are anticipated to further augment the segment's growth in future.
On the other hand, the corticosteroid injections segment held the second largest market share. These are usually the first line of treatment for osteoarthritis preferred by clinicians. The increasing prevalence and diagnosis rate of these conditions among the general population globally is one of the major factors contributing to the growth of the segment.
The platelet rich plasma injections segment is anticipated to register a higher CAGR than other segments due to the increasing number of clinical trials to establish the efficiency of platelet-rich plasma therapy for pain management among osteoarthritis patients and their projected approvals.
Higher Prevalence of Joint Pain in Knee is Responsible for Higher Share of the Segment
On the basis of joint type, the market is segmented into knee, hip, hand & wrist, and others.
The knee segment accounted for the largest market share in 2022 and is expected to grow at a significant CAGR during the forecast period. The increasing demand for intra-articular injections for the management of knee pain is attributed to the rising cases of knee osteoarthritis.
Moreover, the knee segment is expected to dominate the global market share owing to factors such as strong product portfolio offered by key players for the treatment of pain associated with knee osteoarthritis and the growing number of product approvals for knee osteoarthritis.
The hand & wrist segment accounted for the second-largest share of the market in 2022. The growth of this segment is attributed to the increasing incidence of hip osteoarthritis among the global population coupled with the growing number of clinical trials for this indication.
Hip segment is expected to grow at a considerable CAGR during the forecast period. The growth of the segment is attributed to various factors such as increasing prevalence of the condition among the general population, increasing diagnosis rate, and rising number of patients taking treatment for the condition.
The others segment is expected to grow owing to the rising prevalence of other joint types such as spine and foot & ankle, among others. The rising adoption of the treatment among the population globally is another major factor driving the growth of the segment.
Retail Pharmacies Dominated the Market Owing to the Rising Number of Pharmacies
The market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies based on distribution channel.
The retail pharmacies segment held the largest share in the global market in 2022. The dominance is due to the increasing number of retail pharmacies supplying joint pain injections globally.
On the other hand, the online pharmacies segment is anticipated to record a significant CAGR during the forecast period. The rising regulatory policies for online sales of prescription drugs in developed countries and the entry of leading e-pharmacy players in Germany, the U.K., and other countries are leading to a shift in patient preference toward online pharmacies.
Along with this, the lower selling prices of the injections by the online pharmacies is another major factor responsible for the growth of the segment.
The hospital pharmacies segment is anticipated to grow owing to factors such as the growing hospitalization rate of patients suffering from orthopedic conditions, rising patient visits to hospitals for the diagnosis of the condition, and others.
North America Joint Pain Injections Market Size, 2022 (USD Billion)
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North America to Hold Largest Market Share due to Well-established Reimbursement Policies
North America dominated the global market in 2022, with a valuation of USD 2.15 billion. The growing patient population suffering from joint pain, well-established reimbursement policies for intra-articular injections, and the increasing focus of market players on catering to the demand in countries such as the U.S. and Canada are the major factors responsible for driving the growth of the North America market.
Europe accounted for the second-largest market share since a large patient pool suffers from pain associated with musculoskeletal disorders such as arthritis. Further, the presence of skilled professionals and the introduction of novel intra-articular pain injections in Europe is expected to foster growth.
The rising focus of the players in the market to develop and launch novel therapies for knee osteoarthritis in the region is another major factor anticipated to spur the demand and adoption of the injections in the region.
On the other hand, the Asia Pacific joint pain injections market growth is expected to be highest during the forecast period. The growing prevalence of osteoarthritis and the introduction of viscosupplement products by players in the region are driving the market growth in Asian countries. Moreover, the rising awareness about innovative treatments for joint pain in the region also provides favorable conditions for adoption of these treatments among the patient population.
Latin America and the Middle East & Africa regions held a lower share in the global market. However, the increasing cases of arthritis and the rising adoption of technologically advanced solutions for pain management in these regions are expected to drive the market growth in the near future.
The rising focus of the market players to increase the accessibility and penetration of their products in these emerging countries is anticipated to drive the adoption of pain injections in these regions.
Strong Portfolio of Sanofi, Zimmer Biomet, Bioventus Inc., and Anika Therapeutics, Inc. to Boost Market Position
The global market is fragmented, with several players operating with a wide product portfolio globally.
The key players, such as Sanofi, Bioventus Inc., Anika Therapeutics, Inc., and others, dominated the market in 2022. The dominance of these players is attributed to their strong distribution network, strategic collaborations, and robust product portfolio of intra-articular injections. The key companies operating in the market are developing innovative products to gain a competitive advantage over other market players.
The rising focus of these companies on increasing the accessibility and adoption of their viscosupplementation products is anticipated to fuel their market share.
Similarly, the increasing number of strategic mergers and acquisitions among the market players is another factor propelling the market share of these players. These strategic partnerships and collaborations are expected to increase the accessibility and availability of the products globally, which is leading to a growing adoption of these products among the patient population.
Other players, such as Pfizer, Inc., Teva Pharmaceutical Industries Ltd., Novartis AG, and others, dominated the global market with their corticosteroid injection product portfolio.
An Infographic Representation of Joint Pain Injections Market
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The research report provides an overall scenario of the market. It focuses on key aspects such as leading companies, product, joint type, and distribution channels. Besides this, it offers insights into the trends in the global market, highlights key industry developments, and COVID-19 impact on the market. In addition to the factors mentioned above, the report encompasses several factors that have contributed to the market growth in recent years.
CAGR of 8.6% from 2023-2030
Value (USD billion)
By Product, Joint Type, Distribution Channel, and Region
By Joint Type
By Distribution Channel
Fortune Business Insights says that the global market stood at USD 4.79 billion in 2022 and is projected to reach USD 9.20 billion by 2030.
In 2022, the market size of North America was 2.15 billion.
The market will grow at a CAGR of 8.6% during the forecast period (2023-2030).
By product, the hyaluronic acid injections segment will lead the market.
Rising prevalence of osteoarthritis and obesity, presence of potential pipeline candidates for pain relief in osteoarthritis, and rising adoption of the injections among the population will propel the market growth.
Sanofi, Bioventus, Anika Therapeutics Inc., and SEIKAGAKU CORPORATION are the top players in the market.
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